What is he best known for?
The fields of study he is best known for:
Allan M. Weissman mainly investigates Cell biology, Biochemistry, Ubiquitin, Ubiquitin ligase and Ubiquitin-conjugating enzyme.
The Cell biology study combines topics in areas such as T cell and Lateral inhibition.
His work in the fields of Biochemistry, such as Transfection, COS cells and Plant hormone, overlaps with other areas such as Baculoviral IAP repeat-containing protein 3 and Lateral root.
His studies in Ubiquitin integrate themes in fields like Thymocyte, Endoplasmic reticulum, Auxin and Proteasome.
As a part of the same scientific study, Allan M. Weissman usually deals with the Ubiquitin ligase, concentrating on Apoptosis and frequently concerns with Mitochondrion and Proteolysis.
His Ubiquitin-conjugating enzyme study also includes fields such as
- Protein structure most often made with reference to Ubiquitin-Protein Ligases,
- F-box protein most often made with reference to RING finger domain.
His most cited work include:
- RING finger proteins: mediators of ubiquitin ligase activity. (1090 citations)
- RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination (1005 citations)
- Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuli. (907 citations)
What are the main themes of his work throughout his whole career to date?
His scientific interests lie mostly in Ubiquitin, Cell biology, Biochemistry, Ubiquitin ligase and Molecular biology.
His primary area of study in Ubiquitin is in the field of Ubiquitin-conjugating enzyme.
His Cell biology research is multidisciplinary, incorporating perspectives in Receptor and Transmembrane protein.
His Biochemistry study combines topics in areas such as Cell culture and Biophysics.
His work on Ubiquitin-Protein Ligases as part of general Ubiquitin ligase study is frequently linked to Proto-Oncogene Proteins c-mdm2, therefore connecting diverse disciplines of science.
His studies deal with areas such as Tyrosine phosphorylation, CD8, Gene and T-cell receptor as well as Molecular biology.
He most often published in these fields:
- Ubiquitin (47.73%)
- Cell biology (43.94%)
- Biochemistry (43.18%)
What were the highlights of his more recent work (between 2012-2020)?
- Ubiquitin (47.73%)
- Cell biology (43.94%)
- Ubiquitin ligase (37.88%)
In recent papers he was focusing on the following fields of study:
His primary scientific interests are in Ubiquitin, Cell biology, Ubiquitin ligase, Biochemistry and Ubiquitin-conjugating enzyme.
His Ubiquitin study integrates concerns from other disciplines, such as Saccharomyces cerevisiae, Protein degradation and Proteasome.
His study in the field of Endoplasmic reticulum, Mitochondrion and Structural biology is also linked to topics like Quality.
His Ubiquitin ligase research includes elements of Molecular biology and Actin.
His research integrates issues of Protein structure, Plasma protein binding and Allosteric regulation in his study of Ubiquitin-conjugating enzyme.
He has researched Protein structure in several fields, including Ring finger and Ubiquitin-Protein Ligases.
Between 2012 and 2020, his most popular works were:
- RING-type E3 ligases: master manipulators of E2 ubiquitin-conjugating enzymes and ubiquitination. (326 citations)
- Allosteric regulation of E2:E3 interactions promote a processive ubiquitination machine. (66 citations)
- A structurally unique E2-binding domain activates ubiquitination by the ERAD E2, Ubc7p, through multiple mechanisms. (56 citations)
In his most recent research, the most cited papers focused on:
Allan M. Weissman spends much of his time researching Protein structure, Cell biology, Ubiquitin-conjugating enzyme, Ubiquitin and Ubiquitin ligase.
His study in Protein structure is interdisciplinary in nature, drawing from both Ring finger, Protein degradation, Function, Endoplasmic reticulum and Endoplasmic-reticulum-associated protein degradation.
His Ring finger research incorporates elements of Structural biology, Ubiquitin-Protein Ligases, Allosteric regulation and RING finger domain.
His Cell biology research includes themes of Binding domain and Biochemistry.
His Ubiquitin ligase research incorporates themes from Amino acid, Deubiquitinating enzyme, Protease and Microbiology.
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