World's Best Scientists 2026 revealed!

D-Index & Metrics

Molecular Biology

D-Index
53
Citations
9018
World Ranking
2395
National Ranking
14

Overview

Jie Yan is affiliated with the National University of Singapore in Singapore and has contributed extensively to the field of Biochemistry, Genetics and Molecular Biology, with a significant focus on Molecular Biology and Cell Biology. Their research output includes over 130 publications in these main fields, alongside work in Atomic and Molecular Physics, and Optics, Biomedical Engineering, and Physiology.

The research topics Jie Yan addresses cover several specialized areas. These include:

  • Cellular Mechanics and Interactions
  • Force Microscopy Techniques and Applications
  • Erythrocyte Function and Pathophysiology
  • Skin and Cellular Biology Research
  • Cell Adhesion Molecules Research
  • RNA Research and Splicing
  • Genomics and Chromatin Dynamics

Jie Yan has published repeatedly in several academic venues. The most frequent venues for their publications are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Journal of the American Chemical Society
  • Biophysical Journal
  • Proceedings of the National Academy of Sciences

Recent scientific contributions by Jie Yan include the following papers:

  • Force-Dependent Interactions between Talin and Full-Length Vinculin, 2021, Journal of the American Chemical Society
  • Talin mechanosensitivity is modulated by a direct interaction with cyclin-dependent kinase-1, 2021, Journal of Biological Chemistry
  • Mechanical instability of adherens junctions overrides intrinsic quiescence of hair follicle stem cells, 2021, Developmental Cell
  • Actin polymerisation and crosslinking drive left-right asymmetry in single cell and cell collectives, 2023, Nature Communications
  • Application of piconewton forces to individual filopodia reveals mechanosensory role of L-type Ca2+ channels, 2022, Biomaterials

Collaboration has been an important aspect of Jie Yan's work. Frequent co-authors include:

  • Shimin Le
  • Wenmao Huang
  • Benjamin T. Goult
  • Mingxi Yao
  • Xiaodan Zhao

Best Publications

  • Force-dependent conformational switch of α-catenin controls vinculin binding.

    Mingxi Yao;Wu Qiu;Ruchuan Liu;Artem K. Efremov

  • Mechanical activation of vinculin binding to talin locks talin in an unfolded conformation

    Mingxi Yao;Benjamin T. Goult;Hu Chen;Peiwen Cong

  • The mechanical response of talin

    Mingxi Yao;Benjamin T. Goult;Benjamin Klapholz;Xian Hu

  • Localized single-stranded bubble mechanism for cyclization of short double helix DNA.

    Jie Yan;John F. Marko

  • A divalent switch drives H-NS/DNA-binding conformations between stiffening and bridging modes.

    Yingjie Liu;Hu Chen;Linda J. Kenney;Linda J. Kenney;Jie Yan

  • Near-field-magnetic-tweezer manipulation of single DNA molecules.

    Jie Yan;Dunja Skoko;John F. Marko

  • Talin as a mechanosensitive signaling hub.

    Benjamin T. Goult;Jie Yan;Martin A. Schwartz;Martin A. Schwartz

  • Overstretching and force-driven strand separation of double-helix DNA.

    Simona Cocco;Jie Yan;Jean Francois Léger;Didier Chatenay

  • Improved High-Force Magnetic Tweezers for Stretching and Refolding of Proteins and Short DNA

    Hu Chen;Hongxia Fu;Xiaoying Zhu;Peiwen Cong

  • Mechanism of chromosome compaction and looping by the Escherichia coli nucleoid protein Fis.

    Dunja Skoko;Daniel Yoo;Hua Bai;Bernhard Schnurr

  • Dynamics of Equilibrium Folding and Unfolding Transitions of Titin Immunoglobulin Domain under Constant Forces

    Hu Chen;Guohua Yuan;Guohua Yuan;Ricksen S. Winardhi;Mingxi Yao

  • Statistics of loop formation along double helix DNAs.

    Jie Yan;Ryo Kawamura;John F. Marko

  • Revealing the competition between peeled ssDNA, melting bubbles, and S-DNA during DNA overstretching by single-molecule calorimetry

    Xinghua Zhang;Hu Chen;Shimin Le;Ioulia Rouzina

  • Two distinct overstretched DNA structures revealed by single-molecule thermodynamics measurements.

    Xinghua Zhang;Hu Chen;Hongxia Fu;Patrick S. Doyle

  • A kinetic proofreading mechanism for disentanglement of DNA by topoisomerases

    Jie Yan;Marcelo O. Magnasco;John F. Marko

  • The mechanotransduction machinery at work at adherens junctions.

    B. Ladoux;B. Ladoux;W. J. Nelson;J. Yan;R. M. Mège

  • Effects of DNA-distorting proteins on DNA elastic response.

    Jie Yan;John F. Marko

  • Defining a Centromere-like Element in Bacillus subtilis by Identifying the Binding Sites for the Chromosome-Anchoring Protein RacA

    Sigal Ben-Yehuda;Sigal Ben-Yehuda;Masya Fujita;Xiaole Shirley Liu;Boris Gorbatyuk

  • Two Distinct Overstretched DNA States

    Hongxia Fu;Hu Chen;John F. Marko;Jie Yan

  • Effect of YOYO-1 on the mechanical properties of DNA.

    Binu Kundukad;Jie Yan;Patrick S. Doyle;Patrick S. Doyle

Frequent Co-Authors

Michael P. Sheetz
Michael P. Sheetz The University of Texas Medical Branch at Galveston
John F. Marko
John F. Marko Northwestern University
Alexander D. Bershadsky
Alexander D. Bershadsky National University of Singapore
Benoit Ladoux
Benoit Ladoux Université Paris Cité
Chwee Teck Lim
Chwee Teck Lim National University of Singapore
Hanry Yu
Hanry Yu National University of Singapore
René-Marc Mège
René-Marc Mège Université Paris Cité
Jay T. Groves
Jay T. Groves University of California, Berkeley
Kunio Takeyasu
Kunio Takeyasu Kyoto University

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring Molecular Biology can lead to diverse opportunities in healthcare and research. For those interested in combining biology with patient care, online nursing programs offer flexible paths. Accelerated BSN programs for non nurses allow students with non-nursing backgrounds to quickly transition into nursing careers, making it easier for science majors to expand their options.

Current RNs can advance even faster with the fastest RN to BSN program, sometimes completing their degrees in as little as six months. For those aiming to specialize, nurse practitioner roles are in high demand, especially in mental health fields. Interested individuals often ask, how long does it take to become a nurse practitioner? The answer varies, but accelerated paths can help you reach your career goals more quickly.

Careers like psychiatric mental health nurse practitioner are particularly rewarding, both personally and financially. Explore psychiatric mental health nurse practitioner salary by state to understand potential earnings. Whether focusing on research or patient care, these online options make it easier for molecular biology students to broaden their horizons and enter thriving fields.

Best Scientists Citing Jie Yan

Trending Scientists