His primary areas of study are Biochemistry, Ferritin, Transferrin receptor, Metabolism and Transferrin. His work on Biochemistry is being expanded to include thematically relevant topics such as Cell biology. His Ferritin research is multidisciplinary, incorporating elements of Internal ribosome entry site, Ferroportin, Proteasome, Heme and Protein biosynthesis.
His Transferrin receptor research integrates issues from Amino acid, Oxygenase, Ubiquitin, DMT1 and Cysteine. The study incorporates disciplines such as Malignant transformation, Cancer research, Oxidative stress and Siderosis in addition to Metabolism. His research integrates issues of Metalloprotein and Endocytosis in his study of Cytosol.
His scientific interests lie mostly in Biochemistry, Transferrin receptor, Ferritin, Cell biology and Hepcidin. Transferrin receptor is a subfield of Transferrin that he studies. His study in Heme extends to Ferritin with its themes.
The various areas that Kostas Pantopoulos examines in his Cell biology study include Oxidative stress, Regulation of gene expression and Mutant. His Hepcidin study integrates concerns from other disciplines, such as Hemochromatosis and Endocrinology. His study in Cytosol is interdisciplinary in nature, drawing from both Metalloprotein and Endocytosis.
Kostas Pantopoulos mostly deals with Hepcidin, Internal medicine, Endocrinology, Ferroportin and Hemochromatosis. His Hepcidin research is multidisciplinary, incorporating perspectives in Transferrin receptor, Hormone, Serum iron and Iron deficiency. His Transferrin receptor study results in a more complete grasp of Transferrin.
His research integrates issues of Receptor, HAMP, Ferritin and Cell type in his study of Transferrin. His research investigates the link between Ferroportin and topics such as Cell biology that cross with problems in Lipid peroxidation and Bone marrow. His Hemochromatosis research incorporates themes from Biochemistry and Hemojuvelin.
Kostas Pantopoulos mostly deals with Hepcidin, Ferroportin, Hemochromatosis, Anemia and Hereditary hemochromatosis. His work carried out in the field of Hepcidin brings together such families of science as Transferrin receptor and Endocrinology. His Transferrin receptor research entails a greater understanding of Transferrin.
His Transferrin study combines topics in areas such as Receptor, HAMP, Ferritin and Cell type. His study looks at the relationship between Anemia and fields such as Immunology, as well as how they intersect with chemical problems. His study in Hereditary hemochromatosis is interdisciplinary in nature, drawing from both Anemia of chronic disease and Ineffective erythropoiesis.
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Iron metabolism and toxicity.
G. Papanikolaou;K. Pantopoulos;K. Pantopoulos.
Toxicology and Applied Pharmacology (2005)
Regulation of cellular iron metabolism
Jian Wang;Kostas Pantopoulos;Kostas Pantopoulos;Kostas Pantopoulos.
Biochemical Journal (2011)
Iron metabolism and the IRE/IRP regulatory system: an update
Annals of the New York Academy of Sciences (2004)
Mechanisms of mammalian iron homeostasis
Kostas Pantopoulos;Suheel Kumar Porwal;Alan Michael Tartakoff;L. Devireddy.
Translational regulation via iron-responsive elements by the nitric oxide/NO-synthase pathway
G Weiss;B Goossen;W Doppler;D Fuchs.
The EMBO Journal (1993)
Regulation of iron transport and the role of transferrin.
Konstantinos Gkouvatsos;George Papanikolaou;Kostas Pantopoulos.
Biochimica et Biophysica Acta (2012)
Rapid responses to oxidative stress mediated by iron regulatory protein.
K. Pantopoulos;M.W. Hentze.
The EMBO Journal (1995)
Oxidative stress and iron homeostasis: mechanistic and health aspects.
Dimitrios Galaris;Kostas Pantopoulos.
Critical Reviews in Clinical Laboratory Sciences (2008)
Alcohol metabolism-mediated oxidative stress down-regulates hepcidin transcription and leads to increased duodenal iron transporter expression.
Duygu Dee Harrison-Findik;Denise Schafer;Elizabeth Klein;Nikolai A. Timchenko.
Journal of Biological Chemistry (2006)
Nitric oxide signaling to iron-regulatory protein: direct control of ferritin mRNA translation and transferrin receptor mRNA stability in transfected fibroblasts.
Kostas Pantopoulos;Matthias W. Hentze.
Proceedings of the National Academy of Sciences of the United States of America (1995)
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