D-Index & Metrics Best Publications
Microbiology
UK
2023

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Microbiology D-index 99 Citations 26,885 209 World Ranking 241 National Ranking 28

Research.com Recognitions

Awards & Achievements

2023 - Research.com Microbiology in United Kingdom Leader Award

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Immune system
  • Biochemistry

Paul R. Crocker spends much of his time researching Sialic Acid Binding Immunoglobulin-like Lectins, SIGLEC, Biochemistry, Molecular biology and Sialoadhesin. His work carried out in the field of Sialic Acid Binding Immunoglobulin-like Lectins brings together such families of science as Immune system, COS cells, Immunoglobulin superfamily and Cell biology. Paul R. Crocker interconnects Interleukin 12, Lymphokine-activated killer cell and Ganglioside GD3 in the investigation of issues within SIGLEC.

His study in Biochemistry is interdisciplinary in nature, drawing from both Selectin and Cell adhesion molecule. His studies in Molecular biology integrate themes in fields like Stromal cell, Janus kinase 3, Point mutation and Fragment crystallizable region. His Sialoadhesin study incorporates themes from Immunoglobulin domain, Glycoprotein, Cell adhesion, Cell surface receptor and Cell–cell interaction.

His most cited work include:

  • Siglecs and their roles in the immune system (1242 citations)
  • A novel role for myelin-associated glycoprotein as an inhibitor of axonal regeneration (975 citations)
  • Siglec-mediated regulation of immune cell function in disease (460 citations)

What are the main themes of his work throughout his whole career to date?

His main research concerns SIGLEC, Sialoadhesin, Biochemistry, Cell biology and Immunology. His SIGLEC research includes themes of Innate immune system, Stereochemistry, Sialic Acid Binding Immunoglobulin-like Lectins and Glycan. His Sialic Acid Binding Immunoglobulin-like Lectins research incorporates themes from COS cells and Immunoglobulin superfamily.

His biological study spans a wide range of topics, including Glycoprotein, Molecular biology, Sialic acid binding, Marginal zone and Spleen. The study incorporates disciplines such as CD22 and Cell adhesion molecule in addition to Biochemistry. As a part of the same scientific study, Paul R. Crocker usually deals with the Cell biology, concentrating on Macrophage and frequently concerns with Bone marrow.

He most often published in these fields:

  • SIGLEC (45.66%)
  • Sialoadhesin (36.23%)
  • Biochemistry (33.21%)

What were the highlights of his more recent work (between 2013-2021)?

  • SIGLEC (45.66%)
  • Cell biology (28.68%)
  • Immunology (23.40%)

In recent papers he was focusing on the following fields of study:

His primary areas of study are SIGLEC, Cell biology, Immunology, Immune system and Macrophage. His SIGLEC study is related to the wider topic of Sialic acid. His research in Cell biology intersects with topics in Cell, Receptor, Sialic acid binding, T cell and Glycosylation.

In general Immunology, his work in Inflammation, Immunosurveillance, Lymphocyte and Microglia is often linked to Interleukin 23 linking many areas of study. His Immune system study combines topics from a wide range of disciplines, such as Cancer, Antigen, Glycan, Antibody and In vivo. While the research belongs to areas of Sialoadhesin, Paul R. Crocker spends his time largely on the problem of Spleen, intersecting his research to questions surrounding Marginal zone.

Between 2013 and 2021, his most popular works were:

  • Siglec-mediated regulation of immune cell function in disease (460 citations)
  • CD169 mediates the capture of exosomes in spleen and lymph node (202 citations)
  • The mucin MUC1 modulates the tumor immunological microenvironment through engagement of the lectin Siglec-9 (112 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Immune system
  • Antibody

The scientist’s investigation covers issues in Immunology, Cell biology, SIGLEC, Inflammation and Microbiology. He usually deals with Immunology and limits it to topics linked to Parenchyma and Cell adhesion, C-C chemokine receptor type 6, Lymph, Immunity and Choroid plexus. The various areas that Paul R. Crocker examines in his Cell biology study include Cellular differentiation, Calcium flux, T cell, CD8 and Sialoadhesin.

His work in Sialoadhesin tackles topics such as Cytotoxic T cell which are related to areas like Dendritic cell. His SIGLEC research includes elements of Perivascular space, Tumor microenvironment, Cancer cell, Integrin alpha M and Microglia. His research integrates issues of Receptor, Signal transduction, Sialic Acid Binding Immunoglobulin-like Lectins and Glycan in his study of Immune system.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Siglecs and their roles in the immune system

Paul R. Crocker;James C. Paulson;Ajit Varki.
Nature Reviews Immunology (2007)

1879 Citations

A novel role for myelin-associated glycoprotein as an inhibitor of axonal regeneration

Gitali Mukhopadhyay;Patrick Doherty;Frank S. Walsh;Paul R. Crocker.
Neuron (1994)

1375 Citations

Siglec-mediated regulation of immune cell function in disease

Matthew S. Macauley;Paul R. Crocker;James C. Paulson.
Nature Reviews Immunology (2014)

759 Citations

Siglecs, sialic acids and innate immunity

Paul R. Crocker;Ajit Varki.
Trends in Immunology (2001)

504 Citations

Sialoadhesin, myelin-associated glycoprotein and CD22 define a new family of sialic acid-dependent adhesion molecules of the immunoglobulin superfamily

Sørge Kelm;Andrea Pelz;Roland Schauer;Marie T. Filbin.
Current Biology (1994)

491 Citations

Siglecs: sialic-acid-binding immunoglobulin-like lectins in cell-cell interactions and signalling.

Paul R Crocker.
Current Opinion in Structural Biology (2002)

400 Citations

Carbohydrate recognition systems: functional triads in cell—cell interactions

Paul R Crocker;Ten Feizi.
Current Opinion in Structural Biology (1996)

390 Citations

Characterization of CD33 as a new member of the sialoadhesin family of cellular interaction molecules

SD Freeman;S Kelm;EK Barber;PR Crocker.
Blood (1995)

380 Citations

Characterization of human sialoadhesin, a sialic acid binding receptor expressed by resident and inflammatory macrophage populations

Adele Hartnell;Jane Steel;Helen Turley;Margaret Jones.
Blood (2001)

336 Citations

Isolation of the gene for McLeod syndrome that encodes a novel membrane transport protein

Mengfatt Ho;Jamel Chelly;Nick Carter;Adrian Danek.
Cell (1994)

332 Citations

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