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Medicine

D-Index
87
Citations
56037
World Ranking
13376
National Ranking
1248

Overview

Ann M. Saunders is affiliated with Durham University in the United Kingdom, with an academic focus centered primarily within the field of Medicine. Their research has a strong emphasis on neurological and genetic aspects of neurodegenerative diseases, as reflected in the subfields of Neurology, Molecular Biology, Genetics, Psychiatry and Mental Health, and Physiology.

Their work covers a range of topics related to neurodegenerative disorders and muscle diseases, including Amyotrophic Lateral Sclerosis (ALS) Research, Neurogenetic and Muscular Disorders Research, Dementia and Cognitive Impairment Research, Alzheimer's Disease research and treatments, and Parkinson's Disease mechanisms and treatments. In addition, some research addresses specific biological compounds such as Ginkgo biloba and Cashew Applications, as well as Cholinesterase and its role in neurodegenerative diseases.

Recent academic papers authored or co-authored by Ann M. Saunders include:

  • Safety and efficacy of pioglitazone for the delay of cognitive impairment in people at risk of Alzheimer's disease (TOMMORROW): a prognostic biomarker study and a phase 3, randomised, double-blind, placebo-controlled trial (2021, The Lancet Neurology)
  • Structural Variants May Be a Source of Missing Heritability in sALS (2020, Frontiers in Neuroscience)
  • Reassessment of Pioglitazone for Alzheimer's Disease (2021, Frontiers in Neuroscience)
  • Novel STMN2 Variant Linked to Amyotrophic Lateral Sclerosis Risk and Clinical Phenotype (2021, Frontiers in Aging Neuroscience)
  • Association of a structural variant within the SQSTM1 gene with amyotrophic lateral sclerosis (2020, Neurology Genetics)

Ann M. Saunders has frequently collaborated with other researchers, including Daniel K. Burns, Robert Alexander, Stephen Haneline, Frances Theunissen, and Loren L. Flynn. These co-authors have contributed to several publications alongside Saunders, indicating a network of research activity focused on neurodegenerative diseases and genetic studies.

The scientist's work has been published in journals and venues such as:

  • Frontiers in Neuroscience
  • Neurology Genetics
  • The Lancet Neurology
  • Frontiers in Aging Neuroscience
  • Journal of Alzheimer's Disease

Best Publications

  • Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

    E. H. Corder;A. M. Saunders;W. J. Strittmatter;D. E. Schmechel

  • Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease.

    Warren J. Strittmatter;Ann M. Saunders;Donald Schmechel;Margaret Pericak-Vance

  • Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease.

    A. M. Saunders;W. J. Strittmatter;D. Schmechel;P. H. St. George-Hyslop

  • Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease.

    Corder Eh;Saunders Am;Risch Nj;Strittmatter Wj

  • Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease

    D E Schmechel;A M Saunders;W J Strittmatter;B J Crain

  • Binding of human apolipoprotein E to synthetic amyloid beta peptide: isoform-specific effects and implications for late-onset Alzheimer disease

    Warren J. Strittmatter;Karl H. Weisgraber;David Y. Huang;Li Ming Dong

  • Patterns of brain activation in people at risk for Alzheimer's disease

    Susan Y. Bookheimer;Magdalena H. Strojwas;Mark S. Cohen;Ann M. Saunders

  • Functional brain abnormalities in young adults at genetic risk for late-onset Alzheimer's dementia

    Eric M. Reiman;Kewei Chen;Gene E. Alexander;Gene E. Alexander;Richard J. Caselli;Richard J. Caselli

  • Identification of miRNA Changes in Alzheimer's Disease Brain and CSF Yields Putative Biomarkers and Insights into Disease Pathways

    John P. Cogswell;James Ward;Ian A. Taylor;Michelle Waters

  • Efficacy of rosiglitazone in a genetically defined population with mild-to-moderate Alzheimer's disease.

    M E Risner;A M Saunders;J F B Altman;G C Ormandy

  • Cerebral metabolic and cognitive decline in persons at genetic risk for Alzheimer's disease

    Gary W. Small;Linda M. Ercoli;Daniel H. S. Silverman;S.-C. Huang

  • Clinicopathologic studies in cognitively healthy aging and Alzheimer's disease: relation of histologic markers to dementia severity, age, sex, and apolipoprotein E genotype.

    Berg L;McKeel Dw;Miller Jp;Storandt M

  • Utility of the Apolipoprotein E Genotype in the Diagnosis of Alzheimer's Disease

    Richard Mayeux;Ann M. Saunders;Steven Shea;Suzanne Mirra

  • Apolipoprotein E ∈4 allele distributions in late-onset Alzheimer's disease and in other amyloid-forming diseases

    A. M. Saunders;A. D. Roses;M. A. Pericak-Vance;K. C. Dole

  • Isoform-specific interactions of apolipoprotein E with microtubule-associated protein tau: implications for Alzheimer disease

    Warren J. Strittmatter;Ann M. Saunders;Michel Goedert;Karl H. Weisgraber

  • Candidate single-nucleotide polymorphisms from a genomewide association study of Alzheimer disease

    Hao Li;Sally Wetten;Li Li;Pamela L. St. Jean

  • Delayed onset of Alzheimer's disease with nonsteroidal anti-inflammatory and histamine H2 blocking drugs

    John C.S. Breitner;Kathleen A. Welsh;Michael J. Helms;Perry C. Gaskell

  • Hypothesis: Microtubule Instability and Paired Helical Filament Formation in the Alzheimer Disease Brain Are Related to Apolipoprotein E Genotype

    Warren J. Strittmatter;Karl H. Weisgraber;Michel Goedert;Ann M. Saunders

  • Apolipoprotein E associates with beta amyloid peptide of Alzheimer's disease to form novel monofibrils. Isoform apoE4 associates more efficiently than apoE3.

    D A Sanan;K H Weisgraber;S J Russell;R W Mahley

  • Complete genomic screen in late-onset familial Alzheimer disease. Evidence for a new locus on chromosome 12.

    Margaret A. Pericak-Vance;Meredyth P. Bass;Larry H. Yamaoka;Perry C. Gaskell

Frequent Co-Authors

Allen D. Roses
Allen D. Roses Duke University
Margaret A. Pericak-Vance
Margaret A. Pericak-Vance University of Miami
Warren J. Strittmatter
Warren J. Strittmatter Duke University
Gary W. Small
Gary W. Small University of California, Los Angeles
William K. Scott
William K. Scott University of Miami
Christine M. Hulette
Christine M. Hulette Duke University
John R. Gilbert
John R. Gilbert University of Miami
Eric M. Reiman
Eric M. Reiman Arizona State University
Jeffery M. Vance
Jeffery M. Vance University of Miami

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