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Biology and Biochemistry
Hungary
2026

D-Index & Metrics

Biology and Biochemistry

D-Index
70
Citations
21114
World Ranking
6919
National Ranking
6

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in Hungary Leader Award
  • 2025 - Research.com Biology and Biochemistry in Hungary Leader Award
  • 2023 - Research.com Biology and Biochemistry in Hungary Leader Award
  • 2022 - Research.com Biology and Biochemistry in Hungary Leader Award
  • 2005 - Member of Academia Europaea

Overview

Balázs Sarkadi is affiliated with the TTK Research Centre for Natural Sciences in Hungary. Their research spans multiple fields within medicine and biochemistry, genetics, and molecular biology. The scientist has contributed significantly to areas such as drug transport and resistance mechanisms, SARS-CoV-2 and COVID-19 research, RNA interference and gene delivery, trace elements in health, pharmacological effects and toxicity studies, gout, hyperuricemia, uric acid, and hemoglobinopathies and related disorders.

Balázs Sarkadi's recent publication record includes the following papers:

  • Structural and functional diversity calls for a new classification of ABC transporters, 2020, FEBS Letters
  • The ABCG2/BCRP transporter and its variants - from structure to pathology, 2020, FEBS Letters
  • Interactions of Potential Anti-COVID-19 Compounds with Multispecific ABC and OATP Drug Transporters, 2021, Pharmaceutics
  • Interactions of anti-COVID-19 drug candidates with hepatic transporters may cause liver toxicity and affect pharmacokinetics, 2021, Scientific Reports
  • RBD-specific antibody responses after two doses of BBIBP-CorV (Sinopharm, Beijing CNBG) vaccine, 2022, BMC Infectious Diseases

The frequent coauthors who have collaborated extensively with Balázs Sarkadi include Orsolya Mózner, György Várady, Edit Szabó, Ágnes Telbisz, and Anna Kulin.

Several scientific journals have been preferred venues for publication, such as:

  • International Journal of Molecular Sciences
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Zenodo (CERN European Organization for Nuclear Research)
  • Preprints.org
  • FEBS Letters

The scientist has been recognized as a Member of Academia Europaea since 2005.

Best Publications

  • Human Multidrug Resistance ABCB and ABCG Transporters: Participation in a Chemoimmunity Defense System

    Balázs Sarkadi;László Homolya;Gergely Szakács;András Váradi

  • The stem cell marker Bcrp/ABCG2 enhances hypoxic cell survival through interactions with heme.

    Partha Krishnamurthy;Douglas D. Ross;Douglas D. Ross;Takeo Nakanishi;Kim Bailey-Dell

  • Expression of the human multidrug resistance cDNA in insect cells generates a high activity drug-stimulated membrane ATPase.

    Balazs Sarkadi;Elmer M. Price;Richard C. Boucher;Ursula A. Germann

  • The role of ABC transporters in drug absorption, distribution, metabolism, excretion and toxicity (ADME-Tox).

    Gergely Szakács;András Váradi;Csilla Özvegy-Laczka;Balázs Sarkadi

  • Efficiency of gene transfer for restoration of normal airway epithelial function in cystic fibrosis

    Larry G. Johnson;John C. Olsen;Balazs Sarkadi;Karen L. Moore

  • Functional characterization of the human multidrug transporter, ABCG2, expressed in insect cells.

    Csilla Özvegy;Thomas Litman;Gergely Szakács;Zoltán Nagy

  • Functional multidrug resistance protein (MRP1) lacking the N-terminal transmembrane domain.

    Éva Bakos;Raymond Evers;Gergely Szakács;Gábor E. Tusnády

  • High-affinity interaction of tyrosine kinase inhibitors with the ABCG2 multidrug transporter

    Csilla Ozvegy-Laczka;Tamás Hegedus;György Várady;Olga Ujhelly

  • ABCG2 - A transporter for all seasons

    Balázs Sarkadi;Csilla Özvegy-Laczka;Katalin Német;András Váradi

  • Membrane topology distinguishes a subfamily of the ATP-binding cassette (ABC) transporters

    Gábor E Tusnády;Éva Bakos;András Váradi;Balázs Sarkadi

  • The role of multidrug transporters in drug availability, metabolism and toxicity.

    Adrienn Bodó;Éva Bakos;Flóra Szeri;András Váradi

  • Multidrug Transporter ABCG2 Prevents Tumor Cell Death Induced by the Epidermal Growth Factor Receptor Inhibitor Iressa (ZD1839, Gefitinib)

    N. Barry Elkind;Zsófia Szentpétery;Ágota Apáti;Csilla Özvegy-Laczka

  • Loss of ATP-dependent Transport Activity in Pseudoxanthoma Elasticum-associated Mutants of Human ABCC6 (MRP6)

    Attila Iliás;Zsolt Urbán;Thomas L. Seidl;Olivier Le Saux

  • Characterization of drug transport, ATP hydrolysis, and nucleotide trapping by the human ABCG2 multidrug transporter. Modulation of substrate specificity by a point mutation.

    Csilla Özvegy;András Váradi;Balázs Sarkadi

  • Multidrug resistance-associated proteins: Export pumps for conjugates with glutathione, glucuronate or sulfate.

    László Homolya;András Váradi;Balázs Sarkadi

  • Membrane topology and glycosylation of the human multidrug resistance-associated protein.

    Éva Bakos;Tamás Hegedüs;Zsolt Holló;Ervin Welker

  • Single nucleotide polymorphisms modify the transporter activity of ABCG2

    Kuniaki Morisaki;Robert W. Robey;Csilla Özvegy-Laczka;Yasumasa Honjo

  • Interaction of nilotinib, dasatinib and bosutinib with ABCB1 and ABCG2: implications for altered anti-cancer effects and pharmacological properties

    C Hegedűs;C Özvegy-Laczka;Á Apáti;M Magócsi

  • Interaction of tyrosine kinase inhibitors with the human multidrug transporter proteins, MDR1 and MRP1.

    Tamás Hegedűs;László Őrfi;Attila Seprődi;András Váradi

  • and directly interacts with drugs as judged by interference with nucleotide trapping

    Alexander J. Smith;Ardy van Helvoort;Gerrit van Meer;Katalin Szabó

Frequent Co-Authors

András Váradi
András Váradi Hungarian Academy of Sciences
Zsuzsanna Izsvák
Zsuzsanna Izsvák Max Delbrück Center for Molecular Medicine
Zoltán Ivics
Zoltán Ivics Paul Ehrlich Institut
Brian P. Sorrentino
Brian P. Sorrentino St. Jude Children's Research Hospital
Nikolay V. Dokholyan
Nikolay V. Dokholyan Pennsylvania State University
György Kéri
György Kéri Semmelweis University
Susan E. Bates
Susan E. Bates Columbia University
Péter Ferdinandy
Péter Ferdinandy Semmelweis University
Giovanni Migliaccio
Giovanni Migliaccio University of Washington
Michael Dean
Michael Dean National Institutes of Health

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