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Angelo De Milito

Angelo De Milito

D-Index & Metrics

Biology and Biochemistry

D-Index
48
Citations
40245
World Ranking
18164
National Ranking
287

Overview

Angelo De Milito is affiliated with the Karolinska Institute in Sweden. Their research spans several interconnected fields, primarily focusing on immunology and microbiology, as well as biochemistry, genetics, and molecular biology.

Their main research subfields include immunology, molecular biology, epidemiology, oncology, and pulmonary and respiratory medicine. De Milito's work concentrates on topics such as immune cells in cancer, interferon and immune responses, immune cell function and interaction, autophagy in disease and therapy, ubiquitin and proteasome pathways, cancer immunotherapy and biomarkers, and mitochondrial function and pathology.

De Milito has co-authored scientific papers with frequent collaborators including Martin Andersson, Caterina Vianello, Veronica Cocetta, Daniela Catanzaro, and Flavio Rizzolio.

Their publications appear in a variety of scientific journals, with multiple works published in "Cell Death and Disease." Other venues include "Science Advances," "Autophagy," "Molecular Oncology," and "Cancer Research."

Notable recent papers by De Milito include the following:

  • Inhibition of Vps34 reprograms cold into hot inflamed tumors and improves anti-PD-1/PD-L1 immunotherapy, 2020, Science Advances
  • Cisplatin resistance can be curtailed by blunting Bnip3-mediated mitochondrial autophagy, 2022, Cell Death and Disease
  • Lighting up the fire in cold tumors to improve cancer immunotherapy by blocking the activity of the autophagy-related protein PIK3C3/VPS34, 2020, Autophagy
  • Combining VPS34 inhibitors with STING agonists enhances type I interferon signaling and anti-tumor efficacy, 2024, Molecular Oncology
  • Abstract 2116: VPS34 inhibitor SB02024 activates cGAS-STING signaling and sensitizes tumors to STING agonist, 2022, Cancer Research

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Microenvironmental pH Is a Key Factor for Exosome Traffic in Tumor Cells

    Isabella Parolini;Cristina Federici;Carla Raggi;Luana Lugini

  • High Levels of Exosomes Expressing CD63 and Caveolin-1 in Plasma of Melanoma Patients

    Mariantonia Logozzi;Angelo De Milito;Luana Lugini;Martina Borghi

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Modulation of microenvironment acidity reverses anergy in human and murine tumor-infiltrating T lymphocytes.

    Arianna Calcinotto;Paola Filipazzi;Matteo Grioni;Manuela Iero

  • Effect of Proton Pump Inhibitor Pretreatment on Resistance of Solid Tumors to Cytotoxic Drugs

    Francesca Luciani;Massimo Spada;Angelo De Milito;Agnese Molinari

  • Mechanisms of hypergammaglobulinemia and impaired antigen-specific humoral immunity in HIV-1 infection.

    Angelo De Milito;Anna Nilsson;Kehmia Titanji;Rigmor Thorstensson

  • Loss of memory B cells impairs maintenance of long-term serologic memory during HIV-1 infection.

    Kehmia Titanji;Angelo De Milito;Alberto Cagigi;Rigmor Thorstensson

  • Proton Pump Inhibitors Induce Apoptosis of Human B-Cell Tumors through a Caspase-Independent Mechanism Involving Reactive Oxygen Species

    Angelo De Milito;Elisabetta Iessi;Mariantonia Logozzi;Francesco Lozupone

  • Tumor acidity, chemoresistance and proton pump inhibitors.

    Angelo De Milito;Stefano Fais

  • Targeting vacuolar H+-ATPases as a new strategy against cancer.

    Stefano Fais;Angelo De Milito;Haiyan You;Wenxin Qin

  • pH-dependent antitumor activity of proton pump inhibitors against human melanoma is mediated by inhibition of tumor acidity.

    Angelo De Milito;Rossella Canese;Maria Lucia Marino;Martina Borghi

  • Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Acidic extracellular pH neutralizes the autophagy-inhibiting activity of chloroquine: Implications for cancer therapies

    Paola Pellegrini;Angela Strambi;Chiara Zipoli;Maria Hägg-Olofsson

  • Induction of mitochondrial dysfunction as a strategy for targeting tumour cells in metabolically compromised microenvironments

    Xiaonan Zhang;Mårten Fryknäs;Emma Hernlund;Walid Fayad

  • B lymphocyte dysfunctions in HIV infection.

    Angelo De Milito

  • Primary HIV-1 infection sets the stage for important B lymphocyte dysfunctions.

    Kehmia Titanji;Francesca Chiodi;Rino Bellocco;Danika Schepis

  • Proton channels and exchangers in cancer

    Enrico Pierluigi Spugnini;Pierre Sonveaux;Christian Stock;Mario Perez-Sayans

Frequent Co-Authors

Stefano Fais
Stefano Fais Istituto Superiore di Sanità
Francesca Chiodi
Francesca Chiodi Karolinska Institute
Stig Linder
Stig Linder Linköping University
Maurizio Zazzi
Maurizio Zazzi University of Siena
Sergio Lavandero
Sergio Lavandero University of Chile
Evelina Gatti
Evelina Gatti Aix-Marseille University
Paola Matarrese
Paola Matarrese Istituto Superiore di Sanità
Boris Zhivotovsky
Boris Zhivotovsky Karolinska Institute
Licia Rivoltini
Licia Rivoltini Fondazione IRCCS Istituto Nazionale dei Tumori
Beth Levine
Beth Levine The University of Texas Southwestern Medical Center

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