World's Best Scientists 2026 revealed!
René-Marc Mège

René-Marc Mège

D-Index & Metrics

Biology and Biochemistry

D-Index
56
Citations
11370
World Ranking
14427
National Ranking
558

Overview

René-Marc Mège is affiliated with Université Paris Cité in France and has a substantial body of research primarily within the fields of Biochemistry, Genetics and Molecular Biology, and Engineering. Their work spans several subfields including Cell Biology, Biomedical Engineering, Molecular Biology, Condensed Matter Physics, and Atomic and Molecular Physics, and Optics.

The scientist's main areas of investigation focus extensively on Cellular Mechanics and Interactions, with significant contributions to related topics such as 3D Printing in Biomedical Research, Micro and Nano Robotics, Force Microscopy Techniques and Applications, Microfluidic and Bio-sensing Technologies, Biocrusts and Microbial Ecology, and Microtubule and mitosis dynamics.

Among their recent papers are:

  • Cell response to substrate rigidity is regulated by active and passive cytoskeletal stress, 2020, Proceedings of the National Academy of Sciences
  • The role of single-cell mechanical behaviour and polarity in driving collective cell migration, 2020, Nature Physics
  • Investigating the nature of active forces in tissues reveals how contractile cells can form extensile monolayers, 2021, Nature Materials
  • Cell migration guided by long-lived spatial memory, 2021, Nature Communications
  • Mechanical stress driven by rigidity sensing governs epithelial stability, 2022, Nature Physics

René-Marc Mège's collaborations have involved several frequent co-authors, highlighting a network of scientific interaction and joint studies. These include:

  • Benoît Ladoux
  • Lakshmi Balasubramaniam
  • Tien Dang
  • Raphaël Voituriez
  • Amin Doostmohammadi

Their research has been published consistently across multiple venues with a high frequency in publications such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Physics
  • Nature Materials
  • Nature Communications
  • Biology of the Cell

Best Publications

  • E-Cadherin Is the Receptor for Internalin, a Surface Protein Required for Entry of L. monocytogenes into Epithelial Cells

    Jérôme Mengaud;Hélène Ohayon;Pierre Gounon;René-Marc Mège

  • Mechanobiology of collective cell behaviours.

    Benoit Ladoux;René-Marc Mège

  • Force-dependent conformational switch of α-catenin controls vinculin binding.

    Mingxi Yao;Wu Qiu;Ruchuan Liu;Artem K. Efremov

  • Construction of epithelioid sheets by transfection of mouse sarcoma cells with cDNAs for chicken cell adhesion molecules.

    Rene-Marc Mege;Fumio Matsuzaki;Warren J. Gallin;Jeff I. Goldberg

  • Regulation of cell-cell junctions by the cytoskeleton.

    René-Marc Mège;Julie Gavard;Mireille Lambert

  • Adaptive rheology and ordering of cell cytoskeleton govern matrix rigidity sensing

    Mukund Gupta;Bibhu Ranjan Sarangi;Joran Deschamps;Yasaman Nematbakhsh

  • Strength Dependence of Cadherin-Mediated Adhesions

    Benoit Ladoux;Benoit Ladoux;Ester Anon;Mireille Lambert;Mireille Lambert;Aleksandr Rabodzey

  • Cell sorting-out is modulated by both the specificity and amount of different cell adhesion molecules (CAMs) expressed on cell surfaces.

    David R. Friedlander;Rene-Marc Mege;Bruce A. Cunningham;Gerald M. Edelman

  • Meningococcal Type IV Pili Recruit the Polarity Complex to Cross the Brain Endothelium

    Mathieu Coureuil;Guillain Mikaty;Florence Miller;Florence Miller;Hervé Lécuyer;Hervé Lécuyer

  • Traction forces exerted through N-cadherin contacts.

    Arthur Ganz;Mireille Lambert;Alexandre Saez;Pascal Silberzan

  • Integration of Cadherin Adhesion and Cytoskeleton at Adherens Junctions.

    René Marc Mège;Noboru Ishiyama

  • α-Catenin and Vinculin Cooperate to Promote High E-cadherin-based Adhesion Strength

    William A. Thomas;Cécile Boscher;Cécile Boscher;Yeh Shiu Chu;Damien Cuvelier

  • Remodeling the zonula adherens in response to tension and the role of afadin in this response

    Wangsun Choi;Bipul R. Acharya;Grégoire Peyret;Marc Antoine Fardin

  • Front–Rear Polarization by Mechanical Cues: From Single Cells to Tissues

    Benoit Ladoux;Benoit Ladoux;René-Marc Mège;Xavier Trepat

  • N-cadherin and N-CAM in myoblast fusion: compared localisation and effect of blockade by peptides and antibodies

    R.M. Mege;D. Goudou;C. Diaz;M. Nicolet

  • Cadherin expression is required for the spread of Shigella flexneri between epithelial cells

    Philippe J. Sansonetti;Joëlle Mounier;Marle Christine Prévost;René-Marc Mège

  • Cellular expression of liver and neural cell adhesion molecules after transfection with their cDNAs results in specific cell-cell binding.

    Gerald M. Edelman;Ben A. Murray;Rene-Marc Mege;Bruce A. Cunningham

  • Nanoscale architecture of cadherin-based cell adhesions

    Cristina Bertocchi;Yilin Wang;Andrea Ravasio;Yusuke Hara

  • Immobilized dimers of N-cadherin-Fc chimera mimic cadherin-mediated cell contact formation: contribution of both outside-in and inside-out signals

    Mireille Lambert;Françoise Padilla;René Marc Mège

  • A Molecular Clutch between the Actin Flow and N-Cadherin Adhesions Drives Growth Cone Migration

    Lucie Bard;Cécile Boscher;Mireille Lambert;René-Marc Mège

Frequent Co-Authors

Benoit Ladoux
Benoit Ladoux Université Paris Cité
Chwee Teck Lim
Chwee Teck Lim National University of Singapore
Julie Gavard
Julie Gavard University of Nantes
Jie Yan
Jie Yan National University of Singapore
Michael P. Sheetz
Michael P. Sheetz The University of Texas Medical Branch at Galveston
Gerald M. Edelman
Gerald M. Edelman Neurosciences Institute
Julia M. Yeomans
Julia M. Yeomans University of Oxford
Daniel Choquet
Daniel Choquet University of Bordeaux
André Sobel
André Sobel Grenoble Alpes University
Bruce A. Cunningham
Bruce A. Cunningham Scripps Research Institute

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