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Biology and Biochemistry

D-Index
48
Citations
15240
World Ranking
18204
National Ranking
7439

Research.com Recognitions

  • 2011 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Marie T. Filbin was affiliated with the City University of New York in the United States. Their research focused primarily on neuroscience and biochemistry, genetics, and molecular biology, with a strong emphasis on cellular and molecular neuroscience.

The researcher's work covered key topics including nerve injury and regeneration, signaling pathways in disease, axon guidance and neuronal signaling, neuroinflammation and neurodegeneration mechanisms, and neurogenesis and neuroplasticity mechanisms.

Marie T. Filbin authored several papers addressing various aspects of these topics. Notable publications include:

  • Extracellular histones, a new class of inhibitory molecules of CNS axonal regeneration (2021), published in Brain Communications
  • Myelin-associated glycoprotein inhibits neurite outgrowth through inactivation of the small GTPase Rap1 (2020), published in FEBS Letters
  • A spatially specified systems pharmacology therapy for axonal recovery after injury (2023), published in Frontiers in Pharmacology

Their research was often conducted in collaboration with several frequent co-authors:

  • Mustafa M. Siddiq
  • Sari S. Hannila
  • Yana Zorina
  • Elena Nikulina
  • Vera Rabinovich

Marie T. Filbin's publications appeared primarily in the journals Brain Communications, FEBS Letters, and Frontiers in Pharmacology. These venues complement their focus on cellular and molecular mechanisms related to neuronal injury and recovery.

In recognition of their contributions to the scientific community, Marie T. Filbin was named a Fellow of the American Association for the Advancement of Science (AAAS) in 2011.

Best Publications

  • A novel role for myelin-associated glycoprotein as an inhibitor of axonal regeneration

    Gitali Mukhopadhyay;Patrick Doherty;Frank S. Walsh;Paul R. Crocker

  • Myelin-associated inhibitors of axonal regeneration in the adult mammalian CNS

    Marie T. Filbin

  • cAMP and Schwann cells promote axonal growth and functional recovery after spinal cord injury

    Damien P. Pearse;Francisco Carlos Pereira;Alexander E. Marcillo;Margaret L. Bates

  • Spinal axon regeneration induced by elevation of cyclic AMP.

    Jin Qiu;Dongming Cai;Haining Dai;Marietta McAtee

  • Myelin-associated glycoprotein interacts with the Nogo66 receptor to inhibit neurite outgrowth.

    Marco Domeniconi;Zixuan Cao;Timothy Spencer;Rajeev Sivasankaran

  • Neuronal cyclic AMP controls the developmental loss in ability of axons to regenerate.

    Dongming Cai;Jin Qiu;Zixuan Cao;Marietta McAtee

  • Prior Exposure to Neurotrophins Blocks Inhibition of Axonal Regeneration by MAG and Myelin via a cAMP-Dependent Mechanism

    Dongming Cai;Yingjing Shen;MariaElena De Bellard;Song Tang

  • Sialoadhesin, myelin-associated glycoprotein and CD22 define a new family of sialic acid-dependent adhesion molecules of the immunoglobulin superfamily

    Sørge Kelm;Andrea Pelz;Roland Schauer;Marie T. Filbin

  • Combinatorial Therapy with Neurotrophins and cAMP Promotes Axonal Regeneration beyond Sites of Spinal Cord Injury

    Paul Lu;Hong Yang;Leonard L. Jones;Marie T. Filbin

  • The phosphodiesterase inhibitor rolipram delivered after a spinal cord lesion promotes axonal regeneration and functional recovery.

    Elena Nikulina;J. Lille Tidwell;Hai Ning Dai;Barbara S. Bregman

  • Activated CREB Is Sufficient to Overcome Inhibitors in Myelin and Promote Spinal Axon Regeneration In Vivo

    Ying Gao;Kangwen Deng;Jianwei Hou;J.Barney Bryson

  • The role of cyclic AMP signaling in promoting axonal regeneration after spinal cord injury.

    Sari S. Hannila;Marie T. Filbin

  • Arginase I and Polyamines Act Downstream from Cyclic AMP in Overcoming Inhibition of Axonal Growth MAG and Myelin In Vitro

    Dongming Cai;Kangwen Deng;Wilfredo Mellado;Junghee Lee

  • Siglecs: a family of sialic-acid binding lectins.

    P R Crocker;E A Clark;M Filbin;S Gordon

  • Neurotrophins elevate cAMP to reach a threshold required to overcome inhibition by MAG through extracellular signal-regulated kinase-dependent inhibition of phosphodiesterase.

    Ying Gao;Elena Nikulina;Wilfredo Mellado;Marie T. Filbin

  • Myelin-Associated Glycoprotein Inhibits Axonal Regeneration from a Variety of Neurons via Interaction with a Sialoglycoprotein

    Maria-Elena DeBellard;Song Tang;Gitali Mukhopadhyay;Ying-Jing Shen

  • Combined Intrinsic and Extrinsic Neuronal Mechanisms Facilitate Bridging Axonal Regeneration One Year after Spinal Cord Injury

    Ken Kadoya;Shingo Tsukada;Paul Lu;Paul Lu;Giovanni Coppola

  • MAG induces regulated intramembrane proteolysis of the p75 neurotrophin receptor to inhibit neurite outgrowth.

    Marco Domeniconi;Niccolò Zampieri;Tim Spencer;Melissa Hilaire

  • Sialic acid specificity of myelin-associated glycoprotein binding.

    Brian E. Collins;Lynda J.-S. Yang;Gitali Mukhopadhyay;Marie T. Filbin

  • Correction: Myelin-associated inhibitors of axonal regeneration in the adult mammalian CNS

    Marie T. Filbin

Frequent Co-Authors

Rajiv R. Ratan
Rajiv R. Ratan Cornell University
Ravi Iyengar
Ravi Iyengar Icahn School of Medicine at Mount Sinai
Paul R. Crocker
Paul R. Crocker University of Dundee
Mark H. Tuszynski
Mark H. Tuszynski University of California, San Diego
Ronald L. Schnaar
Ronald L. Schnaar Johns Hopkins University School of Medicine
Brent R. Stockwell
Brent R. Stockwell Columbia University
Robert Sebra
Robert Sebra Icahn School of Medicine at Mount Sinai
Barbara S. Bregman
Barbara S. Bregman Georgetown University Medical Center
Ronald P. Hart
Ronald P. Hart Rutgers, The State University of New Jersey
Christopher E. Henderson
Christopher E. Henderson Biogen (United States)

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