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Neuroscience

D-Index
74
Citations
15997
World Ranking
2141
National Ranking
1016

Overview

Itzhak Fischer is affiliated with Drexel University in the United States. Their research spans several disciplines, primarily focusing on neuroscience, medicine, and biochemistry, genetics and molecular biology. Within these fields, Fischer's work concentrates on subfields such as cellular and molecular neuroscience, molecular biology, physiology, developmental neuroscience, and surgery.

Fischer's recent scholarly contributions include the following papers:

  • Transplanting neural progenitor cells to restore connectivity after spinal cord injury (2020), published in Nature Reviews. Neuroscience
  • Resurrecting the Mysteries of Big Tau (2020), published in Trends in Neurosciences

These publications indicate a focus on neural repair mechanisms and molecular neuroscience.

The scientist frequently collaborates with other researchers. Prominent co-authors include:

  • Ying Jin
  • Julien Bouyer
  • Peter A. Galie
  • Theresa Connors
  • Michael A. Lane

These collaborations reflect an interdisciplinary approach spanning bioengineering and neurobiology.

Fischer's work appears often in publication venues such as Cytoskeleton, bioRxiv (Cold Spring Harbor Laboratory), Biomaterials, Frontiers in Molecular Neuroscience, and Journal of Medicinal Chemistry. This variety of venues underscores contributions to both fundamental and applied biosciences.

The main topics covered in Fischer's research include:

  • Alzheimer's disease research and treatments
  • Nerve injury and regeneration
  • Neuroscience and neuropharmacology research
  • Neurogenesis and neuroplasticity mechanisms
  • Tissue engineering and regenerative medicine
  • Pluripotent stem cells research
  • Retinal development and disorders

These topics illustrate a broad engagement with neurodegenerative diseases, neural repair, and regenerative strategies.

Overall, Fischer's contributions demonstrate a clear concentration in neuroscience and regenerative medicine, covering both cellular and molecular aspects of neural tissues. Their work provides insights into neural connectivity restoration and molecular mechanisms involved in neurobiology.

Best Publications

  • In vitro differentiation of human marrow stromal cells into early progenitors of neural cells by conditions that increase intracellular cyclic AMP.

    Weiwen Deng;Maria Obrocka;Itzhak Fischer;Darwin J. Prockop

  • Transplants of Fibroblasts Genetically Modified to Express BDNF Promote Regeneration of Adult Rat Rubrospinal Axons and Recovery of Forelimb Function

    Yi Liu;Duckhyun Kim;B. Timothy Himes;B. Timothy Himes;Stella Y. Chow

  • Reevaluation of in vitro differentiation protocols for bone marrow stromal cells: disruption of actin cytoskeleton induces rapid morphological changes and mimics neuronal phenotype.

    Birgit Neuhuber;Gianluca Gallo;Linda Howard;Lisa Kostura

  • Axon growth and recovery of function supported by human bone marrow stromal cells in the injured spinal cord exhibit donor variations.

    Birgit Neuhuber;B. Timothy Himes;B. Timothy Himes;Jed S. Shumsky;Gianluca Gallo

  • Tau Is Enriched on Dynamic Microtubules in the Distal Region of Growing Axons

    Mark M. Black;Theresa Slaughter;Simon Moshiach;Maria Obrocka

  • Recovery of Function Following Grafting of Human Bone Marrow-Derived Stromal Cells into the Injured Spinal Cord

    B. Timothy Himes;Birgit Neuhuber;Carl Coleman;Robert Kushner

  • EFFECTS OF PLATING DENSITY AND CULTURE TIME ON BONE MARROW STROMAL CELL CHARACTERISTICS

    Birgit Neuhuber;Sharon A. Swanger;Linda Howard;Alastair Mackay

  • Delayed grafting of BDNF and NT-3 producing fibroblasts into the injured spinal cord stimulates sprouting, partially rescues axotomized red nucleus neurons from loss and atrophy, and provides limited regeneration

    C.A Tobias;J.S Shumsky;M Shibata;M.H Tuszynski

  • Transplanting neural progenitor cells to restore connectivity after spinal cord injury.

    Itzhak Fischer;Jennifer N. Dulin;Michael A. Lane

  • CD44 expression identifies astrocyte-restricted precursor cells

    Ying Liu;Ying Liu;Steve S.W. Han;Yuanyuan Wu;Therese M.F. Tuohy

  • Grafted Neural Progenitors Integrate and Restore Synaptic Connectivity across the Injured Spinal Cord

    Joseph F. Bonner;Theresa M. Connors;William F. Silverman;David P. Kowalski

  • Transplantation of Neuronal and Glial Restricted Precursors into Contused Spinal Cord Improves Bladder and Motor Functions, Decreases Thermal Hypersensitivity, and Modifies Intraspinal Circuitry

    Takahiko Mitsui;Jed S. Shumsky;Angelo C. Lepore;Marion Murray

  • Transplants of Fibroblasts Genetically Modified to Express BDNF Promote Axonal Regeneration from Supraspinal Neurons Following Chronic Spinal Cord Injury

    Ying Jin;Itzhak Fischer;Alan Tessler;John D. Houle

  • Neural stem cells may be uniquely suited for combined gene therapy and cell replacement: Evidence from engraftment of Neurotrophin-3-expressing stem cells in hypoxic-ischemic brain injury.

    Kook In Park;B. Timothy Himes;B. Timothy Himes;Philip E. Stieg;Alan Tessler;Alan Tessler

  • Peptide-modified alginate surfaces as a growth permissive substrate for neurite outgrowth.

    Nikhil O. Dhoot;Chris A. Tobias;Itzhak Fischer;Margaret A. Wheatley

  • Intraspinal delivery of neurotrophin-3 using neural stem cells genetically modified by recombinant retrovirus.

    Y. Liu;B. T. Himes;B. T. Himes;J. Solowska;J. Moul

  • Grafting of human bone marrow stromal cells into spinal cord injury: a comparison of delivery methods.

    Courtney Paul;Amer F. Samdani;Randal R. Betz;Itzhak Fischer

  • Lineage-restricted neural precursors survive, migrate, and differentiate following transplantation into the injured adult spinal cord.

    A.C. Lepore;I. Fischer

  • The limbic system-associated membrane protein is an Ig superfamily member that mediates selective neuronal growth and axon targeting.

    Aurea F. Pimenta;Victoria Zhukareva;Mary F. Barbe;Blesilda S. Reinoso

  • Mechanically engineered hydrogel scaffolds for axonal growth and angiogenesis after transplantation in spinal cord injury.

    Ajay Bakshi;Omar Fisher;Taner Dagci;B Timothy Himes

  • Characterization and intraspinal grafting of EGF/bFGF-dependent neurospheres derived from embryonic rat spinal cord

    S. Y. Chow;J. Moul;C. A. Tobias;B. T. Himes

Frequent Co-Authors

Alan Tessler
Alan Tessler Drexel University
Marion Murray
Marion Murray Drexel University
Angelo C. Lepore
Angelo C. Lepore Thomas Jefferson University
Pat Levitt
Pat Levitt University of Southern California
Ralph A. Nixon
Ralph A. Nixon Nathan Kline Institute for Psychiatric Research
Armin Blesch
Armin Blesch Indiana University
Mark H. Tuszynski
Mark H. Tuszynski University of California, San Diego
Wolfram Tetzlaff
Wolfram Tetzlaff University of British Columbia
Jacqueline C. Bresnahan
Jacqueline C. Bresnahan University of California, San Francisco
Timothy J Schallert
Timothy J Schallert The University of Texas at Austin

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