H-Index & Metrics Best Publications

H-Index & Metrics

Discipline name H-index Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 125 Citations 69,791 391 World Ranking 217 National Ranking 12

Research.com Recognitions

Awards & Achievements

2009 - Fellow of the American Association for the Advancement of Science (AAAS)

Member of the European Molecular Biology Organization (EMBO)

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Immune system
  • T cell

The scientist’s investigation covers issues in Cell biology, T cell, Immunological synapse, T-cell receptor and Cell adhesion molecule. Michael L. Dustin has included themes like Immunological synapse formation, Immunology, Cytoskeleton and Antigen-presenting cell in his Cell biology study. His study in T cell is interdisciplinary in nature, drawing from both Acquired immune system, Cytotoxic T cell, Dendritic cell and Cellular differentiation.

Michael L. Dustin interconnects Immunological Synapses and Signal transduction in the investigation of issues within Immunological synapse. His T-cell receptor research is multidisciplinary, incorporating elements of Calcium signaling, Protein kinase A and Actin. His study on Cell adhesion molecule also encompasses disciplines like

  • Cell adhesion, which have a strong connection to Intercellular Adhesion Molecule-1,
  • Neural cell adhesion molecule that intertwine with fields like Intercellular adhesion molecule and Lymphocyte homing receptor.

His most cited work include:

  • The Immunological Synapse: A Molecular Machine Controlling T Cell Activation (2682 citations)
  • ATP mediates rapid microglial response to local brain injury in vivo (2485 citations)
  • Induction by IL 1 and interferon-gamma: tissue distribution, biochemistry, and function of a natural adherence molecule (ICAM-1). (2278 citations)

What are the main themes of his work throughout his whole career to date?

Michael L. Dustin spends much of his time researching Cell biology, T cell, Immunological synapse, T-cell receptor and Immunology. The Cell biology study combines topics in areas such as Cytotoxic T cell, Antigen-presenting cell, Immune system, Immunological Synapses and Cell adhesion. His Cell adhesion research includes themes of Intercellular Adhesion Molecule-1, Cell adhesion molecule and Integrin.

Michael L. Dustin works mostly in the field of Cell adhesion molecule, limiting it down to topics relating to Inflammation and, in certain cases, Antibody, as a part of the same area of interest. His research integrates issues of Receptor and CD8, Antigen in his study of T cell. He focuses mostly in the field of Immunological synapse, narrowing it down to topics relating to Actin and, in certain cases, Cytoskeleton.

He most often published in these fields:

  • Cell biology (64.83%)
  • T cell (34.25%)
  • Immunological synapse (33.18%)

What were the highlights of his more recent work (between 2017-2021)?

  • Cell biology (64.83%)
  • T cell (34.25%)
  • Immunological synapse (33.18%)

In recent papers he was focusing on the following fields of study:

Cell biology, T cell, Immunological synapse, Immune system and T-cell receptor are his primary areas of study. His work carried out in the field of Cell biology brings together such families of science as Receptor, Cell, Immunological Synapses and CD8. His work deals with themes such as Cancer research, Cell growth, Priming, Signal transduction and CD3, which intersect with T cell.

His Immunological synapse research incorporates elements of Dendritic cell, CD28, Chemokine receptor, Actin and Neuroscience. His Immune system study combines topics in areas such as Cytotoxic T cell and Antigen. Michael L. Dustin combines subjects such as CD40, Ligand, Biophysics, Stimulation and Major histocompatibility complex with his study of T-cell receptor.

Between 2017 and 2021, his most popular works were:

  • Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition) (345 citations)
  • Full control of ligand positioning reveals spatial thresholds for T cell receptor triggering. (49 citations)
  • Full control of ligand positioning reveals spatial thresholds for T cell receptor triggering. (49 citations)

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

The Immunological Synapse: A Molecular Machine Controlling T Cell Activation

Arash Grakoui;Shannon K. Bromley;Cenk Sumen;Mark M. Davis.
Science (1999)

3715 Citations

Induction by IL 1 and interferon-gamma: tissue distribution, biochemistry, and function of a natural adherence molecule (ICAM-1).

Michael L. Dustin;Robert Rothlein;Atul K. Bhan;Charles A. Dinarello.
Journal of Immunology (1986)

3115 Citations

ATP mediates rapid microglial response to local brain injury in vivo

Dimitrios Davalos;Jaime Grutzendler;Jaime Grutzendler;Guang Yang;Jiyun V Kim.
Nature Neuroscience (2005)

2990 Citations

T-cell receptor cross-linking transiently stimulates adhesiveness through LFA-1

Michael L. Dustin;Michael L. Dustin;Timothy A. Springer;Timothy A. Springer.
Nature (1989)

1973 Citations

A HUMAN INTERCELLULAR ADHESION MOLECULE (ICAM-1) DISTINCT FROM LFA-1

Robert Rothlein;Michael L. Dustin;Steven D. Marlin;Timothy A. Springer.
Journal of Immunology (1986)

1822 Citations

The lymphocyte function-associated LFA-1, CD2, and LFA-3 molecules: cell adhesion receptors of the immune system.

Timothy A. Springer;Michael L. Dustin;Takashi K. Kishimoto;Steven D. Marlin.
Annual Review of Immunology (1987)

1484 Citations

Lymphocyte Function-associated Antigen-1 (LFA-1) Interaction with Intercellular Adhesion Molecule-1 (ICAM-1) is One of At Least Three Mechanisms for Lymphocyte Adhesion to Cultured Endothelial Cells

Michael L. Dustin;Timothy A. Springer.
Journal of Cell Biology (1988)

1417 Citations

The immunological synapse.

S K Bromley;W R Burack;K G Johnson;K Somersalo.
Annual Review of Immunology (2001)

1147 Citations

Primary structure of ICAM-1 demonstrates interaction between members of the immunoglobulin and integrin supergene families

Donald E. Staunton;Steven D. Marlin;Christian Stratowa;Michael L. Dustin.
Cell (1988)

1129 Citations

Functional cloning of ICAM-2, a cell adhesion ligand for LFA-1 homologous to ICAM-1.

Donald E. Staunton;Michael L. Dustin;Timothy A. Springer.
Nature (1989)

1082 Citations

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