Her primary scientific interests are in Apolipoprotein E, Alzheimer's disease, Allele, Internal medicine and Genetics. The study incorporates disciplines such as Central nervous system disease, Senile plaques, Biochemistry, Posterior cingulate and Risk factor in addition to Apolipoprotein E. The Alzheimer's disease study combines topics in areas such as Age of onset, Dementia, Genotype and Degenerative disease.
The various areas that Ann M. Saunders examines in her Allele study include SORL1 and Late onset. Her research in SORL1 focuses on subjects like PSEN2, which are connected to Pathogenesis. Her research integrates issues of Gastroenterology, Endocrinology, Cognition and Cardiology in her study of Internal medicine.
Apolipoprotein E, Disease, Alzheimer's disease, Internal medicine and Genetics are her primary areas of study. Her work deals with themes such as Dementia, Allele, Genotype and Age of onset, which intersect with Apolipoprotein E. Her studies in Allele integrate themes in fields like Immunology, Gerontology and Risk factor.
Her research in Disease intersects with topics in Clinical trial, Bioinformatics and Intensive care medicine. Her biological study spans a wide range of topics, including Cognition, Posterior cingulate and Central nervous system disease, Degenerative disease. Her Internal medicine research includes elements of Gastroenterology, Endocrinology and Oncology.
Her scientific interests lie mostly in Disease, Apolipoprotein E, Internal medicine, Genetics and Clinical trial. Her Disease research incorporates elements of Odds ratio, Gene and Bioinformatics. Her Apolipoprotein E research includes themes of Dementia, Haplotype, Genotype, Age of onset and Alzheimer's disease.
Pathology covers she research in Alzheimer's disease. As a member of one scientific family, Ann M. Saunders mostly works in the field of Internal medicine, focusing on Oncology and, on occasion, Allele, Cohort, Sanger sequencing and Amyotrophic lateral sclerosis. Her Late onset research is multidisciplinary, relying on both Peroxisome proliferator-activated receptor and Endocrinology, Pathophysiology.
Ann M. Saunders spends much of her time researching Apolipoprotein E, Genetics, Alzheimer's disease, Mitochondrion and Haplotype. Her studies deal with areas such as Physiology, Allele and Age of onset as well as Apolipoprotein E. Her Physiology research includes elements of Pharmacology and Pathology.
Ann M. Saunders interconnects Allele frequency and Ethnic populations in the investigation of issues within Age of onset. Ann M. Saunders works on Genetics which deals in particular with Linkage disequilibrium. Her biological study spans a wide range of topics, including Dementia and Cohort study.
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Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families
E. H. Corder;A. M. Saunders;W. J. Strittmatter;D. E. Schmechel.
Science (1993)
Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease.
Warren J. Strittmatter;Ann M. Saunders;Donald Schmechel;Margaret Pericak-Vance.
Proceedings of the National Academy of Sciences of the United States of America (1993)
Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease.
A. M. Saunders;W. J. Strittmatter;D. Schmechel;P. H. St. George-Hyslop.
Neurology (1993)
Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease.
Corder Eh;Saunders Am;Risch Nj;Strittmatter Wj.
Nature Genetics (1994)
Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease
D E Schmechel;A M Saunders;W J Strittmatter;B J Crain.
Proceedings of the National Academy of Sciences of the United States of America (1993)
Binding of human apolipoprotein E to synthetic amyloid beta peptide: isoform-specific effects and implications for late-onset Alzheimer disease
Warren J. Strittmatter;Karl H. Weisgraber;David Y. Huang;Li Ming Dong.
Proceedings of the National Academy of Sciences of the United States of America (1993)
Patterns of brain activation in people at risk for Alzheimer's disease
Susan Y. Bookheimer;Magdalena H. Strojwas;Mark S. Cohen;Ann M. Saunders.
The New England Journal of Medicine (2000)
Functional brain abnormalities in young adults at genetic risk for late-onset Alzheimer's dementia
Eric M. Reiman;Kewei Chen;Gene E. Alexander;Gene E. Alexander;Richard John Caselli;Richard John Caselli.
Proceedings of the National Academy of Sciences of the United States of America (2004)
Efficacy of rosiglitazone in a genetically defined population with mild-to-moderate Alzheimer's disease.
M E Risner;A M Saunders;J F B Altman;G C Ormandy.
Pharmacogenomics Journal (2006)
Identification of miRNA Changes in Alzheimer's Disease Brain and CSF Yields Putative Biomarkers and Insights into Disease Pathways
John P. Cogswell;James Ward;Ian A. Taylor;Michelle Waters.
Journal of Alzheimer's Disease (2008)
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