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Genetics
UK
2024

D-Index & Metrics

Genetics

D-Index
113
Citations
70582
World Ranking
479
National Ranking
78

Medicine

D-Index
121
Citations
79596
World Ranking
3536
National Ranking
354

Research.com Recognitions

  • 2024 - Research.com Genetics in United Kingdom Leader Award
  • 2023 - Research.com Genetics in United Kingdom Leader Award

Overview

Christopher Shaw is affiliated with King's College London in the United Kingdom and has published extensively in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their research primarily focuses on Neurology, Genetics, and Molecular Biology, with additional work in Physiology and Cellular and Molecular Neuroscience.

Their research topics cover areas such as Amyotrophic Lateral Sclerosis Research, Neurogenetic and Muscular Disorders Research, Neurological diseases and metabolism, Parkinson's Disease Mechanisms and Treatments, Epigenetics and DNA Methylation, RNA Research and Splicing, and Alzheimer's disease research and treatments.

Christopher Shaw has published frequently in several scientific venues. These include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Brain
  • Brain Communications
  • Nature Communications
  • Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration

Several papers authored or co-authored by Christopher Shaw demonstrate the scope of their work. Among these are:

  • "Transethnic Genome-Wide Association Study Provides Insights in the Genetic Architecture and Heritability of Long QT Syndrome" (2020) published in Circulation
  • "Genome-wide identification of the genetic basis of amyotrophic lateral sclerosis" (2022) published in Neuron
  • "Meta-analysis of genome-wide DNA methylation identifies shared associations across neurodegenerative disorders" (2021) published in Genome Biology
  • "Genome-wide study of DNA methylation shows alterations in metabolic, inflammatory, and cholesterol pathways in ALS" (2022) published in Science Translational Medicine
  • "CYLD is a causative gene for frontotemporal dementia - amyotrophic lateral sclerosis" (2020) published in Brain

The scientist collaborates frequently with a group of coauthors, including Ammar Al-Chalabi, Pamela J. Shaw, Jan H. Veldink, Karen Morrison, and Alfredo Iacoangeli. These partnerships reflect a collaborative approach in investigating neurological and genetic conditions associated with neurodegenerative diseases.

Best Publications

  • Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

    Denise Harold;Richard Abraham;Paul Hollingworth;Rebecca Sims

  • TDP-43 Mutations in Familial and Sporadic Amyotrophic Lateral Sclerosis

    Jemeen Sreedharan;Ian P. Blair;Vineeta B. Tripathi;Xun Hu

  • Mutations in FUS, an RNA Processing Protein, Cause Familial Amyotrophic Lateral Sclerosis Type 6

    Caroline Vance;Boris Rogelj;Tibor Hortobágyi;Kurt J. De Vos

  • Erratum: Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease (Nature Genetics (2009) 41 (1088-1093))

    D Harold;R Abraham;P Hollingworth;R Sims

  • Expected performance of the ATLAS experiment - detector, trigger and physics

    G. Aad;E. Abat;B. Abbott;J. Abdallah

  • Expected Performance of the ATLAS Experiment - Detector, Trigger and Physics

    G. Aad;E. Abat;B. Abbott

  • Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease.

    Paul Hollingworth;Denise Harold;Rebecca Sims;Amy Gerrish

  • Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS

    Hong Joo Kim;Nam Chul Kim;Yong Dong Wang;Emily A. Scarborough

  • Charged-particle multiplicities in pp interactions measured with the ATLAS detector at the LHC

    G. Aad;B. Abbott;J. Abdallah;A. A. Abdelalim

  • Characterizing the RNA targets and position-dependent splicing regulation by TDP-43

    James Robert Tollervey;Tomaž Curk;Boris Rogelj;Michael Briese

  • VEGF is a modifier of amyotrophic lateral sclerosis in mice and humans and protects motoneurons against ischemic death

    Diether Lambrechts;Erik Storkebaum;Masafumi Morimoto;Jurgen Del-Favero

  • Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

    Rebecca Sims;Sven J. Van Der Lee;Adam C. Naj;Céline Bellenguez;Céline Bellenguez

  • Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways

    Elizabeth T. Cirulli;Brittany N Lasseigne;Slave Petrovski;Peter C Sapp

  • Evidence of widespread cerebral microglial activation in amyotrophic lateral sclerosis: an [11C](R)-PK11195 positron emission tomography study

    M R Turner;A Cagnin;F E Turkheimer;F E Turkheimer;Christopher Miller

  • Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease.

    Lesley Jones;Peter A. Holmans;Marian L. Hamshere;Denise Harold

  • Genome-wide Analyses Identify KIF5A as a Novel ALS Gene.

    Aude Nicolas;Kevin P. Kenna;Alan E. Renton;Alan E. Renton;Nicola Ticozzi

  • Axonal Transport of TDP-43 mRNA Granules Is Impaired by ALS-Causing Mutations

    Nael H. Alami;Rebecca B. Smith;Monica A. Carrasco;Luis A. Williams

  • ER–mitochondria associations are regulated by the VAPB–PTPIP51 interaction and are disrupted by ALS/FTD-associated TDP-43

    Radu Stoica;Kurt J. De Vos;Kurt J. De Vos;Sébastien Paillusson;Sarah Mueller

  • Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimertextquotesingles disease

    Denise Harold;Richard Abraham;Paul Hollingworth;Rebecca Sims

  • Supporting Online Material for Mutations in FUS, an RNA Processing Protein, Cause Familial Amyotrophic Lateral Sclerosis Type 6

    Caroline Vance;Boris Rogelj;Tibor Hortobágyi;Kurt J. De Vos

Frequent Co-Authors

Ammar Al-Chalabi
Ammar Al-Chalabi King's College London
David W. Halton
David W. Halton Queen's University Belfast
Aaron G. Maule
Aaron G. Maule Queen's University Belfast
Ian Fairweather
Ian Fairweather Queen's University Belfast
P. Nigel Leigh
P. Nigel Leigh Brighton and Sussex Medical School
Pamela J. Shaw
Pamela J. Shaw University of Sheffield
Karen E. Morrison
Karen E. Morrison University of Southampton
Orla Hardiman
Orla Hardiman Trinity College Dublin
John Landers
John Landers University of Massachusetts Chan Medical School
Jan H. Veldink
Jan H. Veldink Utrecht University

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