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Biology and Biochemistry

D-Index
67
Citations
29221
World Ranking
8047
National Ranking
40

Overview

Stephen V. Gordon is affiliated with University College Dublin in Ireland. Their research primarily focuses on the field of Medicine, with extensive work in Biochemistry, Genetics, and Molecular Biology. Their subfields of study encompass Infectious Diseases, Epidemiology, Molecular Biology, Immunology, and Surgery.

The scientist's research addresses several main topics, including:

  • Mycobacterium research and diagnosis
  • Tuberculosis research and epidemiology
  • Microbial infections and disease research
  • RNA modifications and cancer
  • Cancer-related molecular mechanisms research
  • Genomics and phylogenetic studies
  • Immune cells in cancer

Recent publications illustrate a focus on mechanisms of host-pathogen interactions and microbial genomics. Notable papers include:

  • Mycobacterium tuberculosis Limits Host Glycolysis and IL-1β by Restriction of PFK-M via MicroRNA-21 (2020, Cell Reports)
  • Macrophage innate training induced by IL-4 and IL-13 activation enhances OXPHOS driven anti-mycobacterial responses (2022, eLife)
  • Lactate Alters Metabolism in Human Macrophages and Improves Their Ability to Kill Mycobacterium tuberculosis (2021, Frontiers in Immunology)
  • Mycobacterium bovis genomics reveals transmission of infection between cattle and deer in Ireland (2020, Microbial Genomics)
  • Phylodynamic analysis of an emergent Mycobacterium bovis outbreak in an area with no previously known wildlife infections (2021, Journal of Applied Ecology)

Stephen V. Gordon collaborates frequently with several researchers, particularly in the areas mentioned above. Frequent co-authors include:

  • Damien Farrell
  • John A. Browne
  • David E. MacHugh
  • Eamonn Gormley
  • Yasuhiko Suzuki

The scientist's output is often published in a consistent set of venues related to infectious diseases and microbiology. These venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Tuberculosis
  • Access Microbiology
  • Food Risk Assess Europe
  • Microbial Genomics

Best Publications

  • Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence

    S. T. Cole;R. Brosch;J. Parkhill;T. Garnier

  • A new evolutionary scenario for the Mycobacterium tuberculosis complex

    R. Brosch;S. V. Gordon;M. Marmiesse;P. Brodin

  • The complete genome sequence of Mycobacterium bovis

    Thierry Garnier;Karin Eiglmeier;Jean-Christophe Camus;Nadine Medina

  • Identification of variable regions in the genomes of tubercle bacilli using bacterial artificial chromosome arrays.

    Stephen V. Gordon;Roland Brosch;Alain Billault;Thierry Garnier

  • Genome plasticity of BCG and impact on vaccine efficacy.

    Roland Brosch;Stephen V. Gordon;Thierry Garnier;Karin Eiglmeier

  • Conclusive evidence that the major T-cell antigens of the Mycobacterium tuberculosis complex ESAT-6 and CFP-10 form a tight, 1:1 complex and characterization of the structural properties of ESAT-6, CFP-10, and the ESAT-6*CFP-10 complex. Implications for pathogenesis and virulence.

    Philip S. Renshaw;Parthena Panagiotidou;Adam Whelan;Stephen V. Gordon

  • Bottlenecks and broomsticks: the molecular evolution of Mycobacterium bovis

    Noel H. Smith;Noel H. Smith;Stephen V. Gordon;Ricardo de la Rua-Domenech;Richard S. Clifton-Hadley

  • Structure and Function of the Complex Formed by the Tuberculosis Virulence Factors Cfp-10 and Esat-6

    Philip S. Renshaw;Kirsty L. Lightbody;Vaclav Veverka;Frederick W. Muskett

  • Analysis of the proteome of Mycobacterium tuberculosis in silico.

    F. Tekaia;S.V. Gordon;T. Garnier;R. Brosch

  • Purification and properties of sialoadhesin, a sialic acid-binding receptor of murine tissue macrophages

    P.R. Crocker;S. Kelm;C. Dubois;B. Martin

  • Use of a Mycobacterium tuberculosis H37Rv Bacterial Artificial Chromosome Library for Genome Mapping, Sequencing, and Comparative Genomics

    Roland Brosch;Stephen V. Gordon;Alain Billault;Thierry Garnier

  • Isolation and characterization of resident stromal macrophages and hematopoietic cell clusters from mouse bone marrow.

    P R Crocker;S Gordon

  • The evolution of mycobacterial pathogenicity: clues from comparative genomics.

    Roland Brosch;Alexander S. Pym;Stephen V. Gordon;Stewart T. Cole

  • Myths and misconceptions: the origin and evolution of Mycobacterium tuberculosis

    Noel H. Smith;R. Glyn Hewinson;Kristin Kremer;Roland Brosch

  • Mycobacterial Lineages Causing Pulmonary and Extrapulmonary Tuberculosis, Ethiopia

    Rebuma Firdessa;Stefan Berg;Elena Hailu;Esther Schelling

  • Properties and distribution of a lectin-like hemagglutinin differentially expressed by murine stromal tissue macrophages.

    P R Crocker;S Gordon

  • High Prevalence and Increased Severity of Pathology of Bovine Tuberculosis in Holsteins Compared to Zebu Breeds under Field Cattle Husbandry in Central Ethiopia

    Gobena Ameni;Abraham Aseffa;Howard Engers;Douglas Young

  • Ecotypes of the Mycobacterium tuberculosis complex

    Noel H. Smith;Kristin Kremer;Jacqueline Inwald;James Dale

  • Molecular Analysis of Human and Bovine Tubercle Bacilli from a Local Setting in Nigeria

    Simeon Cadmus;Si Palmer;Melissa Okker;James Dale

  • Circulating microRNAs as Potential Biomarkers of Infectious Disease.

    Carolina N. Correia;Nicolas C. Nalpas;Kirsten E. McLoughlin;John A. Browne

Frequent Co-Authors

Stewart T. Cole
Stewart T. Cole Institut Pasteur
R. Glyn Hewinson
R. Glyn Hewinson Aberystwyth University
Roland Brosch
Roland Brosch Institut Pasteur
David E. MacHugh
David E. MacHugh University College Dublin
Abraham Aseffa
Abraham Aseffa Armauer Hansen Research Institute
Eamonn Gormley
Eamonn Gormley University College Dublin
Gobena Ameni
Gobena Ameni United Arab Emirates University
Bart Barrell
Bart Barrell Wellcome Sanger Institute
Paul R. Crocker
Paul R. Crocker University of Dundee

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