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Des R. Richardson

Des R. Richardson

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Biology and Biochemistry
Australia
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
116
Citations
61129
World Ranking
742
National Ranking
17

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Australia Leader Award

Overview

Des R. Richardson is affiliated with Griffith University in Australia and has contributed extensively to the fields of biochemistry, genetics, molecular biology, and medicine. Their research spans multiple subfields including molecular biology, materials chemistry, oncology, cell biology, and physiology.

The scientist's work covers key topics such as mechanisms of cancer metastasis, crystallization and solubility studies, X-ray diffraction in crystallography, metal complexes synthesis and properties, autophagy in disease and therapy, cancer mechanisms and therapy, and the intersections of cancer, lipids, and metabolism.

Frequent coauthors collaborating with Des R. Richardson include Mahendiran Dharmasivam, Mahan Gholam Azad, Büşra Kaya, Tharushi P. Wijesinghe, and Paul V. Bernhardt.

Des R. Richardson has published in a range of venues, with a notable number of publications appearing in The Cambridge Structural Database, Pharmacological Research, Pharmacological Reviews, Biochimica et Biophysica Acta (BBA) - General Subjects, and the Journal of Medicinal Chemistry.

Selected recent papers authored by Des R. Richardson include:

  • Ferritinophagy and ferroptosis in the management of metabolic diseases, 2021, Trends in Endocrinology and Metabolism
  • CD63 is regulated by iron via the IRE-IRP system and is important for ferritin secretion by extracellular vesicles, 2021, Blood
  • Changes in ferrous iron and glutathione promote ferroptosis and frailty in aging Caenorhabditis elegans, 2020, eLife
  • Parkinson's disease: Alterations in iron and redox biology as a key to unlock therapeutic strategies, 2021, Redox Biology
  • The Role of Extracellular Proteases in Tumor Progression and the Development of Innovative Metal Ion Chelators That Inhibit Their Activity, 2020, International Journal of Molecular Sciences

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • The Evolution of Iron Chelators for the Treatment of Iron Overload Disease and Cancer

    Danuta S. Kalinowski;Des R. Richardson

  • The molecular mechanisms of the metabolism and transport of iron in normal and neoplastic cells.

    Des R Richardson;Prem Ponka

  • Function and regulation of transferrin and ferritin

    P Ponka;C Beaumont;D R Richardson

  • Lipid-Based Drug Delivery Systems in Cancer Therapy: What Is Available and What Is Yet to Come.

    Phatsapong Yingchoncharoen;Danuta S. Kalinowski;Des R. Richardson

  • Unraveling the mysteries of serum albumin—more than just a serum protein

    Angelica M. Merlot;Danuta S. Kalinowski;Des R. Richardson

  • A class of iron chelators with a wide spectrum of potent antitumor activity that overcomes resistance to chemotherapeutics

    Megan Whitnall;Jonathan Howard;Prem Ponka;Des R. Richardson

  • The role of iron in cell cycle progression and the proliferation of neoplastic cells.

    Nghia T V Le;Des R Richardson

  • Iron uptake and metabolism in the new millennium.

    Louise L. Dunn;Yohan Suryo Rahmanto;Des R. Richardson

  • Mitochondrial iron trafficking and the integration of iron metabolism between the mitochondrion and cytosol.

    Des R. Richardson;Darius J. R. Lane;Erika M. Becker;Michael L.-H. Huang

  • Thiosemicarbazones from the old to new: iron chelators that are more than just ribonucleotide reductase inhibitors

    Yu Yu;Danuta S. Kalinowski;Zaklina Kovacevic;Aritee R. Siafakas

  • Novel di-2-pyridyl-derived iron chelators with marked and selective antitumor activity: in vitro and in vivo assessment

    Jun Yuan;David B. Lovejoy;Des R. Richardson

  • Dipyridyl thiosemicarbazone chelators with potent and selective antitumor activity form iron complexes with redox activity.

    Des R. Richardson;Philip C. Sharpe;David B. Lovejoy;Dakshita Senaratne

  • The potential of iron chelators of the pyridoxal isonicotinoyl hydrazone class as effective antiproliferative agents.

    D R Richardson;E H Tran;E H Tran;P Ponka;P Ponka

  • Cellular iron uptake, trafficking and metabolism: Key molecules and mechanisms and their roles in disease.

    D.J.R. Lane;A.M. Merlot;M.L.-H. Huang;D.-H. Bae

  • Iron trafficking in the mitochondrion: novel pathways revealed by disease.

    Ian Napier;Prem Ponka;Des R. Richardson

  • Cancer cell iron metabolism and the development of potent iron chelators as anti-tumour agents

    D.R. Richardson;D.S. Kalinowski;S. Lau;P.J. Jansson

  • Design, Synthesis, and Characterization of Novel Iron Chelators: Structure−Activity Relationships of the 2-Benzoylpyridine Thiosemicarbazone Series and Their 3-Nitrobenzoyl Analogues as Potent Antitumor Agents

    Danuta S Kalinowski;Yu Yu;Philip C Sharpe;Mohammad Islam

Frequent Co-Authors

Danuta S. Kalinowski
Danuta S. Kalinowski University of Sydney
Paul V. Bernhardt
Paul V. Bernhardt University of Queensland
Prem Ponka
Prem Ponka McGill University
Clare L. Hawkins
Clare L. Hawkins University of Copenhagen
Shinya Toyokuni
Shinya Toyokuni Nagoya University
Victor R. Gordeuk
Victor R. Gordeuk University of Illinois at Chicago
Josef Jampilek
Josef Jampilek University of Silesia
Evelina Gatti
Evelina Gatti Aix-Marseille University
Sergio Lavandero
Sergio Lavandero University of Chile
Terence P. Speed
Terence P. Speed Walter and Eliza Hall Institute of Medical Research

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