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Jan J. Enghild

Jan J. Enghild

D-Index & Metrics

Biology and Biochemistry

D-Index
84
Citations
31063
World Ranking
3268
National Ranking
33

Overview

Jan J. Enghild is affiliated with Aarhus University in Denmark and has contributed extensively to the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their research encompasses various subfields, including Molecular Biology, Immunology, Cancer Research, Radiology, Nuclear Medicine and Imaging, and Physiology.

Enghild's work addresses key topics such as:

  • Protease and Inhibitor Mechanisms
  • Cell Adhesion Molecules Research
  • Peptidase Inhibition and Analysis
  • Oral microbiology and periodontitis research
  • Corneal Surgery and Treatments
  • Corneal surgery and disorders
  • Signaling Pathways in Disease

Their recent publications include the following papers:

  • Mapping and identification of soft corona proteins at nanoparticles and their impact on cellular association (2020, Nature Communications)
  • STEEP mediates STING ER exit and activation of signaling (2020, Nature Immunology)
  • SARS-CoV-2 evades immune detection in alveolar macrophages (2020, EMBO Reports)
  • Structural and functional insights into oligopeptide acquisition by the RagAB transporter from Porphyromonas gingivalis (2020, Nature Microbiology)
  • Biochemical mechanisms of aggregation in TGFBI-linked corneal dystrophies (2020, Progress in Retinal and Eye Research)

Frequent co-authors collaborating with Enghild include:

  • Carsten Scavenius
  • Ida B. Thøgersen
  • Nadia Sukusu Nielsen
  • Seandean L. Harwood
  • Jan Potempa

The frequent publication venues for Enghild's research are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Biological Chemistry
  • Nature Communications
  • Biochemistry
  • Nature Immunology

Best Publications

  • Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease.

    Warren J. Strittmatter;Ann M. Saunders;Donald Schmechel;Margaret Pericak-Vance

  • Matrix metalloproteinase 3 (stromelysin) activates the precursor for the human matrix metalloproteinase 9.

    Y Ogata;J.J. Enghild;H Nagase

  • Angiostatin binds ATP synthase on the surface of human endothelial cells

    Tammy L. Moser;M. Sharon Stack;Iain Asplin;Jan J. Enghild

  • Mechanisms of activation of tissue procollagenase by matrix metalloproteinase 3 (stromelysin).

    Ko Suzuki;Jan J. Enghild;Tatsuhisa Morodomi;Guy Salvesen

  • Huntingtin and DRPLA proteins selectively interact with the enzyme GAPDH.

    James R. Burke;Jan J. Enghild;Margaret E. Martin;Yuh Shan Jou

  • Degradation of interleukin 1beta by matrix metalloproteinases.

    Akira Ito;Akihira Mukaiyama;Yoshifumi Itoh;Hideaki Nagase

  • MATRIX METALLOPROTEINASE 2 FROM HUMAN RHEUMATOID SYNOVIAL FIBROBLASTS : PURIFICATION AND ACTIVATION OF THE PRECURSOR AND ENZYMIC PROPERTIES

    Yasunori Okada;Tatsuhisa Morodomi;Jan J. Enghild;Ko Suzuki

  • Stepwise activation mechanisms of the precursor of matrix metalloproteinase 3 (stromelysin) by proteinases and (4-aminophenyl)mercuric acetate.

    Hideaki Nagase;Jan J. Enghild;Ko Suzuki;Guy Salvesen

  • Matrix metalloproteinases degrade insulin-like growth factor-binding protein-3 in dermal fibroblast cultures.

    J L Fowlkes;J J Enghild;K Suzuki;H Nagase

  • The mechanism of cancer-mediated conversion of plasminogen to the angiogenesis inhibitor angiostatin

    S Gately;P Twardowski;M S Stack;D L Cundiff

  • Functional amyloid in Pseudomonas.

    Morten Simonsen Dueholm;Steen V. Petersen;Mads Sønderkær;Poul Larsen

  • Proteolytic Activities of Human ADAMTS-5 COMPARATIVE STUDIES WITH ADAMTS-4

    Christi Gendron;Masahide Kashiwagi;Ngee Han Lim;Jan J. Enghild

  • Spider genomes provide insight into composition and evolution of venom and silk

    Kristian W. Sanggaard;Jesper S. Bechsgaard;Xiaodong Fang;Jinjie Duan

  • Analysis of the plasma elimination kinetics and conformational stabilities of native, proteinase-complexed, and reactive site cleaved serpins: comparison of alpha 1-proteinase inhibitor, alpha 1-antichymotrypsin, antithrombin III, alpha 2-antiplasmin, angiotensinogen, and ovalbumin.

    Alan E. Mast;Jan J. Enghild;Salvatore V. Pizzo;Guy Salvesen

  • Desmosome signaling. Inhibition of p38MAPK prevents pemphigus vulgaris IgG-induced cytoskeleton reorganization.

    Paula Berkowitz;Peiqi Hu;Zhi Liu;Luis A. Diaz

  • Human Prostate Carcinoma Cells Express Enzymatic Activity That Converts Human Plasminogen to the Angiogenesis Inhibitor, Angiostatin

    Stephen Gately;Przemyslaw Twardowski;M. Sharon Stack;Matthew Patrick

  • The role of stable α-synuclein oligomers in the molecular events underlying amyloid formation.

    Nikolai Lorenzen;Søren Bang Nielsen;Alexander K. Buell;Jørn Døvling Kaspersen

  • Purification and Characterization of Mouse Soluble Receptor for Advanced Glycation End Products (sRAGE)

    Lana E. Hanford;Jan J. Enghild;Zuzana Valnickova;Steen V. Petersen

  • Altered proteolytic activities of ADAMTS-4 expressed by C-terminal processing

    Masahide Kashiwagi;Jan J. Enghild;Christi Gendron;Clare Hughes

  • Analysis of inter-alpha-trypsin inhibitor and a novel trypsin inhibitor, pre-alpha-trypsin inhibitor, from human plasma. Polypeptide chain stoichiometry and assembly by glycan.

    J J Enghild;I B Thøgersen;S V Pizzo;G Salvesen

Frequent Co-Authors

Jan Potempa
Jan Potempa University of Louisville
Guy S. Salvesen
Guy S. Salvesen Sanford Burnham Prebys Medical Discovery Institute
Daniel E. Otzen
Daniel E. Otzen Aarhus University
Tim D. Oury
Tim D. Oury University of Pittsburgh
Salvatore V. Pizzo
Salvatore V. Pizzo Duke University
Hideaki Nagase
Hideaki Nagase University of Oxford
Torsten Nygaard Kristensen
Torsten Nygaard Kristensen Aalborg University
Peter Højrup
Peter Højrup University of Southern Denmark
Niels Chr. Nielsen
Niels Chr. Nielsen Aarhus University
James D. Crapo
James D. Crapo National Jewish Health

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