World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
76
Citations
28482
World Ranking
4956
National Ranking
2380

Overview

Allan M. Weissman is affiliated with the National Institutes of Health in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Within these areas, their work focuses on several subfields, including Molecular Biology, Cell Biology, Oncology, Hematology, and Immunology and Allergy.

The scientist has contributed extensively to topics such as Endoplasmic Reticulum Stress and Disease, Ubiquitin and proteasome pathways, Peptidase Inhibition and Analysis, RNA modifications and cancer, Cell Adhesion Molecules Research, Melanoma and MAPK Pathways, and Genomics and Chromatin Dynamics.

Allan M. Weissman's recent publications include:

  • Melanoblast transcriptome analysis reveals pathways promoting melanoma metastasis, 2020, Nature Communications
  • Protein Engineering in the Ubiquitin System: Tools for Discovery and Beyond, 2020, Pharmacological Reviews
  • A protein quality control pathway at the mitochondrial outer membrane, 2020, eLife
  • Structural basis for DNA damage-induced phosphoregulation of MDM2 RING domain, 2020, Nature Communications
  • A structurally conserved site in AUP1 binds the E2 enzyme UBE2G2 and is essential for ER-associated degradation, 2021, PLoS Biology

Their frequent co-authors include:

  • Yien Che Tsai
  • Jadranka Lončarek
  • Stephen M. Hewitt
  • Meredith B. Metzger
  • Jessica L. Scales

Allan M. Weissman has published multiple times in well-known scientific venues, such as:

  • Nature Communications
  • Journal of Biological Chemistry
  • Pharmacological Reviews
  • eLife
  • PLoS Biology

Best Publications

  • RING finger proteins: mediators of ubiquitin ligase activity.

    Claudio A.P Joazeiro;Allan M Weissman

  • RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination

    Kevin L. Lorick;Jane P. Jensen;Shengyun Fang;Albert M. Ong

  • Mdm2 Is a RING Finger-dependent Ubiquitin Protein Ligase for Itself and p53

    Shengyun Fang;Jane P. Jensen;Robert L. Ludwig;Karen H. Vousden

  • Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuli.

    Yili Yang;Shengyun Fang;Jane P. Jensen;Allan M. Weissman

  • Serine Phosphorylation-regulated Ubiquitination and Degradation of β-Catenin *

    Keith Orford;Caroline Crockett;Jane P. Jensen;Allan M. Weissman

  • Mind Bomb Is a Ubiquitin Ligase that Is Essential for Efficient Activation of Notch Signaling by Delta

    Motoyuki Itoh;Cheol-Hee Kim;Gregory Palardy;Takaya Oda

  • Ubiquitin and the control of protein fate in the secretory and endocytic pathways.

    Juan S. Bonifacino;Allan M. Weissman

  • HECT and RING finger families of E3 ubiquitin ligases at a glance

    Meredith B. Metzger;Ventzislava A. Hristova;Allan M. Weissman

  • RING-type E3 ligases: master manipulators of E2 ubiquitin-conjugating enzymes and ubiquitination.

    Meredith B. Metzger;Jonathan N. Pruneda;Rachel E. Klevit;Allan M. Weissman

  • SINAT5 promotes ubiquitin-related degradation of NAC1 to attenuate auxin signals

    Qi Xie;Hui-Shan Guo;Geza Dallman;Shengyun Fang

  • Inhibitors of ubiquitin-activating enzyme (E1), a new class of potential cancer therapeutics.

    Yili Yang;Jirouta Kitagaki;Ren-Ming Dai;Yien Che Tsai

  • Antigen activation of murine T cells induces tyrosine phosphorylation of a polypeptide associated with the T cell antigen receptor

    Lawrence E. Samelson;Maitray D. Patel;Allan M. Weissman;Joe B. Harford

  • The tumor autocrine motility factor receptor, gp78, is a ubiquitin protein ligase implicated in degradation from the endoplasmic reticulum

    Shengyun Fang;Marco Ferrone;Cuihong Yang;Jane P. Jensen

  • Failure to synthesize the T Cell CD3-ζ chain: Structure and function of a partial T cell receptor complex

    Jeffrey J. Sussman;Juan S. Bonifacino;Jennifer Lippincott-Schwartz;Allan M. Weissman

  • Small molecule inhibitors of HDM2 ubiquitin ligase activity stabilize and activate p53 in cells

    Yili Yang;Robert L. Ludwig;Jane P. Jensen;Shervon A. Pierre

  • Stress-induced phosphorylation and proteasomal degradation of mitofusin 2 facilitates mitochondrial fragmentation and apoptosis.

    Guillaume P. Leboucher;Yien Che Tsai;Mei Yang;Kristin C. Shaw

  • A field guide to ubiquitylation.

    S Fang;A M Weissman

  • Iron-dependent oxidation, ubiquitination, and degradation of iron regulatory protein 2: Implications for degradation of oxidized proteins

    Kazuhiro Iwai;Steven K. Drake;Nancy B. Wehr;Allan M. Weissman

  • Molecular cloning of the zeta chain of the T cell antigen receptor

    Allan M. Weissman;Michal Baniyash;Damon Hou;Lawrence E. Samelson

  • The predator becomes the prey: regulating the ubiquitin system by ubiquitylation and degradation

    Allan M. Weissman;Nitzan Shabek;Aaron Ciechanover

Frequent Co-Authors

Juan S. Bonifacino
Juan S. Bonifacino National Institutes of Health
Shengyun Fang
Shengyun Fang University of Maryland, Baltimore
Jonathan D. Ashwell
Jonathan D. Ashwell National Institutes of Health
Lawrence E. Samelson
Lawrence E. Samelson National Institutes of Health
Karen H. Vousden
Karen H. Vousden The Francis Crick Institute
Xinhua Ji
Xinhua Ji National Institutes of Health
Joe B. Harford
Joe B. Harford National Institutes of Health
Barry R. O'Keefe
Barry R. O'Keefe National Institutes of Health
John A. Beutler
John A. Beutler National Institutes of Health

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Best Scientists Citing Allan M. Weissman

Trending Scientists

Recently Published Articles