What is she best known for?
The fields of study she is best known for:
- Gene
- Internal medicine
- Disease
Pamela J. Shaw spends much of her time researching Amyotrophic lateral sclerosis, Pathology, Neuroscience, Motor neuron and Genetics.
Specifically, her work in Amyotrophic lateral sclerosis is concerned with the study of SOD1.
Her research integrates issues of Motor cortex and Neuroglia in her study of Pathology.
Her studies deal with areas such as Excitotoxicity, Oxidative stress, Disease and Mitochondrion as well as Neuroscience.
The study incorporates disciplines such as Calcium-binding protein and Central nervous system in addition to Motor neuron.
Pamela J. Shaw works mostly in the field of Genetics, limiting it down to concerns involving Internal medicine and, occasionally, Physical therapy.
Her most cited work include:
- Frequency of the C9orf72 hexanucleotide repeat expansion in patients with amyotrophic lateral sclerosis and frontotemporal dementia: a cross-sectional study (832 citations)
- Pathological TDP-43 distinguishes sporadic amyotrophic lateral sclerosis from amyotrophic lateral sclerosis with SOD1 mutations (724 citations)
- Effects of non-invasive ventilation on survival and quality of life in patients with amyotrophic lateral sclerosis: a randomised controlled trial. (710 citations)
What are the main themes of her work throughout her whole career to date?
Amyotrophic lateral sclerosis, Pathology, Neuroscience, Motor neuron and Genetics are her primary areas of study.
Pamela J. Shaw has researched Amyotrophic lateral sclerosis in several fields, including C9orf72 and Neurodegeneration.
Pamela J. Shaw interconnects White matter and Hyperintensity in the investigation of issues within Pathology.
Her Neuroscience study incorporates themes from Glutamate receptor and Excitotoxicity.
Pamela J. Shaw focuses mostly in the field of SOD1, narrowing it down to matters related to Cell biology and, in some cases, Neuroprotection.
Her biological study spans a wide range of topics, including Endocrinology, Surgery, Oncology and Cardiology.
She most often published in these fields:
- Amyotrophic lateral sclerosis (48.64%)
- Pathology (20.24%)
- Neuroscience (19.05%)
What were the highlights of her more recent work (between 2018-2021)?
- Amyotrophic lateral sclerosis (48.64%)
- Disease (12.93%)
- Genetics (14.97%)
In recent papers she was focusing on the following fields of study:
Her primary areas of investigation include Amyotrophic lateral sclerosis, Disease, Genetics, Internal medicine and Gene.
Amyotrophic lateral sclerosis is a subfield of Pathology that Pamela J. Shaw explores.
Her Motor neurone disease and Spinocerebellar ataxia study in the realm of Pathology interacts with subjects such as Late stage.
Her work deals with themes such as Clinical trial, MEDLINE, Respiratory capacity, Biomarker and Pediatrics, which intersect with Disease.
Her Internal medicine research incorporates elements of Endocrinology, Oncology and Cardiology.
Her Gene study combines topics from a wide range of disciplines, such as Neuropathology and Bioinformatics.
Between 2018 and 2021, her most popular works were:
- Phase 1–2 Trial of Antisense Oligonucleotide Tofersen for SOD1 ALS (85 citations)
- Exome sequencing in amyotrophic lateral sclerosis implicates a novel gene, DNAJC7 , encoding a heat-shock protein (44 citations)
- Biomarkers in Motor Neuron Disease: A State of the Art Review. (36 citations)
In her most recent research, the most cited papers focused on:
- Gene
- Internal medicine
- Disease
Her scientific interests lie mostly in Amyotrophic lateral sclerosis, C9orf72, Genetics, Disease and Motor neuron.
Pathology and Internal medicine are the subject areas of her Amyotrophic lateral sclerosis study.
Her C9orf72 research includes themes of DNA methylation, Epigenetics, Gene mutation and Motor neurone disease.
Pamela J. Shaw has included themes like Neurodegeneration and Sudden cardiac death in her Genetics study.
Pamela J. Shaw has researched Disease in several fields, including Usual care, MEDLINE, Nursing and Process evaluation.
The various areas that Pamela J. Shaw examines in her Motor neuron study include Denervation, Astrocyte, Neuron, Sonic hedgehog and Cell biology.
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