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D-Index & Metrics

Microbiology

D-Index
105
Citations
31020
World Ranking
321
National Ranking
40

Overview

Paul R. Crocker is affiliated with the University of Dundee in the United Kingdom and has a research focus primarily situated within the fields of Biochemistry, Genetics and Molecular Biology, Immunology and Microbiology, and Medicine. Their work spans several subfields including Molecular Biology, Immunology, Radiology, Nuclear Medicine and Imaging, Cell Biology, and Organic Chemistry.

The scientist's main research topics include Glycosylation and Glycoproteins Research, Galectins and Cancer Biology, Monoclonal and Polyclonal Antibodies Research, Immune cells in cancer, Proteoglycans and glycosaminoglycans research, Carbohydrate Chemistry and Synthesis, and Cell Adhesion Molecules Research. These topics reflect a broad engagement with molecular and cellular processes relevant to cancer biology and immunology.

Among their recent publications are the following papers:

  • Siglec and anti-Siglec therapies, 2021, Current Opinion in Chemical Biology
  • Siglec-15 recognition of sialoglycans on tumor cell lines can occur independently of sialyl Tn antigen expression, 2020, Glycobiology
  • Siglec-7 Mediates Immunomodulation by Colorectal Cancer-Associated Fusobacterium nucleatum ssp. animalis, 2021, Frontiers in Immunology
  • Discovery of a new sialic acid binding region that regulates Siglec-7, 2020, Scientific Reports
  • Unveiling Molecular Recognition of Sialoglycans by Human Siglec-10, 2020, iScience

The top publication venues where Paul R. Crocker frequently publishes include:

  • iScience
  • Wellcome Open Research
  • Current Opinion in Chemical Biology
  • Frontiers in Immunology
  • Glycobiology

Paul R. Crocker collaborates often with a group of co-authors with whom they have multiple joint publications. Frequent co-authors include Roberta Marchetti, Alba Silipo, Gavuthami Murugesan, Rosa Ester Forgione, and Cristina Di Carluccio.

Best Publications

  • Siglecs and their roles in the immune system

    Paul R. Crocker;James C. Paulson;Ajit Varki

  • A novel role for myelin-associated glycoprotein as an inhibitor of axonal regeneration

    Gitali Mukhopadhyay;Patrick Doherty;Frank S. Walsh;Paul R. Crocker

  • Siglec-mediated regulation of immune cell function in disease

    Matthew S. Macauley;Paul R. Crocker;James C. Paulson

  • Siglecs, sialic acids and innate immunity

    Paul R. Crocker;Ajit Varki

  • Sialoadhesin, myelin-associated glycoprotein and CD22 define a new family of sialic acid-dependent adhesion molecules of the immunoglobulin superfamily

    Sørge Kelm;Andrea Pelz;Roland Schauer;Marie T. Filbin

  • Siglecs: sialic-acid-binding immunoglobulin-like lectins in cell-cell interactions and signalling.

    Paul R Crocker

  • CD169 mediates the capture of exosomes in spleen and lymph node

    Sarah C. Saunderson;Amy C. Dunn;Paul R. Crocker;Alexander D. McLellan

  • Characterization of CD33 as a new member of the sialoadhesin family of cellular interaction molecules

    SD Freeman;S Kelm;EK Barber;PR Crocker

  • Carbohydrate recognition systems: functional triads in cell—cell interactions

    Paul R Crocker;Ten Feizi

  • The mucin MUC1 modulates the tumor immunological microenvironment through engagement of the lectin Siglec-9

    Richard Beatson;Virginia Tajadura-Ortega;Daniela Yordanova Achkova;Gianfranco Picco

  • Characterization of human sialoadhesin, a sialic acid binding receptor expressed by resident and inflammatory macrophage populations

    Adele Hartnell;Jane Steel;Helen Turley;Margaret Jones

  • Sialoside Specificity of the Siglec Family Assessed Using Novel Multivalent Probes IDENTIFICATION OF POTENT INHIBITORS OF MYELIN-ASSOCIATED GLYCOPROTEIN

    Ola Blixt;Brian E. Collins;Ingrid M. van den Nieuwenhof;Paul R. Crocker;Paul R. Crocker

  • Siglecs in the immune system.

    Paul R. Crocker;Ajit Varki

  • Purification and properties of sialoadhesin, a sialic acid-binding receptor of murine tissue macrophages

    P.R. Crocker;S. Kelm;C. Dubois;B. Martin

  • Crystal structure of the N-terminal domain of sialoadhesin in complex with 3' sialyllactose at 1.85 A resolution.

    A.P. May;R.C. Robinson;M. Vinson;P.R. Crocker

  • Sialoadhesin, a macrophage sialic acid binding receptor for haemopoietic cells with 17 immunoglobulin-like domains.

    P.R. Crocker;S. Mucklow;V. Bouckson;A.S. Mcwilliam

  • Identification and Characterization of a Novel Siglec, Siglec-7, Expressed by Human Natural Killer Cells and Monocytes

    Gavin Nicoll;Jian Ni;Ding Liu;Paul Klenerman

  • Isolation and characterization of resident stromal macrophages and hematopoietic cell clusters from mouse bone marrow.

    P R Crocker;S Gordon

  • Characterization of Siglec-H as a novel endocytic receptor expressed on murine plasmacytoid dendritic cell precursors.

    Jiquan Zhang;Anna Raper;Noriko Sugita;Ravi Hingorani

  • Mouse macrophage hemagglutinin (sheep erythrocyte receptor) with specificity for sialylated glycoconjugates characterized by a monoclonal antibody.

    P R Crocker;S Gordon

Frequent Co-Authors

Siamon Gordon
Siamon Gordon University of Oxford
Nicolai V. Bovin
Nicolai V. Bovin Russian Academy of Sciences
James C. Paulson
James C. Paulson Scripps Research Institute
Bruce S. Bochner
Bruce S. Bochner Northwestern University
Ajit Varki
Ajit Varki University of California, San Diego
Ronald L. Schnaar
Ronald L. Schnaar Johns Hopkins University School of Medicine
Lynn Morris
Lynn Morris University of the Witwatersrand
Stephen V. Gordon
Stephen V. Gordon University College Dublin
Jian Ni
Jian Ni Zhejiang Normal University
Robert A. Field
Robert A. Field University of Manchester

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