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Paolo Arosio

Paolo Arosio

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Biology and Biochemistry
Switzerland
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
105
Citations
39774
World Ranking
1199
National Ranking
26

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Switzerland Leader Award

Overview

Paolo Arosio is affiliated with ETH Zurich in Switzerland and has a significant research presence in the field of Biochemistry, Genetics and Molecular Biology, with a particular focus on Molecular Biology, Biomedical Engineering, Radiology, Nuclear Medicine and Imaging, Physiology, and Materials Chemistry.

Their primary research topics cover a variety of areas including:

  • Protein purification and stability
  • RNA research and splicing
  • Protein structure and dynamics
  • Viral infectious diseases and gene expression in insects
  • Monoclonal and polyclonal antibodies research
  • Alzheimer's disease research and treatments
  • Extracellular vesicles in disease

Paolo Arosio has published extensively in several venues, with frequent contributions found in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Analytical Chemistry
  • Nature Communications
  • Molecular Pharmaceutics
  • Small

Some recent papers authored by or involving Paolo Arosio include:

  • "Dynamics of oligomer populations formed during the aggregation of Alzheimer's Aβ42 peptide" (2020) published in Nature Chemistry
  • "Machine Learning for Biologics: Opportunities for Protein Engineering, Developability, and Formulation" (2021) published in Trends in Pharmacological Sciences
  • "The interface of condensates of the hnRNPA1 low-complexity domain promotes formation of amyloid fibrils" (2023) published in Nature Chemistry
  • "Nanoalgosomes: Introducing extracellular vesicles produced by microalgae" (2021) published in Journal of Extracellular Vesicles
  • "Dynamic arrest and aging of biomolecular condensates are modulated by low-complexity domains, RNA and biochemical activity" (2022) published in Nature Communications

Frequent collaborators in Paolo Arosio's research are:

  • Umberto Capasso Palmiero
  • Andreas M. Küffner
  • Lenka Faltova
  • Tuomas P. J. Knowles
  • Carolina Paganini

Best Publications

  • The ferritins: molecular properties, iron storage function and cellular regulation☆

    Pauline M. Harrison;Paolo Arosio

  • Ferritins: a family of molecules for iron storage, antioxidation and more.

    Paolo Arosio;Rosaria Ingrassia;Patrizia Cavadini

  • Solving the structure of human H ferritin by genetically engineering intermolecular crystal contacts.

    D. M. Lawson;P. J. Artymiuk;S. J. Yewdall;J. M. A. Smith

  • Self-assembling peptide and protein amyloids: from structure to tailored function in nanotechnology

    Gang Wei;Zhiqiang Su;Nicholas P. Reynolds;Paolo Arosio

  • On the lag phase in amyloid fibril formation

    Paolo Arosio;Tuomas Pertti Knowles;Sara Linse

  • Molecular mechanisms of protein aggregation from global fitting of kinetic models

    Georg Meisl;Julius B Kirkegaard;Paolo Arosio;Thomas C T Michaels

  • Ferritin, iron homeostasis, and oxidative damage.

    Paolo Arosio;Sonia Levi

  • On ferritin heterogeneity. Further evidence for heteropolymers.

    P. Arosio;T.G. Adelman;J.W. Drysdale

  • The role of iron and copper molecules in the neuronal vulnerability of locus coeruleus and substantia nigra during aging

    Luigi Zecca;Antonella Stroppolo;Alberto Gatti;Davide Tampellini

  • Mechanism of ferritin iron uptake: activity of the H-chain and deletion mapping of the ferro-oxidase site. A study of iron uptake and ferro-oxidase activity of human liver, recombinant H-chain ferritins, and of two H-chain deletion mutants.

    S Levi;A Luzzago;G Cesareni;A Cozzi

  • A human mitochondrial ferritin encoded by an intronless gene.

    Sonia Levi;Barbara Corsi;Marta Bosisio;Rosangela Invernizzi

  • A molecular chaperone breaks the catalytic cycle that generates toxic Aβ oligomers

    Samuel I A Cohen;Paolo Arosio;Jenny Presto;Firoz Roshan Kurudenkandy

  • Structure, function, and evolution of ferritins

    S. C. Andrews;Paolo Arosio;W. Bottke;J. F. Briat

  • A quantitative analysis of isoferritins in select regions of aged, parkinsonian, and Alzheimer's diseased brains.

    James R. Connor;Brian S. Snyder;Paolo Arosio;David A. Loeffler

  • Identification of the ferroxidase centre in ferritin

    David M. Lawson;Amyra Treffry;Peter J. Artymiuk;Pauline M. Harrison

  • Evidence of H- and L-chains have co-operative roles in the iron-uptake mechanism of human ferritin.

    S Levi;S J Yewdall;P M Harrison;P Santambrogio

  • Cytosolic and mitochondrial ferritins in the regulation of cellular iron homeostasis and oxidative damage

    Paolo Arosio;Sonia Levi

  • Iron Homeostasis in Health and Disease.

    Raffaella Gozzelino;Paolo Arosio

  • Early embryonic lethality of H ferritin gene deletion in mice.

    Chrystophe Ferreira;Danièle Bucchini;Marie Elise Martin;Sonia Levi

  • Ferritin, cellular iron storage and regulation

    Paolo Arosio;Leonardo Elia;Maura Poli

Frequent Co-Authors

Sonia Levi
Sonia Levi Vita-Salute San Raffaele University
Tuomas P. J. Knowles
Tuomas P. J. Knowles University of Cambridge
Christopher M. Dobson
Christopher M. Dobson University of Cambridge
Michele Vendruscolo
Michele Vendruscolo University of Cambridge
Sara Linse
Sara Linse Lund University
Alberto Albertini
Alberto Albertini Catholic University of the Sacred Heart
Claudio Sangregorio
Claudio Sangregorio National Research Council (CNR)
Mario Cazzola
Mario Cazzola University of Pavia
Massimo Morbidelli
Massimo Morbidelli Polytechnic University of Milan
N. Dennis Chasteen
N. Dennis Chasteen University of New Hampshire

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