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Neuroscience

D-Index
114
Citations
41118
World Ranking
473
National Ranking
275

Overview

Mark H. Tuszynski is affiliated with the University of California, San Diego in the United States. Their research activity is primarily centered in the fields of Neuroscience and Medicine, with a significant focus on Cellular and Molecular Neuroscience, Developmental Neuroscience, Molecular Biology, Pathology and Forensic Medicine, and Surgery.

The scientist's work extensively covers topics such as neurogenesis and neuroplasticity mechanisms, nerve injury and regeneration, spinal cord injury research, neuroscience and neural engineering, tissue engineering and regenerative medicine, nerve injury and rehabilitation, and spinal dysraphism and malformations.

Mark H. Tuszynski has contributed to numerous publications across a variety of academic venues. Frequent publication outlets include Experimental Neurology, Nature, Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature, Nature Reviews Molecular Cell Biology, and Cell Stem Cell.

Their recent papers include the following:

  • Injured adult neurons regress to an embryonic transcriptional growth state, 2020, Nature
  • Regulation of axonal regeneration after mammalian spinal cord injury, 2023, Nature Reviews Molecular Cell Biology
  • Neural Stem Cell Grafts Form Extensive Synaptic Networks that Integrate with Host Circuits after Spinal Cord Injury, 2020, Cell Stem Cell
  • Postmortem Analysis in a Clinical Trial of AAV2-NGF Gene Therapy for Alzheimer's Disease Identifies a Need for Improved Vector Delivery, 2020, Human Gene Therapy
  • Rhesus macaque versus rat divergence in the corticospinal projectome, 2022, Neuron

Collaboration is an integral part of their scholarly activities. Frequent co-authors include E Rosenzweig, Paul Lu, Michael S. Beattie, Lori Graham, and Jacqueline C. Bresnahan.

Best Publications

  • Neural stem cells constitutively secrete neurotrophic factors and promote extensive host axonal growth after spinal cord injury

    P Lu;L.L Jones;E.Y Snyder;M.H Tuszynski;M.H Tuszynski

  • Neuroprotective effects of brain-derived neurotrophic factor in rodent and primate models of Alzheimer's disease

    Alan H Nagahara;David A Merrill;Giovanni Coppola;Shingo Tsukada

  • A phase 1 clinical trial of nerve growth factor gene therapy for Alzheimer disease

    Mark H Tuszynski;Mark H Tuszynski;Leon Thal;Leon Thal;Mary Pay;David P Salmon

  • A shared neural ensemble links distinct contextual memories encoded close in time

    Denise J. Cai;Daniel Aharoni;Daniel Aharoni;Tristan Shuman;Justin Shobe

  • Potential therapeutic uses of BDNF in neurological and psychiatric disorders

    Alan H. Nagahara;Mark H. Tuszynski;Mark H. Tuszynski

  • Long-Distance Growth and Connectivity of Neural Stem Cells after Severe Spinal Cord Injury

    Paul Lu;Yaozhi Wang;Lori Graham;Karla McHale

  • Cellular Delivery of Neurotrophin-3 Promotes Corticospinal Axonal Growth and Partial Functional Recovery after Spinal Cord Injury

    R. Grill;K. Murai;A. Blesch;F. H. Gage

  • Guidelines for the conduct of clinical trials for spinal cord injury as developed by the ICCP panel: spontaneous recovery after spinal cord injury and statistical power needed for therapeutic clinical trials

    J W Fawcett;A Curt;J D Steeves;W P Coleman

  • The chondroitin sulfate proteoglycans neurocan, brevican, phosphacan, and versican are differentially regulated following spinal cord injury.

    Leonard L Jones;Richard U Margolis;Mark H Tuszynski;Mark H Tuszynski

  • Biomimetic 3D-printed scaffolds for spinal cord injury repair

    Jacob Koffler;Wei Zhu;Xin Qu;Oleksandr Platoshyn

  • INDUCTION OF BONE MARROW STROMAL CELLS TO NEURONS: DIFFERENTIATION, TRANSDIFFERENTIATION, OR ARTIFACT?

    Paul Lu;Armin Blesch;Mark H. Tuszynski;Mark H. Tuszynski

  • Spontaneous corticospinal axonal plasticity and functional recovery after adult central nervous system injury.

    Norbert Weidner;Arvin Ner;Nima Salimi;Mark H. Tuszynski

  • NG2 Is a Major Chondroitin Sulfate Proteoglycan Produced after Spinal Cord Injury and Is Expressed by Macrophages and Oligodendrocyte Progenitors

    Leonard L. Jones;Yu Yamaguchi;William B. Stallcup;Mark H. Tuszynski;Mark H. Tuszynski

  • Grafting genetically modified cells to the damaged brain: restorative effects of NGF expression

    Michael B. Rosenberg;Theodore Friedmann;Robin C. Robertson;Mark Tuszynski

  • BDNF-expressing marrow stromal cells support extensive axonal growth at sites of spinal cord injury

    P. Lu;L.L. Jones;M.H. Tuszynski;M.H. Tuszynski

  • Guidelines for the conduct of clinical trials for spinal cord injury (SCI) as developed by the ICCP panel: clinical trial outcome measures

    J. D. Steeves;D. Lammertse;A. Curt;J. W. Fawcett

  • Combinatorial Therapy with Neurotrophins and cAMP Promotes Axonal Regeneration beyond Sites of Spinal Cord Injury

    Paul Lu;Hong Yang;Leonard L. Jones;Marie T. Filbin

  • Extensive spontaneous plasticity of corticospinal projections after primate spinal cord injury

    Ephron S Rosenzweig;Gregoire Courtine;Gregoire Courtine;Devin L Jindrich;John H Brock

  • Lesions of the Basal Forebrain Cholinergic System Impair Task Acquisition and Abolish Cortical Plasticity Associated with Motor Skill Learning

    James M Conner;Andrew Culberson;Christine Packowski;Andrea A Chiba

  • Freeze-dried agarose scaffolds with uniaxial channels stimulate and guide linear axonal growth following spinal cord injury

    Shula Stokols;Mark H. Tuszynski;Mark H. Tuszynski

Frequent Co-Authors

Armin Blesch
Armin Blesch Indiana University
James M. Conner
James M. Conner University of California, San Diego
Fred H. Gage
Fred H. Gage Salk Institute for Biological Studies
Leif A. Havton
Leif A. Havton Icahn School of Medicine at Mount Sinai
Jeff Sakamoto
Jeff Sakamoto University of Michigan–Ann Arbor
Adam R. Ferguson
Adam R. Ferguson University of California, San Francisco
Jacqueline C. Bresnahan
Jacqueline C. Bresnahan University of California, San Francisco
Grégoire Courtine
Grégoire Courtine École Polytechnique Fédérale de Lausanne
Michael S. Beattie
Michael S. Beattie University of California, San Francisco
James W. Fawcett
James W. Fawcett University of Cambridge

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