D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 71 Citations 15,782 263 World Ranking 4225 National Ranking 41

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Cancer

His scientific interests lie mostly in Pharmacology, Multiple drug resistance, Cancer, Biochemistry and Drug. His studies in Pharmacology integrate themes in fields like Cell culture, Abcg2, Efflux, Antifolate and Multidrug resistance-associated protein 2. His study in Antifolate is interdisciplinary in nature, drawing from both Transporter and Dihydrofolate reductase.

The Multiple drug resistance study combines topics in areas such as Cancer cell, Lipid bilayer and Liposome. His work carried out in the field of Cancer brings together such families of science as Precision medicine, Apoptosis, Drug resistance and Intracellular. In his research, ATPase, Peripheral blood mononuclear cell and Carfilzomib is intimately related to P-glycoprotein, which falls under the overarching field of Biochemistry.

His most cited work include:

  • Antifolate resistance mediated by the multidrug resistance proteins MRP1 and MRP2. (400 citations)
  • Molecular basis of bortezomib resistance: proteasome subunit beta5 (PSMB5) gene mutation and overexpression of PSMB5 protein (339 citations)
  • Nanomedicine for targeted cancer therapy: Towards the overcoming of drug resistance (337 citations)

What are the main themes of his work throughout his whole career to date?

His main research concerns Cancer research, Pharmacology, Biochemistry, Antifolate and Multiple drug resistance. He interconnects Cancer, Leukemia, Immunology, Bortezomib and Drug resistance in the investigation of issues within Cancer research. The study incorporates disciplines such as Cell culture, Transporter, Abcg2 and Multidrug resistance-associated protein 2 in addition to Pharmacology.

His Antifolate research incorporates themes from Molecular biology and Dihydrofolate reductase. The concepts of his Molecular biology study are interwoven with issues in Proteasome inhibitor, Mutation, Gene silencing, Gene and Membrane transport protein. His Multiple drug resistance study incorporates themes from Cancer cell and Efflux.

He most often published in these fields:

  • Cancer research (29.92%)
  • Pharmacology (25.00%)
  • Biochemistry (18.44%)

What were the highlights of his more recent work (between 2017-2021)?

  • Cancer research (29.92%)
  • Cancer (17.62%)
  • Drug resistance (16.80%)

In recent papers he was focusing on the following fields of study:

Yehuda G. Assaraf spends much of his time researching Cancer research, Cancer, Drug resistance, Multiple drug resistance and Cancer cell. His Cancer research study combines topics in areas such as Tumor microenvironment, Pemetrexed, Paclitaxel, Lung cancer and Drug. His research integrates issues of Extracellular, Cytoplasm and Homeostasis in his study of Cancer.

His Multiple drug resistance study combines topics from a wide range of disciplines, such as ATP-binding cassette transporter, Efflux, Endoplasmic reticulum, Membrane fluidity and Casein micelles. His Efflux research is included under the broader classification of Biochemistry. His biological study spans a wide range of topics, including Targeted therapy and Computational biology.

Between 2017 and 2021, his most popular works were:

  • Modulating ROS to overcome multidrug resistance in cancer. (123 citations)
  • The multi-factorial nature of clinical multidrug resistance in cancer. (69 citations)
  • Redundant angiogenic signaling and tumor drug resistance. (43 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Cancer

Yehuda G. Assaraf focuses on Cancer research, Drug resistance, Cancer, Multiple drug resistance and Cancer cell. He has included themes like Acute myeloblastic leukemia, Cancer therapy and Lung cancer in his Cancer research study. Yehuda G. Assaraf works mostly in the field of Drug resistance, limiting it down to topics relating to microRNA and, in certain cases, Long non-coding RNA, Anticancer drug and Cancer drugs, as a part of the same area of interest.

His studies deal with areas such as Receptor-mediated endocytosis and A549 cell as well as Cancer. In his research on the topic of Multiple drug resistance, Tariquidar, Mitochondrion, Organelle localization and P-glycoprotein is strongly related with Efflux. His Cancer cell research integrates issues from HeLa, Internalization, Targeted drug delivery and Endocytosis.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Antifolate resistance mediated by the multidrug resistance proteins MRP1 and MRP2.

Jan Hendrik Hooijberg;Henk J. Broxterman;Marcel Kool;Yehuda G. Assaraf.
Cancer Research (1999)

581 Citations

Molecular basis of bortezomib resistance: proteasome subunit beta5 (PSMB5) gene mutation and overexpression of PSMB5 protein

Ruud Oerlemans;Niels E. Franke;Yehuda G. Assaraf;Jacqueline Cloos.
Blood (2008)

494 Citations

Nanomedicine for targeted cancer therapy: Towards the overcoming of drug resistance

Alina Shapira;Yoav D. Livney;Henk J. Broxterman;Yehuda G. Assaraf.
Drug Resistance Updates (2011)

444 Citations

Molecular basis of antifolate resistance.

Yehuda G. Assaraf.
Cancer and Metastasis Reviews (2007)

399 Citations

Antifolates in cancer therapy: structure, activity and mechanisms of drug resistance.

Nitzan Gonen;Yehuda G. Assaraf.
Drug Resistance Updates (2012)

367 Citations

Lysosomal sequestration of sunitinib: a novel mechanism of drug resistance

Kristy J. Gotink;Henk J. Broxterman;Mariette Labots;Richard R. de Haas.
Clinical Cancer Research (2011)

305 Citations

Overcoming ABC transporter-mediated multidrug resistance: Molecular mechanisms and novel therapeutic drug strategies

Wen Li;Han Zhang;Yehuda G. Assaraf;Kun Zhao.
Drug Resistance Updates (2016)

278 Citations

The folate receptor as a rational therapeutic target for personalized cancer treatment

Yehuda G. Assaraf;Christopher P. Leamon;Joseph A. Reddy.
Drug Resistance Updates (2014)

243 Citations

The role of multidrug resistance efflux transporters in antifolate resistance and folate homeostasis.

Yehuda G. Assaraf.
Drug Resistance Updates (2006)

238 Citations

Lysosomes as mediators of drug resistance in cancer.

Benny Zhitomirsky;Yehuda G. Assaraf.
Drug Resistance Updates (2016)

237 Citations

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