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Medicine

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103
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Overview

Keertan Dheda is affiliated with the University of Cape Town in South Africa. Their research primarily focuses on infectious diseases, particularly tuberculosis and respiratory conditions, with a significant volume of publications in medicine and related subfields.

Their work heavily intersects with tuberculosis research and epidemiology, as well as SARS-CoV-2 and COVID-19 studies. The scientist has contributed extensively to the understanding of Mycobacterium research and diagnosis, COVID-19 clinical research studies, and pneumonia and respiratory infections, including Pneumocystis jirovecii pneumonia detection and treatment.

Frequent coauthors collaborating with Keertan Dheda include:

  • Aliasgar Esmail
  • Suzette Oelofse
  • Shabir A. Madhi
  • Qasim Bhorat
  • Lee Fairlie

Their research has appeared repeatedly in a range of publication venues, including:

  • African Journal of Thoracic and Critical Care Medicine
  • bioRxiv (Cold Spring Harbor Laboratory)
  • SSRN Electronic Journal
  • International Journal of Infectious Diseases
  • Open Forum Infectious Diseases

Significant recent papers authored or coauthored by Keertan Dheda include:

  • "Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK" (2020) published in The Lancet
  • "Efficacy of the ChAdOx1 nCoV-19 Covid-19 Vaccine against the B.1.351 Variant" (2021) published in New England Journal of Medicine
  • "Single-dose administration and the influence of the timing of the booster dose on immunogenicity and efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine: a pooled analysis of four randomised trials" (2021) published in The Lancet
  • "Efficacy of NVX-CoV2373 Covid-19 Vaccine against the B.1.351 Variant" (2021) published in New England Journal of Medicine
  • "The intersecting pandemics of tuberculosis and COVID-19: population-level and patient-level impact, clinical presentation, and corrective interventions" (2022) published in The Lancet Respiratory Medicine

The scientist's main fields of study include:

  • Medicine

Subfields of study where Keertan Dheda has contributed research include:

  • Infectious Diseases
  • Epidemiology
  • Pulmonary and Respiratory Medicine
  • Surgery
  • Radiology, Nuclear Medicine and Imaging

Major topics covered through the scientist's research encompass:

  • Tuberculosis Research and Epidemiology
  • SARS-CoV-2 and COVID-19 Research
  • Mycobacterium research and diagnosis
  • COVID-19 Clinical Research Studies
  • Infectious Diseases and Tuberculosis
  • Pneumonia and Respiratory Infections
  • Pneumocystis jirovecii pneumonia detection and treatment

Best Publications

  • Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK.

    M Voysey;Clemens Sac.;S A Madhi;L Y Weckx

  • Real-time RT-PCR normalisation; strategies and considerations

    J Huggett;K Dheda;K Dheda;S Bustin;A Zumla

  • Multidrug-resistant and extensively drug-resistant tuberculosis: a threat to global control of tuberculosis

    Neel R Gandhi;Paul Nunn;Keertan Dheda;Keertan Dheda;H Simon Schaaf

  • Validation of housekeeping genes for normalizing RNA expression in real-time PCR

    Keertan Dheda;Jim F. Huggett;Stephen A. Bustin;Margaret A. Johnson

  • Single-dose administration and the influence of the timing of the booster dose on immunogenicity and efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine: a pooled analysis of four randomised trials.

    M Voysey;S A Costa Clemens;S A Madhi;L Y Weckx

  • Efficacy of the ChAdOx1 nCoV-19 Covid-19 Vaccine against the B.1.351 Variant.

    S. A. Madhi;V. Baillie;C. L. Cutland;M. Voysey

  • Gamma Interferon Release Assays for Detection of Mycobacterium tuberculosis Infection

    Madhukar Pai;Claudia M. Denkinger;Claudia M. Denkinger;Sandra V. Kik;Molebogeng X. Rangaka

  • The implications of using an inappropriate reference gene for real-time reverse transcription PCR data normalization

    K. Dheda;J.F. Huggett;J.S. Chang;L.U. Kim

  • Interferon-γ release assays for the diagnosis of active tuberculosis: a systematic review and meta-analysis

    Martina Sester;Giovanni Sotgiu;Christoph Lange;Claudia Giehl

  • The epidemiology, pathogenesis, transmission, diagnosis, and management of multidrug-resistant, extensively drug-resistant, and incurable tuberculosis

    Keertan Dheda;Tawanda Gumbo;Gary Maartens;Kelly E. Dooley

  • Treatment correlates of successful outcomes in pulmonary multidrug-resistant tuberculosis: an individual patient data meta-analysis

    Nafees Ahmad;Shama D Ahuja;Onno W Akkerman

  • Efficacy of NVX-CoV2373 Covid-19 Vaccine against the B.1.351 Variant.

    Vivek Shinde;Sutika Bhikha;Zaheer Hoosain;Moherndran Archary

  • Incipient and Subclinical Tuberculosis: a Clinical Review of Early Stages and Progression of Infection.

    Paul K. Drain;Kristina L. Bajema;David Dowdy;Keertan Dheda

  • Feasibility, accuracy, and clinical effect of point-of-care Xpert MTB/RIF testing for tuberculosis in primary-care settings in Africa: a multicentre, randomised, controlled trial

    Grant Theron;Lynn Zijenah;Duncan Chanda;Petra Clowes;Petra Clowes

  • New tools and emerging technologies for the diagnosis of tuberculosis: part I. Latent tuberculosis.

    Madhukar Pai;Shriprakash Kalantri;Keertan Dheda

  • Functional capacity of Mycobacterium tuberculosis-specific T cell responses in humans is associated with mycobacterial load

    Cheryl L. Day;Cheryl L. Day;Deborah A. Abrahams;Lesedi Lerumo;Esme Janse van Rensburg

  • Evaluation of the Xpert MTB/RIF Assay for the Diagnosis of Pulmonary Tuberculosis in a High HIV Prevalence Setting

    Grant Theron;Jonny Peter;Richard van Zyl-Smit;Hridesh Mishra

  • Supervised and unsupervised self-testing for HIV in high- and low-risk populations: a systematic review.

    Nitika Pant Pai;Jigyasa Sharma;Sushmita Shivkumar;Sabrina Pillay

  • Global lung health: the colliding epidemics of tuberculosis, tobacco smoking, HIV and COPD

    R. N. van Zyl Smit;M. Pai;W. W. Yew;C. C. Leung

  • Single Dose Administration, And The Influence Of The Timing Of The Booster Dose On Immunogenicity and Efficacy Of ChAdOx1 nCoV-19 (AZD1222) Vaccine (preprint)

    Voysey, Merryn, Costa Clemens, Sue Ann, Madhi, Shabir A.;Weckx, Lily Yin, Folegatti, Pedro M.;Parvinder K. Aley;Angus, Brian John, Baillie, Vicky, Barnabas, Shaun L.

Frequent Co-Authors

Alimuddin Zumla
Alimuddin Zumla University College London
Madhukar Pai
Madhukar Pai McGill University
Graham A. W. Rook
Graham A. W. Rook University College London
Robin M. Warren
Robin M. Warren Stellenbosch University
Tawanda Gumbo
Tawanda Gumbo Baylor University Medical Center
Christoph Lange
Christoph Lange University of Lübeck
Jim F. Huggett
Jim F. Huggett University College London
Michael Hoelscher
Michael Hoelscher Ludwig-Maximilians-Universität München
Ruth McNerney
Ruth McNerney University of Cape Town
Eric D. Bateman
Eric D. Bateman University of Cape Town

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