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Claude Leclerc

Claude Leclerc

D-Index & Metrics

Immunology

D-Index
84
Citations
21603
World Ranking
1404
National Ranking
54

Medicine

D-Index
84
Citations
21600
World Ranking
15278
National Ranking
493

Overview

Claude Leclerc is affiliated with Inserm in France, focusing primarily on research within Medicine, Immunology and Microbiology, and Biochemistry, Genetics and Molecular Biology. Their work spans several subfields, including Immunology, Molecular Biology, Infectious Diseases, Epidemiology, and Radiology, Nuclear Medicine and Imaging.

The scientist's research concentrates on key topics such as Immunotherapy and Immune Responses, Monoclonal and Polyclonal Antibodies Research, vaccines and immunoinformatics approaches, Tuberculosis Research and Epidemiology, Mycobacterium research and diagnosis, Cytomegalovirus and herpesvirus research, and Cancer Immunotherapy and Biomarkers.

Claude Leclerc has published scholarly work in various scientific journals. Notable recent papers include:

  • The fully synthetic glycopeptide MAG-Tn3 therapeutic vaccine induces tumor-specific cytotoxic antibodies in breast cancer patients, 2020, Cancer Immunology Immunotherapy
  • Immune Profiling Enables Stratification of Patients With Active Tuberculosis Disease or Mycobacteriu m tuberculosis Infection, 2020, Clinical Infectious Diseases
  • IL-17 suppresses the therapeutic activity of cancer vaccines through the inhibition of CD8 + T-cell responses, 2020, OncoImmunology
  • TLR9 activation is required for cytotoxic response elicited by baculovirus capsid display, 2022, Immunology
  • The EFIS vaccination task force expert report, 2021, European Journal of Immunology

Frequent publication venues where Claude Leclerc's work appears include:

  • Cancer Immunology Immunotherapy
  • Clinical Infectious Diseases
  • OncoImmunology
  • Immunology
  • European Journal of Immunology

Collaborations have been made with other researchers, with repeated coauthorships observed with:

  • Pierre Rosenbaum
  • Darragh Duffy
  • Matthew L. Albert
  • Cécile Artaud
  • Sylvie Bay

Best Publications

  • Neonatal adaptive immunity comes of age

    Becky Adkins;Claude Leclerc;Stuart Marshall-Clarke

  • Recombinant BCG exporting ESAT-6 confers enhanced protection against tuberculosis.

    Alexander S. Pym;Alexander S. Pym;Priscille Brodin;Laleh Majlessi;Roland Brosch

  • The Adenylate Cyclase Toxin of Bordetella pertussis Binds to Target Cells via the αMβ2 Integrin (Cd11b/Cd18)

    Pierre Guermonprez;Nadia Khelef;Eric Blouin;Philippe Rieu

  • Carrier-induced epitopic suppression, a major issue for future synthetic vaccines.

    M P Schutze;C Leclerc;M Jolivet;F Audibert

  • Dissection of ESAT-6 System 1 of Mycobacterium tuberculosis and Impact on Immunogenicity and Virulence

    Priscille Brodin;Laleh Majlessi;Laurent Marsollier;Marien I. de Jonge

  • Coactivation of Syk Kinase and MyD88 Adaptor Protein Pathways by Bacteria Promotes Regulatory Properties of Neutrophils

    Xiaoming Zhang;Laleh Majlessi;Laleh Majlessi;Edith Deriaud;Edith Deriaud;Claude Leclerc;Claude Leclerc

  • Reduced response to multiple vaccines sharing common protein epitopes that are administered simultaneously to infants

    Ron Dagan;Juhani Eskola;Claude Leclerc;Odile Leroy

  • Genomic analysis of smooth tubercle bacilli provides insights into ancestry and pathoadaptation of Mycobacterium tuberculosis

    Philip Supply;Michael Marceau;Sophie Mangenot;David Roche;David Roche

  • Control of M. tuberculosis ESAT-6 secretion and specific T cell recognition by PhoP.

    Wafa Frigui;Daria Bottai;Daria Bottai;Laleh Majlessi;Marc Monot

  • Dendritic Cells Are Host Cells for Mycobacteria In Vivo That Trigger Innate and Acquired Immunity

    Xinan Jiao;Richard Lo-Man;Pierre Guermonprez;Laurence Fiette

  • Recombinant parvovirus-like particles as an antigen carrier: A novel nonreplicative exogenous antigen to elicit protective antiviral cytotoxic T cells

    C. Sedlik;M.-F. Saron;J. Sarraseca;I. Casal

  • Upon TLR9 Signaling, CD5+ B Cells Control the IL-12-Dependent Th1-Priming Capacity of Neonatal DCs

    Cheng-Ming Sun;Edith Deriaud;Claude Leclerc;Richard Lo-Man

  • Functional analysis via standardized whole-blood stimulation systems defines the boundaries of a healthy immune response to complex stimuli.

    Darragh Duffy;Darragh Duffy;Vincent Rouilly;Valentina Libri;Milena Hasan

  • Molecular detection and in vivo analysis of the specific T cell response to a protein antigen.

    Madeleine Cochet;Christophe Pannetier;Armelle Regnault;Sylvie Darche

  • Disruption of the ESX-5 system of Mycobacterium tuberculosis causes loss of PPE protein secretion, reduction of cell wall integrity and strong attenuation.

    Daria Bottai;Mariagrazia Di Luca;Laleh Majlessi;Laleh Majlessi;Wafa Frigui

  • Functional Analysis of Early Secreted Antigenic Target-6, the Dominant T-cell Antigen of Mycobacterium tuberculosis, Reveals Key Residues Involved in Secretion, Complex Formation, Virulence, and Immunogenicity

    Priscille Brodin;Marien I. de Jonge;Laleh Majlessi;Claude Leclerc

  • Comparison of immune responses of mice immunized with five different Mycobacterium bovis BCG vaccine strains

    M. R. R. Lagranderie;A.-M. Balazuc;E. Deriaud;C. D. Leclerc

  • Plasmacytoid dendritic cells efficiently cross-prime naive T cells in vivo after TLR activation

    Juliette Mouriès;Juliette Mouriès;Gabriel Moron;Gabriel Moron;Géraldine Schlecht;Géraldine Schlecht;Nicolas Escriou

  • In vivo induction of cytotoxic T cell response by a free synthetic peptide requires CD4+ T cell help.

    C Fayolle;E Deriaud;C Leclerc

  • Type I interferons protect neonates from acute inflammation through interleukin 10–producing B cells

    Xiaoming Zhang;Xiaoming Zhang;Edith Deriaud;Xinan Jiao;Deborah Braun

  • A Fully Synthetic Therapeutic Vaccine Candidate Targeting Carcinoma-Associated Tn Carbohydrate Antigen Induces Tumor-Specific Antibodies in Nonhuman Primates

    Richard Lo-Man;Sophie Vichier-Guerre;Ronald Perraut;Edith Dériaud

Frequent Co-Authors

Maurice Hofnung
Maurice Hofnung Institut Pasteur
Peter Sebo
Peter Sebo Czech Academy of Sciences
Daniel Ladant
Daniel Ladant Institut Pasteur
Louis Chedid
Louis Chedid University of South Florida
Roland Brosch
Roland Brosch Institut Pasteur
Stewart T. Cole
Stewart T. Cole Institut Pasteur
Priscille Brodin
Priscille Brodin University of Lille
Agnes Ullmann
Agnes Ullmann Institut Pasteur
Sandra Hervas-Stubbs
Sandra Hervas-Stubbs University of Navarra
Alain Charbit
Alain Charbit Université Paris Cité

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