2023 - Research.com Microbiology in France Leader Award
Roland Brosch spends much of his time researching Mycobacterium tuberculosis, Microbiology, Genetics, Mycobacterium bovis and Virulence. The study incorporates disciplines such as Phagosome, Secretion and History of tuberculosis in addition to Mycobacterium tuberculosis. His Microbiology study combines topics in areas such as Mycobacterium marinum, Mycobacterium, Bacteria and Effector.
His Mycobacterium bovis research incorporates elements of Mycobacterium tuberculosis complex and Virology. His Virology study combines topics from a wide range of disciplines, such as Tuberculosis vaccines, ESAT-6 and Immunogenicity. His Antigen research extends to the thematically linked field of Virulence.
Mycobacterium tuberculosis, Microbiology, Virulence, Genetics and Virology are his primary areas of study. His work carried out in the field of Mycobacterium tuberculosis brings together such families of science as Secretion, Genome and Mycobacterium. His Mycobacterium research includes themes of Human pathogen and Mycobacterium smegmatis.
His Microbiology research focuses on Immune system and how it connects with Effector. His Virulence research includes elements of Plasmid, Pathogen, Mutant and Bacteria. His Virology research incorporates themes from Tuberculosis vaccines and Immunogenicity.
Roland Brosch mainly investigates Mycobacterium tuberculosis, Virulence, Microbiology, Immune system and Mycobacterium. His Mycobacterium tuberculosis study integrates concerns from other disciplines, such as Genome, Genetics, BCG vaccine and Secretion. The Genome study combines topics in areas such as Mycobacterium africanum, Immunogenicity and Mycobacterium smegmatis.
The various areas that he examines in his Virulence study include Mutation, Lineage, Pathogen and Phylogenetic tree. His Microbiology study integrates concerns from other disciplines, such as Mycobacterium Infections, Bedaquiline, Innate immune system and Mycobacterium bovis. His study focuses on the intersection of Mycobacterium tuberculosis complex and fields such as Virology with connections in the field of ESAT-6, CFP-10 and Lineage.
His primary areas of study are Mycobacterium tuberculosis, Virulence, Microbiology, Secretion and Genetics. His research in Mycobacterium tuberculosis intersects with topics in T cell, MHC class II, T-cell receptor, Cell biology and Epitope. His biological study spans a wide range of topics, including Bedaquiline and Immunity.
He focuses mostly in the field of Secretion, narrowing it down to matters related to Immune system and, in some cases, Antigen, BCG vaccine and Host–pathogen interaction. The study incorporates disciplines such as Mycobacterium tuberculosis complex and Mycobacterium africanum in addition to Genetics. His studies in Mycobacterium tuberculosis complex integrate themes in fields like Mycobacterium, Genome, Genomics, Immunogenicity and Phenotypic trait.
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Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence
S. T. Cole;R. Brosch;J. Parkhill;T. Garnier.
Nature (1998)
A new evolutionary scenario for the Mycobacterium tuberculosis complex
R. Brosch;S. V. Gordon;M. Marmiesse;P. Brodin.
Proceedings of the National Academy of Sciences of the United States of America (2002)
Loss of RD1 contributed to the attenuation of the live tuberculosis vaccines Mycobacterium bovis BCG and Mycobacterium microti.
Alexander S. Pym;Priscille Brodin;Roland Brosch;Michel Huerre.
Molecular Microbiology (2002)
Ancient origin and gene mosaicism of the progenitor of Mycobacterium tuberculosis.
M. Cristina Gutierrez;Sylvain Brisse;Roland Brosch;Michel Fabre.
PLOS Pathogens (2005)
Recombinant BCG exporting ESAT-6 confers enhanced protection against tuberculosis.
Alexander S. Pym;Alexander S. Pym;Priscille Brodin;Laleh Majlessi;Roland Brosch.
Nature Medicine (2003)
Benzothiazinones Kill Mycobacterium tuberculosis by Blocking Arabinan Synthesis
Vadim Makarov;Giulia Manina;Katarina Mikusova;Ute Möllmann.
Science (2009)
Identification of variable regions in the genomes of tubercle bacilli using bacterial artificial chromosome arrays.
Stephen V. Gordon;Roland Brosch;Alain Billault;Thierry Garnier.
Molecular Microbiology (1999)
Genome plasticity of BCG and impact on vaccine efficacy.
Roland Brosch;Stephen V. Gordon;Thierry Garnier;Karin Eiglmeier.
Proceedings of the National Academy of Sciences of the United States of America (2007)
Insights from the complete genome sequence of Mycobacterium marinum on the evolution of Mycobacterium tuberculosis
Timothy P. Stinear;Torsten Seemann;Paul F. Harrison;Grant A. Jenkin.
Genome Research (2008)
Phagosomal rupture by Mycobacterium tuberculosis results in toxicity and host cell death.
Roxane Simeone;Alexandre Bobard;Juliane Lippmann;Wilbert Bitter.
PLOS Pathogens (2012)
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