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Immunology
USA
2026

D-Index & Metrics

Immunology

D-Index
140
Citations
65888
World Ranking
164
National Ranking
109

Research.com Recognitions

  • 2026 - Research.com Immunology in United States Leader Award

Overview

Arthur Weiss is affiliated with the University of California, San Francisco in the United States. Their research primarily focuses on immunology, with significant contributions to molecular biology, oncology, genetics, and physiology within the broader fields of immunology and microbiology as well as medicine.

Their work covers a range of main research topics including:

  • Immune Cell Function and Interaction
  • T-cell and B-cell Immunology
  • CAR-T cell therapy research
  • Chronic Lymphocytic Leukemia Research
  • Ubiquitin and proteasome pathways
  • Immunotherapy and Immune Responses
  • Pancreatic function and diabetes

Arthur Weiss has published extensively in several scientific venues. Frequent publication sites include:

  • The Journal of Immunology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Immunology
  • Proceedings of the National Academy of Sciences
  • Science Signaling

Frequent collaborators reflect Weiss's research network and include Wan-Lin Lo, Byron B. Au-Yeung, Theresa A. Kadlecek, Yuan-Li Tsai, and Jay T. Groves.

Notable recent publications that illustrate the focus and scope of their research include:

  • "How the T cell signaling network processes information to discriminate between self and agonist ligands," 2020, Proceedings of the National Academy of Sciences
  • "Unique roles of co-receptor-bound LCK in helper and cytotoxic T cells," 2022, Nature Immunology
  • "ZAP70, too little, too much can lead to autoimmunity*," 2021, Immunological Reviews
  • "A single-amino acid substitution in the adaptor LAT accelerates TCR proofreading kinetics and alters T-cell selection, maintenance and function," 2023, Nature Immunology
  • "Adapting T Cell Receptor Ligand Discrimination Capability via LAT," 2021, Frontiers in Immunology

Best Publications

  • Signal transduction by lymphocyte antigen receptors

    Arthur Weiss;Dan R. Littman

  • ZAP-70: A 70 kd protein-tyrosine kinase that associates with the TCR ζ chain

    Andrew C. Chan;Makio Iwashima;Christoph W. Turck;Arthur Weiss

  • Genetic evidence for the involvement of the lck tyrosine kinase in signal transduction through the T cell antigen receptor.

    David B. Straus;Arthur Weiss

  • ZAP-70 Compared with Immunoglobulin Heavy-Chain Gene Mutation Status as a Predictor of Disease Progression in Chronic Lymphocytic Leukemia

    Laura Z. Rassenti;Lang Huynh;Tracy L. Toy;Liguang Chen

  • CD45: A Critical Regulator of Signaling Thresholds in Immune Cells

    Michelle L Hermiston;Zheng Xu;Arthur Weiss

  • Induction of NF-κB by the Akt/PKB kinase

    Lawrence P. Kane;Virginia Smith Shapiro;David Stokoe;Arthur Weiss

  • The cytoplasmic domain of the T cell receptor ζ chain is sufficient to couple to receptor-associated signal transduction pathways

    Bryan A. Irving;Arthur Weiss

  • Sequential interactions of the TCR with two distinct cytoplasmic tyrosine kinases

    M. Iwashima;B. A. Irving;N. S. C. Van Oers;A. C. Chan;A. C. Chan

  • CD28 Costimulation: From Mechanism to Therapy

    Jonathan H. Esensten;Ynes A. Helou;Gaurav Chopra;Arthur Weiss

  • Activation of the innate immune receptor Dectin-1 upon formation of a /`phagocytic synapse/'

    Helen S. Goodridge;Christopher N. Reyes;Courtney A. Becker;Tamiko R. Katsumoto

  • Function of the Src-family kinases, Lck and Fyn, in T-cell development and activation.

    Emil H Palacios;Arthur Weiss

  • Regulation of interleukin-2 gene enhancer activity by the T cell accessory molecule CD28

    James D. Fraser;Bryan A. Irving;Gerald R. Crabtree;Arthur Weiss

  • The Role of the T3/Antigen Receptor Complex in T-Cell Activation

    Arthur Weiss;John Imboden;Kenneth Hardy;Bernhard Manger

  • The role of T3 surface molecules in the activation of human T cells: a two-stimulus requirement for IL 2 production reflects events occurring at a pre-translational level.

    A Weiss;R L Wiskocil;J D Stobo

  • Jurkat T cells and development of the T-cell receptor signalling paradigm

    Robert T. Abraham;Arthur Weiss

  • T cell antigen receptor signal transduction: A tale of tails and cytoplasmic protein-tyrosine kinases

    Arthur Weiss

  • Expression of ZAP-70 is associated with increased B-cell receptor signaling in chronic lymphocytic leukemia.

    Liguang Chen;George Widhopf;George Widhopf;George Widhopf;Lang Huynh;Lang Huynh;Lang Huynh;Laura Rassenti;Laura Rassenti;Laura Rassenti

  • The role of protein tyrosine kinases and protein tyrosine phosphatases in T cell antigen receptor signal transduction.

    Andrew C. Chan;Dev M. Desai;Arthur Weiss

  • Signal transduction by the TCR for antigen.

    Lawrence P Kane;Joseph Lin;Arthur Weiss

  • Requirement for the coexpression of T3 and the T cell antigen receptor on a malignant human T cell line.

    Arthur Weiss;John D. Stobo

Frequent Co-Authors

John Kuriyan
John Kuriyan Vanderbilt University
John B. Imboden
John B. Imboden University of California, San Francisco
Mark A. Goldsmith
Mark A. Goldsmith Revolution Medicines
Kevan M. Shokat
Kevan M. Shokat University of California, San Francisco
Lewis L. Lanier
Lewis L. Lanier University of California, San Francisco
Lawrence P. Kane
Lawrence P. Kane University of Pittsburgh
Frank W. Fitch
Frank W. Fitch University of Chicago
Gary A. Koretzky
Gary A. Koretzky Cornell University
Dan R. Littman
Dan R. Littman New York University

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