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Brigitte Gicquel

Brigitte Gicquel

D-Index & Metrics

Microbiology

D-Index
98
Citations
35957
World Ranking
455
National Ranking
25

Medicine

D-Index
95
Citations
31393
World Ranking
10111
National Ranking
310

Research.com Recognitions

  • 2018 - Member of Academia Europaea

Overview

Brigitte Gicquel is affiliated with the Institut Pasteur in France and has a research focus primarily in the fields of medicine and biochemistry, genetics, and molecular biology. Their work spans multiple subfields including infectious diseases, molecular biology, epidemiology, immunology, and oncology.

The main topics of their research include:

  • Tuberculosis research and epidemiology
  • Cancer therapeutics and mechanisms
  • Mycobacterium research and diagnosis
  • Diagnosis and treatment of tuberculosis
  • Pharmacological effects of natural compounds
  • Antibiotic resistance in bacteria
  • Cytokine signaling pathways and interactions

Recent publications authored or co-authored by Gicquel cover various aspects of infectious diseases and drug activity, with emphasis on tuberculosis and bacterial infection mechanisms. Notable recent papers include:

  • The antibiotic bedaquiline activates host macrophage innate immune resistance to bacterial infection, 2020, eLife
  • The zebrafish embryo as an in vivo model for screening nanoparticle-formulated lipophilic anti-tuberculosis compounds, 2021, Disease Models & Mechanisms
  • Phenanthrolinic analogs of quinolones show antibacterial activity against M. tuberculosis, 2020, European Journal of Medicinal Chemistry
  • A Hydrazine-Hydrazone Adamantine Compound Shows Antimycobacterial Activity and Is a Probable Inhibitor of MmpL3, 2022, Molecules
  • SigH stress response mediates killing of Mycobacterium tuberculosis by activating nitronaphthofuran prodrugs via induction of Mrx2 expression, 2022, Nucleic Acids Research

Frequent co-authors collaborating with Gicquel include:

  • Noelia Alonso-Rodríguez
  • Amel Kevin Alame Emane
  • Martin Speth
  • Claire Beauvineau
  • Gareth Griffiths

Gicquel's publications have appeared in journals that include:

  • eLife
  • Disease Models & Mechanisms
  • Molecules
  • Nucleic Acids Research
  • European Journal of Medicinal Chemistry

Recognition of their contributions includes becoming a Member of Academia Europaea in 2018.

Best Publications

  • Strain identification of Mycobacterium tuberculosis by DNA fingerprinting: recommendations for a standardized methodology.

    J D van Embden;M D Cave;J T Crawford;J W Dale

  • Mycobacterium abscessus: a new antibiotic nightmare

    Rachid Nessar;Emmanuelle Cambau;Jean Marc Reyrat;Alan Murray;Alan Murray

  • DC-SIGN Is the Major Mycobacterium tuberculosis Receptor on Human Dendritic Cells

    Ludovic Tailleux;Olivier Schwartz;Jean-Louis Herrmann;Elisabeth Pivert

  • Variable human minisatellite-like regions in the Mycobacterium tuberculosis genome.

    Philip Supply;Edith Mazars;Sarah Lesjean;Véronique Vincent

  • Identification of a virulence gene cluster of Mycobacterium tuberculosis by signature‐tagged transposon mutagenesis

    Luis Reinaldo Camacho;Danielle Ensergueix;Esther Perez;Brigitte Gicquel

  • A Mycobacterium tuberculosis operon encoding ESAT-6 and a novel low-molecular-mass culture filtrate protein (CFP-10).

    Fransois-Xavier Berthet;Peter Birk Rasmussen;Ida Rosenkrands;Peter Andersen

  • High-resolution minisatellite-based typing as a portable approach to global analysis of Mycobacterium tuberculosis molecular epidemiology

    Edith Mazars;Sarah Lesjean;Anne-Laure Banuls;Michèle Gilbert

  • IS6110, an IS-like element of Mycobacterium tuberculosis complex.

