World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
105
Citations
34873
World Ranking
1213
National Ranking
717

Research.com Recognitions

  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Tracey A. Rouault is a researcher affiliated with the National Institutes of Health in the United States. Their work primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a focus on various related subfields including Molecular Biology, Renewable Energy, Sustainability and the Environment, Hematology, Infectious Diseases, and Genetics.

The main scientific topics addressed in Tracey A. Rouault's research include:

  • Metalloenzymes and iron-sulfur proteins
  • Iron Metabolism and Disorders
  • Trace Elements in Health
  • Folate and B Vitamins Research
  • Neurological diseases and metabolism
  • Hemoglobinopathies and Related Disorders
  • Cancer, Hypoxia, and Metabolism

Several recent publications showcase their research focus and contributions. Selected papers include:

  • "Nitric oxide orchestrates metabolic rewiring in M1 macrophages by targeting aconitase 2 and pyruvate dehydrogenase" (2020), published in Nature Communications
  • "Outlining the Complex Pathway of Mammalian Fe-S Cluster Biogenesis" (2020), published in Trends in Biochemical Sciences
  • "Fe-S cofactors in the SARS-CoV-2 RNA-dependent RNA polymerase are potential antiviral targets" (2021), published in Science
  • "Mitochondrial DNA alterations underlie an irreversible shift to aerobic glycolysis in fumarate hydratase-deficient renal cancer" (2021), published in Science Signaling
  • "Mammalian iron-sulfur cluster biogenesis: Recent insights into the roles of frataxin, acyl carrier protein and ATPase-mediated transfer to recipient proteins" (2020), published in Current Opinion in Chemical Biology

Frequent co-authors working with Tracey A. Rouault include:

  • Nunziata Maio
  • W. Marston Linehan
  • Manik C. Ghosh
  • Sandra Donkervoort
  • J. Martin Bollinger

Their work has appeared in multiple scientific venues, with consistent publications in:

  • Nature Communications
  • HAL (Le Centre pour la Communication Scientifique Directe)
  • Neuromuscular Disorders
  • Proceedings of the National Academy of Sciences
  • International Journal of Molecular Sciences

Tracey A. Rouault has been recognized as a Member of the Association of American Physicians.

Best Publications

  • Regulating the fate of mRNA: The control of cellular iron metabolism

    Richard D. Klausner;Tracey A. Rouault;Joe B. Harford

  • The role of iron regulatory proteins in mammalian iron homeostasis and disease.

    Tracey A Rouault

  • Iron-responsive elements: regulatory RNA sequences that control mRNA levels and translation

    JL Casey;MW Hentze;DM Koeller;SW Caughman

  • A role of SMAD4 in iron metabolism through the positive regulation of hepcidin expression

    Rui Hong Wang;Cuiling Li;Xiaoling Xu;Yin Zheng

  • Identification of the iron-responsive element for the translational regulation of human ferritin mRNA

    MW Hentze;SW Caughman;TA Rouault;JG Barriocanal

  • Targeted deletion of the gene encoding iron regulatory protein-2 causes misregulation of iron metabolism and neurodegenerative disease in mice.

    Timothy LaVaute;Sophia Smith;Sharon Cooperman;Kazuhiro Iwai

  • Iron metabolism in the CNS: implications for neurodegenerative diseases

    Tracey A. Rouault

  • Serum ferritin is derived primarily from macrophages through a nonclassical secretory pathway.

    Lyora A. Cohen;Lucia Gutierrez;Avital Weiss;Yael Leichtmann-Bardoogo

  • Iron–sulphur cluster biogenesis and mitochondrial iron homeostasis

    Tracey A. Rouault;Wing-Hang Tong

  • Genetic ablations of iron regulatory proteins 1 and 2 reveal why iron regulatory protein 2 dominates iron homeostasis

    Esther G Meyron‐Holtz;Manik C Ghosh;Kazuhiro Iwai;Timothy LaVaute

  • Oxidation-reduction and the molecular mechanism of a regulatory RNA-protein interaction.

    Matthias W. Hentze;Tracey A. Rouault;Joe B. Harford;Richard D. Klausner

  • Iron-sulfur cluster biogenesis and human disease.

    Tracey A. Rouault;Wing Hang Tong

  • Binding of a cytosolic protein to the iron-responsive element of human ferritin messenger RNA.

    TA Rouault;MW Hentze;SW Caughman;JB Harford

  • Cellular regulation of the iron-responsive element binding protein: disassembly of the cubane iron-sulfur cluster results in high-affinity RNA binding.

    David J. Haile;Tracey A. Rouault;Joe B. Harford;Mary Claire Kennedy

  • Sedimentation equilibrium analysis of protein interactions with global implicit mass conservation constraints and systematic noise decomposition.

    Jennifer Vistica;Julie Dam;Andrea Balbo;Emine Yikilmaz

  • Functions of mitochondrial ISCU and cytosolic ISCU in mammalian iron-sulfur cluster biogenesis and iron homeostasis

    Wing-Hang Tong;Tracey A. Rouault

  • Iron-dependent regulation of the divalent metal ion transporter

    Hiromi Gunshin;Hiromi Gunshin;Charles R. Allerson;Maria Polycarpou-Schwarz;Andreas Rofts

  • Iron-dependent oxidation, ubiquitination, and degradation of iron regulatory protein 2: Implications for degradation of oxidized proteins

    Kazuhiro Iwai;Steven K. Drake;Nancy B. Wehr;Allan M. Weissman

  • Structural relationship between an iron-regulated RNA-binding protein (IRE-BP) and aconitase: functional implications.

    Tracey A. Rouault;C.David Stout;Stamatina Kaptain;Joe B. Harford

  • Brain iron metabolism.

    Tracey A. Rouault;Sharon Cooperman

Frequent Co-Authors

Joe B. Harford
Joe B. Harford National Institutes of Health
Victor R. Gordeuk
Victor R. Gordeuk University of Illinois at Chicago
Caroline C. Philpott
Caroline C. Philpott National Institutes of Health
W. Marston Linehan
W. Marston Linehan National Institutes of Health
Kazuhiro Iwai
Kazuhiro Iwai Kyoto University
Rodney L. Levine
Rodney L. Levine National Institutes of Health
Matthias W. Hentze
Matthias W. Hentze European Molecular Biology Laboratory
Teresa W.-M. Fan
Teresa W.-M. Fan University of Kentucky
Michael Eckhaus
Michael Eckhaus National Institutes of Health

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Studying Biology or Biochemistry in the USA opens the door to various career paths, including roles in healthcare data and medical administration. Many students pursue online degrees in health information management, benefiting from some of the most affordable online health information management degree programs. These flexible programs prepare graduates for growing fields such as medical coding and health data analysis.

Medical coding is a promising career option, with certified professionals enjoying competitive compensation. To compare earning potential, review the differences in ccs vs cpc salary information. Additionally, understanding the certified medical coder salary can help evaluators make informed career decisions.

Before committing, consider the main question: is medical coding a good job? Exploring real-world pros and cons will help you determine if this pathway aligns with your interests and long-term goals. Overall, pairing a foundational science degree with a health information management credential can provide excellent opportunities for career advancement in both clinical and non-clinical settings.

Best Scientists Citing Tracey A. Rouault

Trending Scientists

Recently Published Articles