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69
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2339
National Ranking
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Overview

Karen E. Morrison is affiliated with the University of Southampton in the United Kingdom. The scientist's research work spans several fields within medicine and biochemistry, genetics, and molecular biology, with a primary focus on neurological and genetic disorders.

The main fields of study associated with Karen E. Morrison include:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Their subfields of study cover more specific areas such as:

  • Neurology
  • Genetics
  • Molecular Biology
  • Radiology, Nuclear Medicine and Imaging
  • Physiology

The principal research topics they address involve:

  • Amyotrophic Lateral Sclerosis Research
  • Neurogenetic and Muscular Disorders Research
  • Neurological diseases and metabolism
  • Parkinson's Disease Mechanisms and Treatments
  • Genetic Associations and Epidemiology
  • Genetics and Neurodevelopmental Disorders
  • Boron Compounds in Chemistry

Karen E. Morrison has contributed to multiple recent papers, including:

  • Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology, 2021, Nature Genetics
  • Finding genetically-supported drug targets for Parkinson's disease using Mendelian randomization of the druggable genome, 2021, Nature Communications
  • Transethnic Genome-Wide Association Study Provides Insights in the Genetic Architecture and Heritability of Long QT Syndrome, 2020, Circulation
  • Genome-wide identification of the genetic basis of amyotrophic lateral sclerosis, 2022, Neuron
  • Meta-analysis of genome-wide DNA methylation identifies shared associations across neurodegenerative disorders, 2021, Genome biology

The venues that frequently publish the scientist's work include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • SSRN Electronic Journal
  • Brain
  • Nature Genetics
  • Neurology

Among their frequent co-authors are:

  • Pamela J. Shaw
  • Ammar Al-Chalabi
  • Jan H. Veldink
  • Christopher E. Shaw
  • Alfredo Iacoangeli

Best Publications

  • Frequency of the C9orf72 hexanucleotide repeat expansion in patients with amyotrophic lateral sclerosis and frontotemporal dementia: a cross-sectional study

    Elisa Majounie;Alan E. Renton;Kin Mok;Elise G. P. Dopper;Elise G. P. Dopper

  • EFNS guidelines on the Clinical Management of Amyotrophic Lateral Sclerosis (MALS) : revised report of an EFNS task force

    Peter M. Andersen;Sharon Abrahams;Gian D. Borasio;Mamede de Carvalho

  • VEGF is a modifier of amyotrophic lateral sclerosis in mice and humans and protects motoneurons against ischemic death

    Diether Lambrechts;Erik Storkebaum;Masafumi Morimoto;Jurgen Del-Favero

  • ANG mutations segregate with familial and 'sporadic' amyotrophic lateral sclerosis

    Matthew J Greenway;Peter M Andersen;Carsten Russ;Sean Ennis

  • Genome-wide Analyses Identify KIF5A as a Novel ALS Gene.

    Aude Nicolas;Kevin P. Kenna;Alan E. Renton;Alan E. Renton;Nicola Ticozzi

  • Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis

    Wouter van Rheenen;Aleksey Shatunov;Annelot M. Dekker;Russell L. McLaughlin

  • ALS phenotypes with mutations in CHMP2B (charged multivesicular body protein 2B)

    N. Parkinson;P. G. Ince;M. O. Smith;R. Highley

  • Loss of VPS13C Function in Autosomal-Recessive Parkinsonism Causes Mitochondrial Dysfunction and Increases PINK1/Parkin-Dependent Mitophagy.

    Suzanne Lesage;Valérie Drouet;Elisa Majounie;Vincent Deramecourt

  • Exome-wide rare variant analysis identifies TUBA4A mutations associated with familial ALS.

    B N Smith;N Ticozzi;C Fallini;A S Gkazi

  • Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease

    A. Beilina;I. N. Rudenko;A. Kaganovich;L. Civiero

  • A Two-Stage Meta-Analysis Identifies Several New Loci for Parkinson's Disease

    V. Plagnol;M.A. Nalls;J.M. Bras;D.G. Hernandez;D.G. Hernandez

  • Detection of long repeat expansions from PCR-free whole-genome sequence data.

    Egor Dolzhenko;Joke J.F.A. van Vugt;Richard J. Shaw;Mitchell A. Bekritsky

  • NEK1 variants confer susceptibility to amyotrophic lateral sclerosis

    Kevin P Kenna;Perry T C van Doormaal;Annelot M Dekker;Nicola Ticozzi

  • Mutations in CHMP2B in lower motor neuron predominant amyotrophic lateral sclerosis (ALS).

    Laura E. Cox;Laura Ferraiuolo;Emily F. Goodall;Paul R. Heath

  • The C9ORF72 expansion mutation is a common cause of ALS+/-FTD in Europe and has a single founder.

    Bradley N. Smith;Stephen Newhouse;Aleksey Shatunov;Caroline Vance

  • Chromosome 9p21 in sporadic amyotrophic lateral sclerosis in the UK and seven other countries: a genome-wide association study

    Aleksey Shatunov;Kin Mok;Stephen Newhouse;Michael E Weale

  • Frequency and clinical characteristics of progranulin mutation carriers in the Manchester frontotemporal lobar degeneration cohort: comparison with patients with MAPT and no known mutations

    Stuart M. Pickering-Brown;Sara Rollinson;Daniel Du Plessis;Karen E. Morrison

  • A distinct clinical, neuropsychological and radiological phenotype is associated with progranulin gene mutations in a large UK series

    Jonathan Beck;Jonathan D. Rohrer;Tracy Campbell;Adrian Isaacs

  • Common and rare variant association analyses in Amyotrophic Lateral Sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology

    Wouter van Rheenen;Rick A. A. van der Spek;Mark K. Bakker;Joke J. F. A. van Vugt

  • Genome-Wide Analyses Identify KIF5A as a Novel ALS Gene

    Aude Nicolas;Kevin P. Kenna;Alan E. Renton;Nicola Ticozzi

Frequent Co-Authors

Ammar Al-Chalabi
Ammar Al-Chalabi King's College London
Pamela J. Shaw
Pamela J. Shaw University of Sheffield
Christopher Shaw
Christopher Shaw King's College London
Orla Hardiman
Orla Hardiman Trinity College Dublin
John Landers
John Landers University of Massachusetts Chan Medical School
Jan H. Veldink
Jan H. Veldink Utrecht University
Alexis Brice
Alexis Brice Institut du Cerveau
Leonard H. van den Berg
Leonard H. van den Berg Utrecht University
Adriano Chiò
Adriano Chiò University of Turin

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