D-Index & Metrics Best Publications
Microbiology
France
2023

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Microbiology D-index 81 Citations 34,570 197 World Ranking 642 National Ranking 32

Research.com Recognitions

Awards & Achievements

2023 - Research.com Microbiology in France Leader Award

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Bacteria
  • Enzyme

Roland Brosch spends much of his time researching Mycobacterium tuberculosis, Microbiology, Genetics, Mycobacterium bovis and Virulence. The study incorporates disciplines such as Phagosome, Secretion and History of tuberculosis in addition to Mycobacterium tuberculosis. His Microbiology study combines topics in areas such as Mycobacterium marinum, Mycobacterium, Bacteria and Effector.

His Mycobacterium bovis research incorporates elements of Mycobacterium tuberculosis complex and Virology. His Virology study combines topics from a wide range of disciplines, such as Tuberculosis vaccines, ESAT-6 and Immunogenicity. His Antigen research extends to the thematically linked field of Virulence.

His most cited work include:

  • Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence (6751 citations)
  • A new evolutionary scenario for the Mycobacterium tuberculosis complex (1270 citations)
  • Loss of RD1 contributed to the attenuation of the live tuberculosis vaccines Mycobacterium bovis BCG and Mycobacterium microti. (584 citations)

What are the main themes of his work throughout his whole career to date?

Mycobacterium tuberculosis, Microbiology, Virulence, Genetics and Virology are his primary areas of study. His work carried out in the field of Mycobacterium tuberculosis brings together such families of science as Secretion, Genome and Mycobacterium. His Mycobacterium research includes themes of Human pathogen and Mycobacterium smegmatis.

His Microbiology research focuses on Immune system and how it connects with Effector. His Virulence research includes elements of Plasmid, Pathogen, Mutant and Bacteria. His Virology research incorporates themes from Tuberculosis vaccines and Immunogenicity.

He most often published in these fields:

  • Mycobacterium tuberculosis (52.47%)
  • Microbiology (52.02%)
  • Virulence (29.60%)

What were the highlights of his more recent work (between 2017-2021)?

  • Mycobacterium tuberculosis (52.47%)
  • Virulence (29.60%)
  • Microbiology (52.02%)

In recent papers he was focusing on the following fields of study:

Roland Brosch mainly investigates Mycobacterium tuberculosis, Virulence, Microbiology, Immune system and Mycobacterium. His Mycobacterium tuberculosis study integrates concerns from other disciplines, such as Genome, Genetics, BCG vaccine and Secretion. The Genome study combines topics in areas such as Mycobacterium africanum, Immunogenicity and Mycobacterium smegmatis.

The various areas that he examines in his Virulence study include Mutation, Lineage, Pathogen and Phylogenetic tree. His Microbiology study integrates concerns from other disciplines, such as Mycobacterium Infections, Bedaquiline, Innate immune system and Mycobacterium bovis. His study focuses on the intersection of Mycobacterium tuberculosis complex and fields such as Virology with connections in the field of ESAT-6, CFP-10 and Lineage.

Between 2017 and 2021, his most popular works were:

  • Mutations in ppe38 block PE_PGRS secretion and increase virulence of Mycobacterium tuberculosis. (63 citations)
  • Identification of genes required for Mycobacterium abscessus growth in vivo with a prominent role of the ESX-4 locus (41 citations)
  • Evolution of virulence in the Mycobacterium tuberculosis complex (38 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Bacteria
  • DNA

His primary areas of study are Mycobacterium tuberculosis, Virulence, Microbiology, Secretion and Genetics. His research in Mycobacterium tuberculosis intersects with topics in T cell, MHC class II, T-cell receptor, Cell biology and Epitope. His biological study spans a wide range of topics, including Bedaquiline and Immunity.

He focuses mostly in the field of Secretion, narrowing it down to matters related to Immune system and, in some cases, Antigen, BCG vaccine and Host–pathogen interaction. The study incorporates disciplines such as Mycobacterium tuberculosis complex and Mycobacterium africanum in addition to Genetics. His studies in Mycobacterium tuberculosis complex integrate themes in fields like Mycobacterium, Genome, Genomics, Immunogenicity and Phenotypic trait.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence

S. T. Cole;R. Brosch;J. Parkhill;T. Garnier.
Nature (1998)

9667 Citations

A new evolutionary scenario for the Mycobacterium tuberculosis complex

R. Brosch;S. V. Gordon;M. Marmiesse;P. Brodin.
Proceedings of the National Academy of Sciences of the United States of America (2002)

2153 Citations

Loss of RD1 contributed to the attenuation of the live tuberculosis vaccines Mycobacterium bovis BCG and Mycobacterium microti.

Alexander S. Pym;Priscille Brodin;Roland Brosch;Michel Huerre.
Molecular Microbiology (2002)

893 Citations

Ancient origin and gene mosaicism of the progenitor of Mycobacterium tuberculosis.

M. Cristina Gutierrez;Sylvain Brisse;Roland Brosch;Michel Fabre.
PLOS Pathogens (2005)

827 Citations

Recombinant BCG exporting ESAT-6 confers enhanced protection against tuberculosis.

Alexander S. Pym;Alexander S. Pym;Priscille Brodin;Laleh Majlessi;Roland Brosch.
Nature Medicine (2003)

801 Citations

Benzothiazinones Kill Mycobacterium tuberculosis by Blocking Arabinan Synthesis

Vadim Makarov;Giulia Manina;Katarina Mikusova;Ute Möllmann.
Science (2009)

732 Citations

Identification of variable regions in the genomes of tubercle bacilli using bacterial artificial chromosome arrays.

Stephen V. Gordon;Roland Brosch;Alain Billault;Thierry Garnier.
Molecular Microbiology (1999)

719 Citations

Genome plasticity of BCG and impact on vaccine efficacy.

Roland Brosch;Stephen V. Gordon;Thierry Garnier;Karin Eiglmeier.
Proceedings of the National Academy of Sciences of the United States of America (2007)

644 Citations

Insights from the complete genome sequence of Mycobacterium marinum on the evolution of Mycobacterium tuberculosis

Timothy P. Stinear;Torsten Seemann;Paul F. Harrison;Grant A. Jenkin.
Genome Research (2008)

576 Citations

Phagosomal rupture by Mycobacterium tuberculosis results in toxicity and host cell death.

Roxane Simeone;Alexandre Bobard;Juliane Lippmann;Wilbert Bitter.
PLOS Pathogens (2012)

526 Citations

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