Stig Linder

Research.com Recognitions

• 2023 - Research.com Biology and Biochemistry in Sweden Leader Award

Overview

Best Publications

• Cisplatin Induces Endoplasmic Reticulum Stress and Nucleus-independent Apoptotic Signaling

  Aleksandra Mandic;Johan Hansson;Stig Linder;Maria C. Shoshan

  657
  Citations

• Inhibition of proteasome deubiquitinating activity as a new cancer therapy

  Pádraig D'Arcy;Slavica Brnjic;Maria Hägg Olofsson;Mårten Fryknäs

  545
  Citations

• Differentiation between cell death modes using measurements of different soluble forms of extracellular cytokeratin 18.

  Gero Kramer;Hamdiye Erdal;Helena J. M. M. Mertens;Marius Nap

  387
  Citations

• Deubiquitinase inhibition as a cancer therapeutic strategy.

  Padraig D'Arcy;Xin Wang;Stig Linder

  331
  Citations

• A novel small molecule inhibitor of deubiquitylating enzyme USP14 and UCHL5 induces apoptosis in multiple myeloma and overcomes bortezomib resistance.

  Ze Tian;Padraig D’Arcy;Xin Wang;Arghya Ray

  329
  Citations

• Calpain-Mediated Bid Cleavage and Calpain-Independent Bak Modulation: Two Separate Pathways in Cisplatin-Induced Apoptosis

  Aleksandra Mandic;Kristina Viktorsson;Linda Strandberg;Thomas Heiden

  285
  Citations

• Acute apoptosis by cisplatin requires induction of reactive oxygen species but is not associated with damage to nuclear DNA

  Maria Berndtsson;Maria Hägg;Theocharis Panaretakis;Aleksandra Mandic Havelka

  276
  Citations

• Induction of lysosomal membrane permeabilization by compounds that activate p53-independent apoptosis

  Hamdiye Erdal;Maria Berndtsson;Juan Castro;Ulf Brunk

  274
  Citations

• Acidic extracellular pH neutralizes the autophagy-inhibiting activity of chloroquine: Implications for cancer therapies

  Paola Pellegrini;Angela Strambi;Chiara Zipoli;Maria Hägg-Olofsson

  260
  Citations

• Induction of mitochondrial dysfunction as a strategy for targeting tumour cells in metabolically compromised microenvironments

  Xiaonan Zhang;Mårten Fryknäs;Emma Hernlund;Walid Fayad

  253
  Citations

• Irreversible inhibition of cytosolic thioredoxin reductase 1 as a mechanistic basis for anticancer therapy.

  William C. Stafford;Xiaoxiao Peng;Maria Hägg Olofsson;Xiaonan Zhang

  238
  Citations

• Screening of Germline Mutations in the CDKN2A and CDKN2B Genes in Swedish Families With Hereditary Cutaneous Melanoma

  Platz A;Hansson J;Månsson-Brahme E;Lagerlof B

  223
  Citations

• Cancer proteomics: From identification of novel markers to creation of artifical learning models for tumor classification

  Ayodele A. Alaiya;Bo Franzén;Gert Auer;Stig Linder

  209
  Citations

• Autophagy Is a Protective Mechanism for Human Melanoma Cells under Acidic Stress

  Maria Lucia Marino;Paola Pellegrini;Giuseppe Di Lernia;Mojgan Djavaheri-Mergny

  194
  Citations

• A novel high-through-put assay for screening of pro-apoptotic drugs.

  Maria Hägg;Kenneth Bivén;Takayuki Ueno;Lars Rydlander

  188
  Citations

• Processing of pulmonary surfactant protein B by napsin and cathepsin H

  Takayuki Ueno;Stig Linder;Cheng-Lun Na;Ward R. Rice

  183
  Citations

• Determining tumor apoptosis and necrosis in patient serum using cytokeratin 18 as a biomarker.

  Stig Linder;Aleksandra Mandic Havelka;Takayuki Ueno;Maria C. Shoshan

  181
  Citations

• Cytokeratin-18 Is a Useful Serum Biomarker for Early Determination of Response of Breast Carcinomas to Chemotherapy

  Maria Hägg Olofsson;Takayuki Ueno;Takayuki Ueno;Yang Pan;Ren Xu

  177
  Citations

• The proteasome deubiquitinase inhibitor VLX1570 shows selectivity for ubiquitin-specific protease-14 and induces apoptosis of multiple myeloma cells

  Xin Wang;Magdalena Mazurkiewicz;Ellin Kristina Hillert;Maria Hägg Olofsson

  160
  Citations

• Proteasome deubiquitinases as novel targets for cancer therapy

  Pádraig D’Arcy;Stig Linder

  156
  Citations