Joe B. Harford

Overview

Best Publications

• Regulating the fate of mRNA: The control of cellular iron metabolism

  Richard D. Klausner;Tracey A. Rouault;Joe B. Harford

  1559
  Citations

• Iron-responsive elements: regulatory RNA sequences that control mRNA levels and translation

  JL Casey;MW Hentze;DM Koeller;SW Caughman

  914
  Citations

• Binding of apotransferrin to K562 cells: explanation of the transferrin cycle

  R D Klausner;G Ashwell;J van Renswoude;J B Harford

  805
  Citations

• Identification of the iron-responsive element for the translational regulation of human ferritin mRNA

  MW Hentze;SW Caughman;TA Rouault;JG Barriocanal

  687
  Citations

• Receptor-mediated endocytosis of transferrin and the uptake of fe in K562 cells: identification of a nonlysosomal acidic compartment

  J van Renswoude;K R Bridges;J B Harford;R D Klausner

  662
  Citations

• Antigen activation of murine T cells induces tyrosine phosphorylation of a polypeptide associated with the T cell antigen receptor

  Lawrence E. Samelson;Maitray D. Patel;Allan M. Weissman;Joe B. Harford

  513
  Citations

• Oxidation-reduction and the molecular mechanism of a regulatory RNA-protein interaction.

  Matthias W. Hentze;Tracey A. Rouault;Joe B. Harford;Richard D. Klausner

  451
  Citations

• Iron regulation of transferrin receptor mRNA levels requires iron-responsive elements and a rapid turnover determinant in the 3' untranslated region of the mRNA.

  J.L. Casey;D.M. Koeller;V.C. Ramin;R.D. Klausner

  449
  Citations

• Binding of a cytosolic protein to the iron-responsive element of human ferritin messenger RNA.

  TA Rouault;MW Hentze;SW Caughman;JB Harford

  440
  Citations

• Identification of the components of the murine T cell antigen receptor complex

  Lawrence E. Samelson;Joe B. Harford;Richard D. Klausner

  439
  Citations

• Evidence that the pathway of transferrin receptor mRNA degradation involves an endonucleolytic cleavage within the 3' UTR and does not involve poly(A) tail shortening.

  Roberta Binder;Jill A. Horowitz;James P. Basilion;David M. Koeller

  433
  Citations

• cis-trans models for post-transcriptional gene regulation.

  Richard D. Klausner;Joe B. Harford

  411
  Citations

• Cellular regulation of the iron-responsive element binding protein: disassembly of the cubane iron-sulfur cluster results in high-affinity RNA binding.

  David J. Haile;Tracey A. Rouault;Joe B. Harford;Mary Claire Kennedy

  408
  Citations

• Optimisation of breast cancer management in low-resource and middle-resource countries: executive summary of the Breast Health Global Initiative consensus, 2010

  Benjamin O Anderson;Eduardo Cazap;Nagi S El Saghir;Cheng-Har Yip

  386
  Citations

• Structural relationship between an iron-regulated RNA-binding protein (IRE-BP) and aconitase: functional implications.

  Tracey A. Rouault;C.David Stout;Stamatina Kaptain;Joe B. Harford

  370
  Citations

• Reciprocal control of RNA-binding and aconitase activity in the regulation of the iron-responsive element binding protein: role of the iron-sulfur cluster.

  David J. Haile;Tracey A. Rouault;Careen K. Tang;Jean Chin

  334
  Citations

• A cis-acting element is necessary and sufficient for translational regulation of human ferritin expression in response to iron.

  M W Hentze;T A Rouault;S W Caughman;A Dancis

  329
  Citations

• Challenges and opportunities in cancer control in Africa: a perspective from the African Organisation for Research and Training in Cancer

  Imran O Morhason-Bello;Folakemi Odedina;Timothy R Rebbeck;Joe Harford

  325
  Citations

• A cytosolic protein binds to structural elements within the iron regulatory region of the transferrin receptor mRNA

  David M. Koeller;John L. Casey;Matthias W. Hentze;Elizabeth M. Gerhardt

  300
  Citations

• A regulated RNA binding protein also possesses aconitase activity.

  Stamatina Kaptain;William E. Downey;Careen Tang;Caroline Philpott

  273
  Citations