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Neuroscience

D-Index
39
Citations
5385
World Ranking
8371
National Ranking
3576

Overview

Angelo C. Lepore is affiliated with Thomas Jefferson University in the United States. Their research primarily spans the fields of Medicine and Neuroscience, with a particular focus on several subfields including Pathology and Forensic Medicine, Cellular and Molecular Neuroscience, Physiology, Endocrine and Autonomic Systems, and Neurology.

The main topics of their research include:

  • Spinal Cord Injury Research
  • Neuroscience of respiration and sleep
  • Pain Mechanisms and Treatments
  • Neurogenesis and neuroplasticity mechanisms
  • Nerve injury and regeneration
  • Neonatal Respiratory Health Research
  • Musculoskeletal pain and rehabilitation

Angelo C. Lepore has published in numerous scientific venues, frequently contributing to:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Experimental Neurology
  • Glia
  • Neurobiology of Disease
  • Cells

Frequent collaborators include:

  • Nicolette M. Heinsinger
  • Megan C. Wright
  • Samantha J. Thomas
  • Eric V. Brown
  • Biswarup Ghosh

Selected recent publications by Angelo C. Lepore include:

  • "Glial restricted precursor cells in central nervous system disorders: Current applications and future perspectives," 2020, Glia
  • "Cervical spinal cord injury-induced neuropathic pain in male mice is associated with a persistent pro-inflammatory macrophage/microglial response in the superficial dorsal horn," 2021, Experimental Neurology
  • "LAR inhibitory peptide promotes recovery of diaphragm function and multiple forms of respiratory neural circuit plasticity after cervical spinal cord injury," 2020, Neurobiology of Disease
  • "Differential Activation of Pain Circuitry Neuron Populations in a Mouse Model of Spinal Cord Injury-Induced Neuropathic Pain," 2022, Journal of Neuroscience
  • "Intestinal neuropod cell GUCY2C regulates visceral pain," 2022, Journal of Clinical Investigation

Best Publications

  • Focal transplantation-based astrocyte replacement is neuroprotective in a model of motor neuron disease.

    Angelo C Lepore;Britta Rauck;Christine Dejea;Andrea C Pardo

  • Presynaptic regulation of astroglial excitatory neurotransmitter transporter GLT1.

    Yongjie Yang;Oguz Gozen;Andrew Watkins;Ileana Lorenzini

  • Astrocytes carrying the superoxide dismutase 1 (SOD1G93A) mutation induce wild-type motor neuron degeneration in vivo

    Sophia T. Papadeas;Sarah E. Kraig;Colin O'Banion;Angelo C. Lepore

  • Transplantation of Neuronal and Glial Restricted Precursors into Contused Spinal Cord Improves Bladder and Motor Functions, Decreases Thermal Hypersensitivity, and Modifies Intraspinal Circuitry

    Takahiko Mitsui;Jed S. Shumsky;Angelo C. Lepore;Marion Murray

  • Lineage-restricted neural precursors survive, migrate, and differentiate following transplantation into the injured adult spinal cord.

    A.C. Lepore;I. Fischer

  • Long-term fate of neural precursor cells following transplantation into developing and adult CNS.

    A.C. Lepore;B. Neuhuber;T.M. Connors;S.S.W. Han

  • Minimally invasive delivery of stem cells for spinal cord injury: advantages of the lumbar puncture technique

    Ajay Bakshi;Corey Hunter;Sharon Swanger;Angelo Lepore

  • Neural precursor cells can be delivered into the injured cervical spinal cord by intrathecal injection at the lumbar cord

    Angelo C. Lepore;Ajay Bakshi;Sharon A. Swanger;Mahendra S. Rao

  • Intraparenchymal spinal cord delivery of adeno-associated virus IGF-1 is protective in the SOD1G93A model of ALS.

    Angelo C. Lepore;Christine Haenggeli;Mehdi Gasmi;Kathie M. Bishop

  • Human Glial-Restricted Progenitor Transplantation into Cervical Spinal Cord of the SOD1G93A Mouse Model of ALS

    Angelo C. Lepore;John O'Donnell;Andrew S. Kim;Timothy Williams

  • Differential fate of multipotent and lineage-restricted neural precursors following transplantation into the adult CNS.

    Angelo C. Lepore;Steven S.W. Han;Carla J. Tyler-Polsz;Jingli Cai

  • Distinct roles for spinophilin and neurabin in dopamine-mediated plasticity.

    P.B. Allen;V. Zachariou;P. Svenningsson;P. Svenningsson;A.C. Lepore

  • Phrenic motor neuron degeneration compromises phrenic axonal circuitry and diaphragm activity in a unilateral cervical contusion model of spinal cord injury.

    Charles Nicaise;Charles Nicaise;Tamara J Hala;David M Frank;Jessica L Parker;Jessica L Parker

  • Inhibiting drug efflux transporters improves efficacy of ALS therapeutics.

    Michael R. Jablonski;Shashirekha S. Markandaiah;Dena Jacob;Ni J. Meng

  • Adult glial precursor proliferation in mutant SOD1G93A mice.

    Tim Magnus;Jessica Carmen;Jessica Deleon;Haipeng Xue

  • Selective ablation of proliferating astrocytes does not affect disease outcome in either acute or chronic models of motor neuron degeneration

    Angelo C. Lepore;Christine Dejea;Jessica Carmen;Britta Rauck

  • MR imaging of lineage-restricted neural precursors following transplantation into the adult spinal cord.

    A.C. Lepore;P. Walczak;M.S. Rao;I. Fischer

  • Transplantation of Human Glial Restricted Progenitors and Derived Astrocytes into a Contusion Model of Spinal Cord Injury

    Ying Jin;Birgit Neuhuber;Anita Singh;Julien Bouyer

  • Transplantation of stem cell-derived astrocytes for the treatment of amyotrophic lateral sclerosis and spinal cord injury

    Charles Nicaise;Dinko Mitrecic;Aditi Falnikar;Angelo C Lepore

  • Long-term fate of neural precursor cells following transplantation into developing and adult CNS (DOI: 10.1016/j.neuroscience.2005.12.043)

    A. C. Lepore;B. Neuhuber;T. M. Connors;S. S W Han

Frequent Co-Authors

Itzhak Fischer
Itzhak Fischer Drexel University
George M. Smith
George M. Smith Temple University
Jeffrey D. Rothstein
Jeffrey D. Rothstein Johns Hopkins University
Jeannie Chin
Jeannie Chin Baylor College of Medicine
Lorraine Iacovitti
Lorraine Iacovitti Thomas Jefferson University
Jian Feng
Jian Feng University at Buffalo, State University of New York
Zhen Yan
Zhen Yan University at Buffalo, State University of New York
Nuno Sousa
Nuno Sousa University of Minho
Paul Greengard
Paul Greengard Rockefeller University
Richard J. Smeyne
Richard J. Smeyne Thomas Jefferson University

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