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Sebastien Gagneux

Sebastien Gagneux

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Microbiology
Switzerland
2022

D-Index & Metrics

Microbiology

D-Index
88
Citations
30233
World Ranking
755
National Ranking
21

Medicine

D-Index
88
Citations
30880
World Ranking
13084
National Ranking
185

Research.com Recognitions

  • 2022 - Research.com Microbiology in Switzerland Leader Award

Overview

Sebastien Gagneux is affiliated with the University of Basel in Switzerland. Their research primarily focuses on the field of Medicine, with particular emphasis on Infectious Diseases, Epidemiology, Molecular Biology, Surgery, and Genetics.

The scientist's work encompasses several main topics, including:

  • Tuberculosis Research and Epidemiology
  • Mycobacterium research and diagnosis
  • Diagnosis and treatment of tuberculosis
  • Infectious Diseases and Tuberculosis
  • Evolution and Genetic Dynamics
  • Genomics and Phylogenetic Studies
  • Antibiotic Resistance in Bacteria

Frequent co-authors with whom they have collaborated include:

  • Sònia Borrell
  • Daniela Brites
  • Miriam Reinhard
  • Chloé Loiseau
  • Klaus Reither

Sebastien Gagneux has contributed to publications in multiple venues where they published more than once. The most frequent venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Antimicrobial Agents and Chemotherapy
  • Nature Communications
  • Microbial Genomics
  • The Lancet Microbe

Some of the recent papers authored or co-authored by Sebastien Gagneux are:

  • "A sister lineage of the Mycobacterium tuberculosis complex discovered in the African Great Lakes region" (2020, Nature Communications)
  • "Phylogenomics of Mycobacterium africanum reveals a new lineage and a complex evolutionary history" (2021, Microbial Genomics)
  • "Mycobacterium tuberculosis associated with severe tuberculosis evades cytosolic surveillance systems and modulates IL-1β production" (2020, Nature Communications)
  • "Evaluation of Nanopore sequencing for Mycobacterium tuberculosis drug susceptibility testing and outbreak investigation: a genomic analysis" (2022, The Lancet Microbe)
  • "Bedaquiline resistance in patients with drug-resistant tuberculosis in Cape Town, South Africa: a retrospective longitudinal cohort study" (2023, The Lancet Microbe)

Best Publications

  • Variable host-pathogen compatibility in Mycobacterium tuberculosis.

    Sebastien Gagneux;Kathryn DeRiemer;Tran Van;Midori Kato-Maeda

  • Out-of-Africa migration and Neolithic coexpansion of Mycobacterium tuberculosis with modern humans

    Iñaki Comas;Mireia Coscolla;Mireia Coscolla;Tao Luo;Sonia Borrell;Sonia Borrell

  • Global phylogeography of Mycobacterium tuberculosis and implications for tuberculosis product development

    Sebastien Gagneux;Peter M Small;Peter M Small

  • Human T cell epitopes of Mycobacterium tuberculosis are evolutionarily hyperconserved

    Iñaki Comas;Jaidip Chakravartti;Peter M Small;James Galagan

  • The competitive cost of antibiotic resistance in Mycobacterium tuberculosis.

    Sebastien Gagneux;Clara Davis Long;Peter M. Small;Peter M. Small;Tran Van

  • High functional diversity in Mycobacterium tuberculosis driven by genetic drift and human demography.

    Ruth Hershberg;Mikhail Lipatov;Peter M Small;Peter M Small;Hadar Sheffer

  • Whole-genome sequencing of rifampicin-resistant Mycobacterium tuberculosis strains identifies compensatory mutations in RNA polymerase genes.

    Iñaki Comas;Sonia Borrell;Sonia Borrell;Andreas Roetzer;Graham Rose

  • Pre-Columbian mycobacterial genomes reveal seals as a source of New World human tuberculosis

    Kirsten I. Bos;Kelly M. Harkins;Alexander Herbig;Mireia Coscolla

  • Ecology and evolution of Mycobacterium tuberculosis.

    Sebastien Gagneux;Sebastien Gagneux

  • The influence of host and bacterial genotype on the development of disseminated disease with Mycobacterium tuberculosis

    Maxine Caws;Maxine Caws;Guy Thwaites;Sarah Dunstan;Sarah Dunstan;Thomas R. Hawn

  • Evolutionary history and global spread of the Mycobacterium tuberculosis Beijing lineage

    Matthias Merker;Camille Blin;Stefano Mona;Nicolas Duforet-Frebourg

  • Genomic analysis identifies targets of convergent positive selection in drug-resistant Mycobacterium tuberculosis

    Maha R Farhat;B Jesse Shapiro;Karen J Kieser;Razvan Sultana

  • Host-pathogen coevolution in human tuberculosis.

    Sebastien Gagneux

  • Genotyping of genetically monomorphic bacteria: DNA sequencing in Mycobacterium tuberculosis highlights the limitations of current methodologies.

    Iñaki Comas;Susanne Homolka;Stefan Niemann;Sebastien Gagneux

  • Mycobacterium tuberculosis mutation rate estimates from different lineages predict substantial differences in the emergence of drug-resistant tuberculosis

    Christopher B Ford;Rupal R Shah;Midori Kato Maeda;Sebastien Gagneux;Sebastien Gagneux

  • Consequences of genomic diversity in Mycobacterium tuberculosis.

    Mireia Coscolla;Sebastien Gagneux;Sebastien Gagneux

  • Antimicrobial resistance in Mycobacterium tuberculosis: mechanistic and evolutionary perspectives

    Sebastian M. Gygli;Sebastian M. Gygli;Sonia Borrell;Sonia Borrell;Andrej Trauner;Andrej Trauner;Sebastien Gagneux;Sebastien Gagneux

  • Mycobacterium tuberculosis lineage 4 comprises globally distributed and geographically restricted sublineages.

    David Stucki;David Stucki;Daniela Brites;Daniela Brites;Leïla Jeljeli;Mireia Coscolla;Mireia Coscolla

  • Whole genome sequencing of Mycobacterium tuberculosis: current standards and open issues.

    Conor J. Meehan;Galo A. Goig;Thomas A. Kohl;Lennert Verboven

  • Mycobacterium africanum—Review of an Important Cause of Human Tuberculosis in West Africa

    Bouke C. de Jong;Martin Antonio;Sebastien Gagneux;Sebastien Gagneux

  • Progression to Active Tuberculosis, but Not Transmission, Varies by Mycobacterium tuberculosis Lineage in The Gambia

    Bouke C de Jong;Philip C Hill;Alex Aiken;Timothy Awine

Frequent Co-Authors

Sonia Borrell
Sonia Borrell Swiss Tropical and Public Health Institute
Stefan Niemann
Stefan Niemann Research Center Borstel - Leibniz-Center for Medicine and Biosciences
Robert J. Wilkinson
Robert J. Wilkinson The Francis Crick Institute
Matthias Egger
Matthias Egger University of Bern
Peter M. Small
Peter M. Small Bill & Melinda Gates Foundation
Julian Parkhill
Julian Parkhill University of Cambridge
Erik C. Böttger
Erik C. Böttger University of Zurich
Moses Joloba
Moses Joloba Makerere University
Simon R. Harris
Simon R. Harris Wellcome Sanger Institute

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