D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Medicine D-index 74 Citations 44,764 158 World Ranking 12513 National Ranking 1122

Overview

What is she best known for?

The fields of study she is best known for:

  • Gene
  • Internal medicine
  • Alzheimer's disease

Her primary scientific interests are in Apolipoprotein E, Alzheimer's disease, Allele, Internal medicine and Genetics. The study incorporates disciplines such as Central nervous system disease, Senile plaques, Biochemistry, Posterior cingulate and Risk factor in addition to Apolipoprotein E. The Alzheimer's disease study combines topics in areas such as Age of onset, Dementia, Genotype and Degenerative disease.

The various areas that Ann M. Saunders examines in her Allele study include SORL1 and Late onset. Her research in SORL1 focuses on subjects like PSEN2, which are connected to Pathogenesis. Her research integrates issues of Gastroenterology, Endocrinology, Cognition and Cardiology in her study of Internal medicine.

Her most cited work include:

  • Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families (7112 citations)
  • Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease. (3560 citations)
  • Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease. (3218 citations)

What are the main themes of her work throughout her whole career to date?

Apolipoprotein E, Disease, Alzheimer's disease, Internal medicine and Genetics are her primary areas of study. Her work deals with themes such as Dementia, Allele, Genotype and Age of onset, which intersect with Apolipoprotein E. Her studies in Allele integrate themes in fields like Immunology, Gerontology and Risk factor.

Her research in Disease intersects with topics in Clinical trial, Bioinformatics and Intensive care medicine. Her biological study spans a wide range of topics, including Cognition, Posterior cingulate and Central nervous system disease, Degenerative disease. Her Internal medicine research includes elements of Gastroenterology, Endocrinology and Oncology.

She most often published in these fields:

  • Apolipoprotein E (66.12%)
  • Disease (35.12%)
  • Alzheimer's disease (35.54%)

What were the highlights of her more recent work (between 2013-2021)?

  • Disease (35.12%)
  • Apolipoprotein E (66.12%)
  • Internal medicine (32.23%)

In recent papers she was focusing on the following fields of study:

Her scientific interests lie mostly in Disease, Apolipoprotein E, Internal medicine, Genetics and Clinical trial. Her Disease research incorporates elements of Odds ratio, Gene and Bioinformatics. Her Apolipoprotein E research includes themes of Dementia, Haplotype, Genotype, Age of onset and Alzheimer's disease.

Pathology covers she research in Alzheimer's disease. As a member of one scientific family, Ann M. Saunders mostly works in the field of Internal medicine, focusing on Oncology and, on occasion, Allele, Cohort, Sanger sequencing and Amyotrophic lateral sclerosis. Her Late onset research is multidisciplinary, relying on both Peroxisome proliferator-activated receptor and Endocrinology, Pathophysiology.

Between 2013 and 2021, her most popular works were:

  • Alzheimer's disease susceptibility genes APOE and TOMM40, and brain white matter integrity in the Lothian Birth Cohort 1936. (54 citations)
  • New applications of disease genetics and pharmacogenetics to drug development. (46 citations)
  • The Broad Impact of TOM40 on Neurodegenerative Diseases in Aging. (45 citations)

In her most recent research, the most cited papers focused on:

  • Gene
  • Internal medicine
  • Genetics

Ann M. Saunders spends much of her time researching Apolipoprotein E, Genetics, Alzheimer's disease, Mitochondrion and Haplotype. Her studies deal with areas such as Physiology, Allele and Age of onset as well as Apolipoprotein E. Her Physiology research includes elements of Pharmacology and Pathology.

Ann M. Saunders interconnects Allele frequency and Ethnic populations in the investigation of issues within Age of onset. Ann M. Saunders works on Genetics which deals in particular with Linkage disequilibrium. Her biological study spans a wide range of topics, including Dementia and Cohort study.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

E. H. Corder;A. M. Saunders;W. J. Strittmatter;D. E. Schmechel.
Science (1993)

9267 Citations

Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease.

Warren J. Strittmatter;Ann M. Saunders;Donald Schmechel;Margaret Pericak-Vance.
Proceedings of the National Academy of Sciences of the United States of America (1993)

4867 Citations

Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease.

A. M. Saunders;W. J. Strittmatter;D. Schmechel;P. H. St. George-Hyslop.
Neurology (1993)

4247 Citations

Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease.

Corder Eh;Saunders Am;Risch Nj;Strittmatter Wj.
Nature Genetics (1994)

1952 Citations

Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease

D E Schmechel;A M Saunders;W J Strittmatter;B J Crain.
Proceedings of the National Academy of Sciences of the United States of America (1993)

1697 Citations

Binding of human apolipoprotein E to synthetic amyloid beta peptide: isoform-specific effects and implications for late-onset Alzheimer disease

Warren J. Strittmatter;Karl H. Weisgraber;David Y. Huang;Li Ming Dong.
Proceedings of the National Academy of Sciences of the United States of America (1993)

1597 Citations

Patterns of brain activation in people at risk for Alzheimer's disease

Susan Y. Bookheimer;Magdalena H. Strojwas;Mark S. Cohen;Ann M. Saunders.
The New England Journal of Medicine (2000)

1381 Citations

Functional brain abnormalities in young adults at genetic risk for late-onset Alzheimer's dementia

Eric M. Reiman;Kewei Chen;Gene E. Alexander;Gene E. Alexander;Richard John Caselli;Richard John Caselli.
Proceedings of the National Academy of Sciences of the United States of America (2004)

959 Citations

Efficacy of rosiglitazone in a genetically defined population with mild-to-moderate Alzheimer's disease.

M E Risner;A M Saunders;J F B Altman;G C Ormandy.
Pharmacogenomics Journal (2006)

870 Citations

Identification of miRNA Changes in Alzheimer's Disease Brain and CSF Yields Putative Biomarkers and Insights into Disease Pathways

John P. Cogswell;James Ward;Ian A. Taylor;Michelle Waters.
Journal of Alzheimer's Disease (2008)

866 Citations

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