    Dominique Thierry;M. D. Cave;K. D. Eisenach;J. T. Crawford

  • Rapid diagnosis of tuberculosis by amplification of mycobacterial DNA in clinical samples.

    Anne Brisson-Noël;Denise Lecossier;Xavier Nassif;Brigitte Gicquel

  • Efficient allelic exchange and transposon mutagenesis in Mycobacterium tuberculosis

    Vladimir Pelicic;Mary Jackson;Jean Marc Reyrat;William R. Jacobs

  • An essential role for phoP in Mycobacterium tuberculosis virulence.

    Esther Pérez;Sofía Samper;Yann Bordas;Christophe Guilhot

  • Characterization of a Mycobacterium tuberculosis insertion sequence, IS6110, and its application in diagnosis

    Unknown

  • Analysis of the Phthiocerol Dimycocerosate Locus ofMycobacterium tuberculosis EVIDENCE THAT THIS LIPID IS INVOLVED IN THE CELL WALL PERMEABILITY BARRIER

    Luis R. Camacho;Patricia Constant;Catherine Raynaud;Marie Antoinette Lanéelle

  • Detection and identification of mycobacteria by amplification of mycobacterial DNA

    A. J. Hance;B. Grandchamp;V. Lévy-Frébault;D. Lecossier

  • Evolutionary Dynamics of Human Toll-Like Receptors and Their Different Contributions to Host Defense

    Luis B. Barreiro;Luis B. Barreiro;Meriem Ben-Ali;Hélène Quach;Guillaume Laval

  • Neutrophils rapidly migrate via lymphatics after Mycobacterium bovis BCG intradermal vaccination and shuttle live bacilli to the draining lymph nodes

    Valérie Abadie;Valérie Abadie;Valérie Abadie;Edgar Badell;Edgar Badell;Edgar Badell;Patrice Douillard;Patrice Douillard;Patrice Douillard;Danielle Ensergueix;Danielle Ensergueix;Danielle Ensergueix

  • Diagnosis of tuberculosis by DNA amplification in clinical practice evaluation

    A Brisson-Noel;C Aznar;C Chureau;S Nguyen

  • Is Adipose Tissue a Place for Mycobacterium tuberculosis Persistence

    Olivier Neyrolles;Olivier Neyrolles;Rogelio Hernández-Pando;Paul Fornès

  • Mycobacterial P1-Type ATPases Mediate Resistance to Zinc Poisoning in Human Macrophages

    Hélène Botella;Hélène Botella;Pascale Peyron;Pascale Peyron;Florence Levillain;Florence Levillain;Renaud Poincloux;Renaud Poincloux

  • Explosion of tuberculin-specific Th1-responses induces immune restoration syndrome in tuberculosis and HIV co-infected patients.

    Anne Bourgarit;Guislaine Carcelain;Valerie Martinez;Caroline Lascoux

  • Mutations in putative mutator genes of Mycobacterium tuberculosis strains of the W-Beijing family.

    Mina Ebrahimi Rad;Pablo Bifani;Carlos Martin;Kristin Kremer

  • Counterselectable Markers: Untapped Tools for Bacterial Genetics and Pathogenesis

    Jean-Marc Reyrat;Vladimir Pelicic;Vladimir Pelicic;Brigitte Gicquel;Rino Rappuoli

Frequent Co-Authors

Olivier Neyrolles
Olivier Neyrolles Paul Sabatier University
Mary Jackson
Mary Jackson Colorado State University
Carlos Martín
Carlos Martín Instituto de Salud Carlos III
Christophe Guilhot
Christophe Guilhot Paul Sabatier University
Luis B. Barreiro
Luis B. Barreiro University of Chicago
Germain Puzo
Germain Puzo Federal University of Toulouse Midi-Pyrénées
Lluis Quintana-Murci
Lluis Quintana-Murci Institut Pasteur
Martine Gilleron
Martine Gilleron Federal University of Toulouse Midi-Pyrénées
Agnes Ullmann
Agnes Ullmann Institut Pasteur
Priscille Brodin
Priscille Brodin University of Lille

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