Sebastien Gagneux mainly investigates Mycobacterium tuberculosis, Tuberculosis, Genetics, Mycobacterium tuberculosis complex and Drug resistance. His research integrates issues of Lineage, Virology, Phylogenetics, Lineage and Immunology in his study of Mycobacterium tuberculosis. His Tuberculosis research is multidisciplinary, incorporating elements of Evolutionary biology, Antibiotic resistance and Disease.
In Genetics, Sebastien Gagneux works on issues like Population genetics, which are connected to Genetic diversity, Human genetics, Allopatric speciation, Sympatric speciation and Human pathogen. His Drug resistance research integrates issues from Ethionamide, Internal medicine, Antibiotics and Prothionamide. The study incorporates disciplines such as Epitope, Sequence analysis and DNA sequencing in addition to Genome.
His primary areas of study are Mycobacterium tuberculosis, Tuberculosis, Genetics, Mycobacterium tuberculosis complex and Virology. His Mycobacterium tuberculosis study integrates concerns from other disciplines, such as Lineage, Genome, Antibiotic resistance, Genotype and Drug resistance. His Drug resistance study incorporates themes from Antibiotics and Rifampicin.
The study incorporates disciplines such as Evolutionary biology, Internal medicine, Disease and Immunology in addition to Tuberculosis. His study looks at the relationship between Mycobacterium tuberculosis complex and fields such as Virulence, as well as how they intersect with chemical problems. His research in Virology intersects with topics in rpoB and Molecular epidemiology.
His scientific interests lie mostly in Mycobacterium tuberculosis, Tuberculosis, Mycobacterium tuberculosis complex, Genetics and Evolutionary biology. His Mycobacterium tuberculosis research integrates issues from Genetic variation, Minimum inhibitory concentration, Antibiotic resistance, Computational biology and Drug resistance. His Drug resistance research includes themes of Rifampicin and Virology.
His Tuberculosis research incorporates themes from Internal medicine, Disease and Immune system, Immunology. His Mycobacterium tuberculosis complex research is multidisciplinary, incorporating perspectives in Genome, Gene, Genetic diversity and Single-nucleotide polymorphism. The various areas that Sebastien Gagneux examines in his Evolutionary biology study include Phylogeography, Lineage, Population genetics and Coalescent theory.
His primary scientific interests are in Mycobacterium tuberculosis, Mycobacterium tuberculosis complex, Tuberculosis, Evolutionary biology and Lineage. Sebastien Gagneux combines subjects such as SNP, Single-nucleotide polymorphism, Genetics and Genetic variation with his study of Mycobacterium tuberculosis. His Mycobacterium tuberculosis complex research focuses on Genetic diversity and how it connects with Genomics, Computational biology and Genetic association.
His Tuberculosis research is multidisciplinary, relying on both Inflammasome, Immunology, Immune system, Cytokine and Secretion. While the research belongs to areas of Evolutionary biology, he spends his time largely on the problem of Phylogeography, intersecting his research to questions surrounding Mycobacterium africanum, Phylogenomics, Mycobacterium caprae, Mycobacterium bovis and Molecular clock. The Lineage study combines topics in areas such as Adaptation, Genome and Clade.
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Variable host-pathogen compatibility in Mycobacterium tuberculosis.
Sebastien Gagneux;Kathryn DeRiemer;Tran Van;Midori Kato-Maeda.
Proceedings of the National Academy of Sciences of the United States of America (2006)
Out-of-Africa migration and Neolithic coexpansion of Mycobacterium tuberculosis with modern humans
Iñaki Comas;Mireia Coscolla;Mireia Coscolla;Tao Luo;Sonia Borrell;Sonia Borrell.
Nature Genetics (2013)
Global phylogeography of Mycobacterium tuberculosis and implications for tuberculosis product development
Sebastien Gagneux;Peter M Small;Peter M Small.
Lancet Infectious Diseases (2007)
Human T cell epitopes of Mycobacterium tuberculosis are evolutionarily hyperconserved
Iñaki Comas;Jaidip Chakravartti;Peter M Small;James Galagan.
Nature Genetics (2010)
The competitive cost of antibiotic resistance in Mycobacterium tuberculosis.
Sebastien Gagneux;Clara Davis Long;Peter M. Small;Peter M. Small;Tran Van.
High functional diversity in Mycobacterium tuberculosis driven by genetic drift and human demography.
Ruth Hershberg;Mikhail Lipatov;Peter M Small;Peter M Small;Hadar Sheffer.
PLOS Biology (2008)
The influence of host and bacterial genotype on the development of disseminated disease with Mycobacterium tuberculosis
Maxine Caws;Maxine Caws;Guy Thwaites;Sarah Dunstan;Sarah Dunstan;Thomas R. Hawn.
PLOS Pathogens (2008)
Whole-genome sequencing of rifampicin-resistant Mycobacterium tuberculosis strains identifies compensatory mutations in RNA polymerase genes.
Iñaki Comas;Sonia Borrell;Sonia Borrell;Andreas Roetzer;Graham Rose.
Nature Genetics (2012)
Genotyping of genetically monomorphic bacteria: DNA sequencing in Mycobacterium tuberculosis highlights the limitations of current methodologies.
Iñaki Comas;Susanne Homolka;Stefan Niemann;Sebastien Gagneux.
PLOS ONE (2009)
Pre-Columbian mycobacterial genomes reveal seals as a source of New World human tuberculosis
Kirsten I. Bos;Kelly M. Harkins;Alexander Herbig;Mireia Coscolla.
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