World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
144
Citations
73315
World Ranking
229
National Ranking
158

Research.com Recognitions

  • 2012 - Albert Lasker Award for Basic Medical Research, Lasker Foundation

Overview

Michael P. Sheetz was affiliated with The University of Texas Medical Branch at Galveston in the United States. Their research contributions extended across multiple areas within biochemistry, genetics, molecular biology, and medicine. Their work was documented in a range of publication venues and involved collaboration with several frequent co-authors.

The main fields of study covered by Sheetz included biochemistry, genetics and molecular biology with a total of 78 publications, followed by medicine with 45 publications. Subfields that featured prominently in their work were cell biology (50 publications), biomedical engineering (20), physiology (20), molecular biology (17), and immunology and allergy (8).

They addressed various research topics, including cellular mechanics and interactions, erythrocyte function and pathophysiology, 3D printing in biomedical research, cell adhesion molecules research, microtubule and mitosis dynamics, Hippo pathway signaling and YAP/TAZ, as well as ultrasound and hyperthermia applications. These topics reflected the breadth of their scientific inquiry and methodological approaches.

Frequent co-authors working alongside Michael P. Sheetz were:

  • Mingxi Yao
  • Felix Margadant
  • Ajay Tijore
  • Anushya Hariharan
  • Sanjay Kumar Kureel

Sheetz's publications were often featured in the following venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Frontiers in Cell and Developmental Biology
  • Proceedings of the National Academy of Sciences
  • Biophysical Journal
  • Journal of Cell Science

Recent selected papers include:

  • "Cell response to substrate rigidity is regulated by active and passive cytoskeletal stress," 2020, Proceedings of the National Academy of Sciences
  • "Force- and cell state-dependent recruitment of Piezo1 drives focal adhesion dynamics and calcium entry," 2022, Science Advances
  • "Rapid recruitment of p53 to DNA damage sites directs DNA repair choice and integrity," 2022, Proceedings of the National Academy of Sciences
  • "Selective killing of transformed cells by mechanical stretch," 2021, Biomaterials
  • "Enhanced tumor cell killing by ultrasound after microtubule depolymerization," 2021, Bioengineering & Translational Medicine

The scientist was recognized with the Albert Lasker Award for Basic Medical Research from the Lasker Foundation in 2012, a notable accolade in the biomedical research community.

Best Publications

  • Local force and geometry sensing regulate cell functions.

    Viola Vogel;Michael Sheetz

  • Identification of a novel force-generating protein, kinesin, involved in microtubule-based motility

    Ronald D. Vale;Ronald D. Vale;Ronald D. Vale;Thomas S. Reese;Michael P. Sheetz;Michael P. Sheetz

  • Biological Membranes as Bilayer Couples. A Molecular Mechanism of Drug-Erythrocyte Interactions

    Michael P. Sheetz;S. J. Singer

  • Stretching Single Talin Rod Molecules Activates Vinculin Binding

    Armando del Rio;Raul Perez-Jimenez;Ruchuan Liu;Pere Roca-Cusachs

  • Extracellular Matrix Rigidity Causes Strengthening of Integrin–Cytoskeleton Linkages

    Daniel Choquet;Dan P Felsenfeld;Michael P Sheetz

  • Single particle tracking. Analysis of diffusion and flow in two-dimensional systems.

    H. Qian;Michael Sheetz;E. L. Elson

  • The relationship between force and focal complex development.

    Catherine G. Galbraith;Kenneth M. Yamada;Michael P. Sheetz;Michael P. Sheetz

  • Force Sensing by Mechanical Extension of the Src Family Kinase Substrate p130Cas

    Yasuhiro Sawada;Masako Tamada;Benjamin J. Dubin-Thaler;Oksana Cherniavskaya

  • Pilus retraction powers bacterial twitching motility.

    Alexey J. Merz;Alexey J. Merz;Magdalene So;Michael P. Sheetz;Michael P. Sheetz

  • Tracking kinesin-driven movements with nanometre-scale precision

    Jeff Gelles;Bruce J. Schnapp;Michael P. Sheetz

  • Phosphatidylinositol 4,5-Bisphosphate Functions as a Second Messenger that Regulates Cytoskeleton–Plasma Membrane Adhesion

    Drazen Raucher;Thomas Stauffer;Wen Chen;Kang Shen

  • Appreciating force and shape — the rise of mechanotransduction in cell biology

    Thomas Iskratsch;Haguy Wolfenson;Michael P. Sheetz

  • Periodic Lamellipodial Contractions Correlate with Rearward Actin Waves

    Grégory Giannone;Benjamin J. Dubin-Thaler;Hans Günther Döbereiner;Nelly Kieffer

  • Dynactin, a conserved, ubiquitously expressed component of an activator of vesicle motility mediated by cytoplasmic dynein.

    Steven R. Gill;Trina A. Schroer;Illya Szilak;Eric R. Steuer

  • Cell Spreading and Lamellipodial Extension Rate Is Regulated by Membrane Tension

    Drazen Raucher;Michael P. Sheetz

  • Localization of cytoplasmic dynein to mitotic spindles and kinetochores

    E. R. Steuer;L. Wordeman;T. A. Schroer;Michael Sheetz

  • Cell control by membrane-cytoskeleton adhesion.

    Michael P. Sheetz

  • Lamellipodial Actin Mechanically Links Myosin Activity with Adhesion-Site Formation

    Grégory Giannone;Benjamin J. Dubin-Thaler;Olivier Rossier;Yunfei Cai

  • Movement of myosin-coated fluorescent beads on actin cables in vitro.

    Michael P. Sheetz;James A. Spudich

  • Force of single kinesin molecules measured with optical tweezers

    Scot C. Kuo;Michael P. Sheetz

Frequent Co-Authors

James Hone
James Hone Columbia University
Jie Yan
Jie Yan National University of Singapore
Alexander D. Bershadsky
Alexander D. Bershadsky National University of Singapore
Michael L. Dustin
Michael L. Dustin University of Oxford
Ronald D. Vale
Ronald D. Vale University of California, San Francisco
Trina A. Schroer
Trina A. Schroer Johns Hopkins University
Virginia W. Cornish
Virginia W. Cornish Columbia University
Hanry Yu
Hanry Yu National University of Singapore
Benoit Ladoux
Benoit Ladoux Université Paris Cité
Jianwu Dai
Jianwu Dai Chinese Academy of Sciences

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