2012 - Albert Lasker Award for Basic Medical Research, Lasker Foundation
Cell biology, Cytoskeleton, Biophysics, Integrin and Membrane are his primary areas of study. Cell biology is a component of his Actin, Motility, Extracellular matrix, Focal adhesion and Mechanotransduction studies. His studies deal with areas such as Cell migration, Tension and Membrane lipids as well as Cytoskeleton.
His Biophysics research is multidisciplinary, relying on both Kinesin, Microtubule, Biochemistry and Pilin. His Integrin research incorporates themes from Adhesion, Extracellular, Fibronectin, Vinculin binding and Cell adhesion molecule. His Membrane study combines topics in areas such as Cell cortex and Endocytosis.
Michael P. Sheetz mainly investigates Cell biology, Biophysics, Cytoskeleton, Actin and Integrin. He combines topics linked to Actin cytoskeleton with his work on Cell biology. The Biophysics study combines topics in areas such as Adhesion, Magnetic tweezers, Nanotechnology, Biochemistry and Anatomy.
The concepts of his Cytoskeleton study are interwoven with issues in Membrane and Cell membrane. Microfilament is closely connected to Myosin in his research, which is encompassed under the umbrella topic of Actin. His Integrin study integrates concerns from other disciplines, such as Mechanotransduction, Fibronectin and Cell adhesion.
His primary areas of investigation include Cell biology, Biophysics, Actin, Cancer cell and Integrin. He studied Cell biology and Cytoskeleton that intersect with Mechanobiology. When carried out as part of a general Biophysics research project, his work on Myosin and Tropomyosin is frequently linked to work in Rigidity, therefore connecting diverse disciplines of study.
Michael P. Sheetz has included themes like Magnetic tweezers, Formins, Actin cytoskeleton and Protein filament in his Actin study. His work deals with themes such as Apoptosis and Rigidity, which intersect with Cancer cell. His Integrin research is multidisciplinary, incorporating perspectives in Vinculin, Focal adhesion and Mechanotransduction.
Michael P. Sheetz focuses on Cell biology, Extracellular matrix, Biophysics, Cytoskeleton and Integrin. He frequently studies issues relating to Cell growth and Cell biology. Michael P. Sheetz combines subjects such as Receptor tyrosine kinase and Myosin with his study of Extracellular matrix.
In his study, Actin cytoskeleton and Magnetic tweezers is inextricably linked to Actin, which falls within the broad field of Biophysics. His Cytoskeleton study combines topics from a wide range of disciplines, such as Adhesion, Kinetics, Binding site and Mechanobiology. Michael P. Sheetz has researched Integrin in several fields, including Cell adhesion molecule and Focal adhesion.
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Local force and geometry sensing regulate cell functions.
Viola Vogel;Michael Sheetz.
Nature Reviews Molecular Cell Biology (2006)
Identification of a novel force-generating protein, kinesin, involved in microtubule-based motility
Ronald D. Vale;Ronald D. Vale;Ronald D. Vale;Thomas S. Reese;Michael P. Sheetz;Michael P. Sheetz.
Biological Membranes as Bilayer Couples. A Molecular Mechanism of Drug-Erythrocyte Interactions
Michael P. Sheetz;S. J. Singer.
Proceedings of the National Academy of Sciences of the United States of America (1974)
Extracellular Matrix Rigidity Causes Strengthening of Integrin–Cytoskeleton Linkages
Daniel Choquet;Dan P Felsenfeld;Michael P Sheetz.
Stretching Single Talin Rod Molecules Activates Vinculin Binding
Armando del Rio;Raul Perez-Jimenez;Ruchuan Liu;Pere Roca-Cusachs.
Single particle tracking. Analysis of diffusion and flow in two-dimensional systems.
H. Qian;Michael Sheetz;E. L. Elson.
Biophysical Journal (1991)
The relationship between force and focal complex development
Catherine G. Galbraith;Kenneth M. Yamada;Michael P. Sheetz;Michael P. Sheetz.
Journal of Cell Biology (2002)
Tracking kinesin-driven movements with nanometre-scale precision
Jeff Gelles;Bruce J. Schnapp;Michael P. Sheetz.
Force Sensing by Mechanical Extension of the Src Family Kinase Substrate p130Cas
Yasuhiro Sawada;Masako Tamada;Benjamin J. Dubin-Thaler;Oksana Cherniavskaya.
Pilus retraction powers bacterial twitching motility.
Alexey J. Merz;Alexey J. Merz;Magdalene So;Michael P. Sheetz;Michael P. Sheetz.
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