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Biology and Biochemistry

D-Index
84
Citations
21901
World Ranking
3377
National Ranking
255

Overview

Bruce Caterson is affiliated with Cardiff University in the United Kingdom and has contributed to research primarily within the fields of Biochemistry, Genetics and Molecular Biology as well as Medicine. Their work spans several key subfields, including Molecular Biology, Cell Biology, Genetics, Periodontics, and Otorhinolaryngology.

Their research focuses on a variety of topics related to proteoglycans and glycosaminoglycans, congenital heart defects, connective tissue disorders, oral health pathology and treatment, head and neck cancer studies, peptidase inhibition and analysis, and ubiquitin and proteasome pathways.

Notable recent publications by Bruce Caterson include:

  • Vascular dimorphism ensured by regulated proteoglycan dynamics favors rapid umbilical artery closure at birth, 2020, eLife
  • Monoclonal antibodies recognizing protease-generated neoepitopes from cartilage proteoglycan degradation: application to studies of human link protein cleavage by stromelysin, 2021, UNC Libraries
  • The dynamic structure of the pericellular matrix on living cells, 2020, UNC Libraries
  • Vascular dimorphism ensured by regulated proteoglycan dynamics favors rapid umbilical artery closure at birth, 2020, bioRxiv (Cold Spring Harbor Laboratory)
  • Neutrophil collagenase (MMP-8) cleaves at the aggrecanase site E 373 -A 374 in the interglobular domain of cartilage aggrecan, 2020, UNC Libraries

Bruce Caterson frequently collaborates with several researchers, including:

  • Clare Hughes
  • Suneel Apte
  • Sumeda Nandadasa
  • Jason M. Szafron
  • Vai Pathak

Their findings have been published across multiple venues, predominantly in UNC Libraries, with additional publications appearing in eLife and bioRxiv (Cold Spring Harbor Laboratory).

Best Publications

  • Matrix metalloproteinases and aggrecanase: Their role in disorders of the human intervertebral disc

    Sally Roberts;Bruce Caterson;Janis Menage;E. Helena Evans

  • Mapping by monoclonal antibody detection of glycosaminoglycans in connective tissues

    John R. Couchman;Bruce Caterson;James E. Christner;John R. Baker

  • Identification of a monoclonal antibody that specifically recognizes corneal and skeletal keratan sulfate. Monoclonal antibodies to cartilage proteoglycan

    B Caterson;J E Christner;J R Baker

  • Effects of mechanical loading on the tissues of the rabbit knee.

    E. L. Radin;R. B. Martin;David Burr;B. Caterson

  • The role of synovial macrophages and macrophage‐produced mediators in driving inflammatory and destructive responses in osteoarthritis

    Jan Bondeson;Arjen B. Blom;Shane Daniel Wainwright;Clare Hughes

  • Articular Cartilage Superficial Zone Protein (SZP) Is Homologous to Megakaryocyte Stimulating Factor Precursor and Is a Multifunctional Proteoglycan with Potential Growth-Promoting, Cytoprotective, and Lubricating Properties in Cartilage Metabolism

    Carl R. Flannery;Clare E. Hughes;Barbara L. Schumacher;Debbie Tudor

  • Mechanical determinants of osteoarthrosis.

    E. L. Radin;D. B. Burr;B. Caterson;David P Fyhrie

  • Production and characterization of monoclonal antibodies directed against connective tissue proteoglycans.

    Caterson B;Christner Je;Baker;Couchman

  • Mechanisms involved in cartilage proteoglycan catabolism.

    Bruce Caterson;Carl R. Flannery;Clare Elizabeth Hughes;Chris B. Little

  • n-3 Fatty Acids Specifically Modulate Catabolic Factors Involved in Articular Cartilage Degradation *

    Clare L. Curtis;Clare Elizabeth Hughes;C. R. Flannery;Chris B. Little

  • Quantification of keratan sulfate in blood as a marker of cartilage catabolism.

    Eugene J‐ M. A. Thonar;Mary Ellen Lenz;Gordon K. Klintworth;Bruce Caterson

  • Repair of human articular cartilage after implantation of autologous chondrocytes

    J. B. Richardson;B. Caterson;E. H. Evans;B. A. Ashton

  • The role of human HtrA1 in arthritic disease.

    Sandra Grau;Peter J. Richards;Briedgeen Kerr;Clare Elizabeth Hughes

  • Monoclonal antibodies that specifically recognize neoepitope sequences generated by 'aggrecanase' and matrix metalloproteinase cleavage of aggrecan: application to catabolism in situ and in vitro.

    C E Hughes;B Caterson;A J Fosang;P J Roughley

  • Proteolytic Activities of Human ADAMTS-5 COMPARATIVE STUDIES WITH ADAMTS-4

    Christi Gendron;Masahide Kashiwagi;Ngee Han Lim;Jan J. Enghild

  • The antigenic determinants recognized by three monoclonal antibodies to keratan sulphate involve sulphated hepta- or larger oligosaccharides of the poly(N-acetyllactosamine) series

    Huseyin Mehmet;Peter Scudder;Ping W. Tang;Elizabeth F. Hounsell

  • Immunodetection and partial cDNA sequence of the proteoglycan, superficial zone protein, synthesized by cells lining synovial joints.

    Barbara L. Schumacher;Clare E. Hughes;Klaus E. Kuettner;Bruce Caterson

  • Modulation of native chondroitin sulphate structure in tissue development and in disease.

    B. Caterson;F. Mahmoodian;J.M. Sorrell;T.E. Hardingham

  • Altered proteolytic activities of ADAMTS-4 expressed by C-terminal processing

    Masahide Kashiwagi;Jan J. Enghild;Christi Gendron;Clare Hughes

  • Aggrecanase versus matrix metalloproteinases in the catabolism of the interglobular domain of aggrecan in vitro.

    Chris B. Little;Carl R. Flannery;Clare E. Hughes;John S. Mort

Frequent Co-Authors

Clare Elizabeth Hughes
Clare Elizabeth Hughes Cardiff University
Christopher B. Little
Christopher B. Little University of Sydney
John L. Harwood
John L. Harwood Cardiff University
Hideaki Nagase
Hideaki Nagase University of Oxford
Jan J. Enghild
Jan J. Enghild Aarhus University
Brian Johnstone
Brian Johnstone Oregon Health & Science University
Peter J. Roughley
Peter J. Roughley McGill University
Mitsuo Yamauchi
Mitsuo Yamauchi University of North Carolina at Chapel Hill
Timothy E. Hardingham
Timothy E. Hardingham Wellcome Centre for Cell-Matrix Research
John S. Mort
John S. Mort McGill University

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