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Biology and Biochemistry

D-Index
93
Citations
34317
World Ranking
2085
National Ranking
1136

Overview

Zhe-Sheng Chen is affiliated with St. John's University in the United States, focusing on medical and biochemical research. Their research spans multiple subfields including molecular biology, oncology, cancer research, pulmonary and respiratory medicine, and infectious diseases.

The scientist has contributed extensively to the study of drug transport and resistance mechanisms, cancer therapeutics and mechanisms, HIV/AIDS drug development and treatment, RNA modifications and cancer, epigenetics and DNA methylation, nanoparticle-based drug delivery, and nanoplatforms for cancer theranostics.

Frequent coauthors of Zhe-Sheng Chen include Jing-Quan Wang, Zhuo-Xun Wu, Zi-Ning Lei, Qiu-Xu Teng, and Yuqi Yang, indicating active collaboration in their research endeavors.

They have published multiple papers with notable venues being Frontiers in Pharmacology, Drug Resistance Updates, Molecular Cancer, Advanced Science, and Frontiers in Oncology.

Significant recent publications are:

  • Microbiota in health and diseases, 2022, Signal Transduction and Targeted Therapy
  • Antimicrobial peptides for combating drug-resistant bacterial infections, 2023, Drug Resistance Updates
  • Advancements in clinical aspects of targeted therapy and immunotherapy in breast cancer, 2023, Molecular Cancer
  • m6A modification: recent advances, anticancer targeted drug discovery and beyond, 2022, Molecular Cancer
  • Advancements in nanoparticle-based treatment approaches for skin cancer therapy, 2023, Molecular Cancer

Zhe-Sheng Chen is also an author of several books published by Frontiers Media, including Tumor Microenvironment and Cancer Therapy (2023), Novel Biomarkers for Anticancer Therapy (2023), and Role of Gut Microbiota in Diabetes Mellitus and Tumor Immunity (2023).

Best Publications

  • Biosynthesis of nanoparticles by microorganisms and their applications

    Xiangqian Li;Huizhong Xu;Zhe-Sheng Chen;Guofang Chen

  • The development of anticancer ruthenium(II) complexes: from single molecule compounds to nanomaterials

    Leli Zeng;Pranav Gupta;Yanglu Chen;Enju Wang

  • Silver nanoparticles: synthesis, properties, and therapeutic applications.

    Liuya Wei;Jingran Lu;Huizhong Xu;Atish Patel

  • The modulation of ABC transporter-mediated multidrug resistance in cancer: a review of the past decade.

    Rishil J. Kathawala;Pranav Gupta;Charles R. Ashby;Zhe-Sheng Chen

  • Overcoming ABC transporter-mediated multidrug resistance: Molecular mechanisms and novel therapeutic drug strategies

    Wen Li;Han Zhang;Yehuda G. Assaraf;Kun Zhao

  • Autophagy and multidrug resistance in cancer

    Ying-Jie Li;Yu-He Lei;Nan Yao;Chen-Ran Wang

  • Modulating ROS to overcome multidrug resistance in cancer.

    Qingbin Cui;Jing-Quan Wang;Yehuda G. Assaraf;Liang Ren

  • Transport of cyclic nucleotides and estradiol 17-beta-D-glucuronide by multidrug resistance protein 4. Resistance to 6-mercaptopurine and 6-thioguanine.

    Zhe-Sheng Chen;Kun Lee;Gary D. Kruh

  • Copper-transporting P-type adenosine triphosphatase (ATP7B) is associated with cisplatin resistance

    Masaharu Komatsu;Tomoyuki Sumizawa;Masato Mutoh;Zhe-Sheng Chen

  • Lapatinib (Tykerb, GW572016) Reverses Multidrug Resistance in Cancer Cells by Inhibiting the Activity of ATP-Binding Cassette Subfamily B Member 1 and G Member 2

    Chun Ling Dai;Amit K. Tiwari;Chung Pu Wu;Xiao Dong Su

  • Analysis of methotrexate and folate transport by multidrug resistance protein 4 (ABCC4): MRP4 is a component of the methotrexate efflux system.

    Zhe-Sheng Chen;Kun Lee;Susan Walther;Rebecca Blanchard Raftogianis

  • Transport of methotrexate, methotrexate polyglutamates, and 17β-estradiol 17-(β-D-glucuronide) by ABCG2: Effects of acquired mutations at R482 on methotrexate transport

    Zhe Sheng Chen;Robert W. Robey;Martin G. Belinsky;Irina Shchaveleva

  • BCR-ABL tyrosine kinase inhibitors in the treatment of Philadelphia chromosome positive chronic myeloid leukemia: a review.

    Xin An;Amit K. Tiwari;Yibo Sun;Pei Rong Ding;Pei Rong Ding

  • Apatinib (YN968D1) Reverses Multidrug Resistance by Inhibiting the Efflux Function of Multiple ATP-Binding Cassette Transporters

    Yan Jun Mi;Yong Ju Liang;Hong Bing Huang;Hong Yun Zhao

  • Transport of Methotrexate (MTX) and Folates by Multidrug Resistance Protein (MRP) 3 and MRP1 Effect of Polyglutamylation on MTX Transport

    Hao Zeng;Zhe-Sheng Chen;Martin G. Belinsky;Philip A. Rea

  • Erlotinib (Tarceva, OSI-774) Antagonizes ATP-Binding Cassette Subfamily B Member 1 and ATP-Binding Cassette Subfamily G Member 2–Mediated Drug Resistance

    Zhi Shi;Xing Xiang Peng;In Wha Kim;Suneet Shukla

  • Characterization of the Drug Resistance and Transport Properties of Multidrug Resistance Protein 6 (MRP6, ABCC6)

    Martin G. Belinsky;Zhe-Sheng Chen;Irina Shchaveleva;Hao Zeng

  • MRP8, ATP-binding Cassette C11 (ABCC11), Is a Cyclic Nucleotide Efflux Pump and a Resistance Factor for Fluoropyrimidines 2′,3′-Dideoxycytidine and 9′-(2′-Phosphonylmethoxyethyl)adenine *

    Yanping Guo;Elena Kotova;Zhe-Sheng Chen;Kun Lee

  • Multidrug resistance proteins (MRPs/ABCCs) in cancer chemotherapy and genetic diseases

    Zhe‐Sheng Chen;Amit K. Tiwari

  • Multidrug resistance associated proteins in multidrug resistance

    Kamlesh Sodani;Atish Patel;Rishil J. Kathawala;Zhe-Sheng Chen

Frequent Co-Authors

Suresh V. Ambudkar
Suresh V. Ambudkar National Institutes of Health
Tomoyuki Sumizawa
Tomoyuki Sumizawa Kagoshima University
Shin-ichi Akiyama
Shin-ichi Akiyama Kagoshima University
Tatsuhiko Furukawa
Tatsuhiko Furukawa Kagoshima University
Hong-Min Liu
Hong-Min Liu Zhengzhou University
Wen-Cai Ye
Wen-Cai Ye Jinan University
Shunji Aoki
Shunji Aoki Hyogo University of Health Sciences
Jinyi Xu
Jinyi Xu China Pharmaceutical University
Yehuda G. Assaraf
Yehuda G. Assaraf Technion – Israel Institute of Technology
Susan E. Bates
Susan E. Bates Columbia University

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