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Biology and Biochemistry

D-Index
81
Citations
26395
World Ranking
3847
National Ranking
1906

Overview

Ronald L. Schnaar is affiliated with Johns Hopkins University School of Medicine in the United States. Their research primarily spans across several fields including biochemistry, genetics and molecular biology, medicine, and immunology and microbiology.

The scientist's subfields of study include molecular biology, immunology, cell biology, physiology, and cellular and molecular neuroscience. The main topics of their work focus on glycosylation and glycoproteins research, galectins and cancer biology, proteoglycans and glycosaminoglycans research, neuroinflammation and neurodegeneration mechanisms, carbohydrate chemistry and synthesis, asthma and respiratory diseases, and Alzheimer's disease research and treatments.

Ronald L. Schnaar has contributed to various publication venues with notable frequency, including:

  • Glycobiology
  • Journal of Biological Chemistry
  • International Journal of Molecular Sciences
  • Journal of Visualized Experiments
  • Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Among recent papers involving Ronald L. Schnaar, key publications include:

  • Probing the binding specificities of human Siglecs by cell-based glycan arrays (2021), published in Proceedings of the National Academy of Sciences
  • Siglec Ligands (2021), published in Cells
  • Human brain sialoglycan ligand for CD33, a microglial inhibitory Siglec implicated in Alzheimer's disease (2022), published in Journal of Biological Chemistry
  • Discovery and Classification of Glycan-Binding Proteins (2022), published in HAL (Le Centre pour la Communication Scientifique Directe)
  • Amyloid-beta and tau pathologies act synergistically to induce novel disease stage-specific microglia subtypes (2022), published in Molecular Neurodegeneration

Frequent co-authors working with Ronald L. Schnaar include Anabel Gonzalez-Gil, Steve M. Fernandes, Benjamin C. Orsburn, Ryan N. Porell, and T August Li. These collaborations highlight involvement in interdisciplinary studies related to cellular and molecular mechanisms.

Best Publications

  • Essentials of Glycobiology [Internet]

    Ajit Varki;Richard D Cummings;Jeffrey D Esko;Pamela Stanley

  • Glutamate toxicity in a neuronal cell line involves inhibition of cystine transport leading to oxidative stress

    Timothy H. Murphy;Masaomi Miyamoto;Antonio Sastre;Ronald L. Schnaar

  • Symbol Nomenclature for Graphical Representations of Glycans.

    Ajit Varki;Richard D. Cummings;Markus Aebi;Nicole H. Packer

  • Sialic Acids in the Brain: Gangliosides and Polysialic Acid in Nervous System Development, Stability, Disease, and Regeneration

    Ronald L. Schnaar;Rita Gerardy-Schahn;Rita Gerardy-Schahn;Herbert Hildebrandt;Herbert Hildebrandt

  • Immature cortical neurons are uniquely sensitive to glutamate toxicity by inhibition of cystine uptake.

    Timothy H. Murphy;Ronald L. Schnaar;Joseph T. Coyle

  • Sialoadhesin, myelin-associated glycoprotein and CD22 define a new family of sialic acid-dependent adhesion molecules of the immunoglobulin superfamily

    Sørge Kelm;Andrea Pelz;Roland Schauer;Marie T. Filbin

  • Mice lacking complex gangliosides develop Wallerian degeneration and myelination defects

    Kazim A. Sheikh;Ji Sun;Yujing Liu;Hiromichi Kawai

  • Updates to the Symbol Nomenclature for Glycans guidelines.

    Sriram Neelamegham;Kiyoko Aoki-Kinoshita;Evan Bolton;Martin Frank

  • Gangliosides are neuronal ligands for myelin-associated glycoprotein.

    Lynda J.S. Yang;Cynthia B. Zeller;Nancy L. Shaper;Makoto Kiso

  • Gangliosides in cell recognition and membrane protein regulation

    Pablo H H Lopez;Ronald L Schnaar

  • Gangliosides are functional nerve cell ligands for myelin-associated glycoprotein (MAG), an inhibitor of nerve regeneration.

    Alka A. Vyas;Himatkumar V. Patel;Susan E. Fromholt;Marija Heffer-Lauc

  • Antioxidants protect against glutamate-induced cytotoxicity in a neuronal cell line.

    M Miyamoto;T H Murphy;R L Schnaar;J T Coyle

  • Glycan Array Screening Reveals a Candidate Ligand for Siglec-8

    Bruce S. Bochner;Richard A. Alvarez;Padmaja Mehta;Nicolai V. Bovin

  • Cell-surface carbohydrates in cell recognition and response.

    Brian K. Brandley;Ronald L. Schnaar

  • Siglecs: a family of sialic-acid binding lectins.

    P R Crocker;E A Clark;M Filbin;S Gordon

  • Myelin-associated glycoprotein and complementary axonal ligands, gangliosides, mediate axon stability in the CNS and PNS: neuropathology and behavioral deficits in single- and double-null mice.

    Baohan Pan;Susan E. Fromholt;Ellen J. Hess;Thomas O. Crawford

  • Covalent attachment of an Arg-Gly-Asp sequece peptide to derivatizable polyacrylamide surfaces: Support of fibroblast adhesion and long-term growth☆

    Brian K. Brandley;Ronald L. Schnaar

  • The HNK-1 reactive sulfoglucuronyl glycolipids are ligands for L-selectin and P-selectin but not E-selectin.

    Leila K. Needham;Ronald L. Schnaar

  • Carcinoembryonic Antigen and CD44 Variant Isoforms Cooperate to Mediate Colon Carcinoma Cell Adhesion to E- and L-selectin in Shear Flow

    Susan N. Thomas;Fei Zhu;Ronald L. Schnaar;Christina S. Alves

  • Sialic acid specificity of myelin-associated glycoprotein binding.

    Brian E. Collins;Lynda J.-S. Yang;Gitali Mukhopadhyay;Marie T. Filbin

Frequent Co-Authors

Bruce S. Bochner
Bruce S. Bochner Northwestern University
Joseph T. Coyle
Joseph T. Coyle Harvard University
Paul R. Crocker
Paul R. Crocker University of Dundee
Gerald W. Hart
Gerald W. Hart University of Georgia
Ajit Varki
Ajit Varki University of California, San Diego
Konstantinos Konstantopoulos
Konstantinos Konstantopoulos Johns Hopkins University
James C. Paulson
James C. Paulson Scripps Research Institute
Makoto Kiso
Makoto Kiso Gifu University
Leonardo Nimrichter
Leonardo Nimrichter Federal University of Rio de Janeiro
Yuan C. Lee
Yuan C. Lee Johns Hopkins University

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