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Genetics
USA
2026

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Genetics

D-Index
152
Citations
117778
World Ranking
125
National Ranking
64

Medicine

D-Index
166
Citations
134292
World Ranking
600
National Ranking
348

Research.com Recognitions

  • 2026 - Research.com Genetics in United States Leader Award
  • 2025 - Research.com Genetics in United States Leader Award
  • 2024 - Research.com Genetics in United States Leader Award
  • 2023 - Research.com Genetics in United States Leader Award
  • 2001 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 1996 - Sedgwick Memorial Medal, American Public Health Association
  • 1996 - Potamkin Prize for Research in Pick's, Alzheimer's, and Related Diseases, American Academy of Neurology
  • 1995 - Metlife Foundation Award for Medical Research in Alzheimer's Disease

Overview

Rudolph E. Tanzi is affiliated with Harvard University in the United States. Their research spans several interconnected fields, including Medicine, Biochemistry, Genetics and Molecular Biology, and Neuroscience. Within these fields, their work addresses specialized subfields such as Physiology, Molecular Biology, Neurology, Cellular and Molecular Neuroscience, and Genetics.

The scientist's research focus includes a range of topics, most prominently in Alzheimer's disease research and treatments. Additional topics covered in their work include neuroinflammation and neurodegeneration mechanisms, cholinesterase and neurodegenerative diseases, tryptophan and brain disorders, genetic associations and epidemiology, dementia and cognitive impairment research, as well as bioinformatics and genomic networks.

Their recent papers demonstrate a wide scope of interests:

  • Trial of Sodium Phenylbutyrate-Taurursodiol for Amyotrophic Lateral Sclerosis, 2020, New England Journal of Medicine
  • Tau molecular diversity contributes to clinical heterogeneity in Alzheimer's disease, 2020, Nature Medicine
  • Exercise hormone irisin is a critical regulator of cognitive function, 2021, Nature Metabolism
  • Astrocytic interleukin-3 programs microglia and limits Alzheimer's disease, 2021, Nature
  • SARS-CoV-2 reservoir in post-acute sequelae of COVID-19 (PASC), 2023, Nature Immunology

Frequent co-authors collaborating with Rudolph E. Tanzi include:

  • Can Zhang (45 publications)
  • Dmitry Prokopenko (41 publications)
  • Se Hoon Choi (23 publications)
  • Christoph Lange (22 publications)
  • Kristina Mullin (21 publications)

Publication venues where this scientist frequently contributes include:

  • Alzheimer s & Dementia (28 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (22 publications)
  • Scientific Reports (8 publications)
  • Stroke (6 publications)
  • The Journal of Experimental Medicine (5 publications)

Rudolph E. Tanzi has received several awards recognizing their research:

  • Fellow of the American Association for the Advancement of Science (AAAS), 2001
  • Sedgwick Memorial Medal, American Public Health Association, 1996
  • Potamkin Prize for Research in Pick's, Alzheimer's, and Related Diseases, American Academy of Neurology, 1996
  • Metlife Foundation Award for Medical Research in Alzheimer's Disease, 1995

Best Publications

  • Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

    R. Sherrington;E. I. Rogaev;Y. Liang;E. A. Rogaeva

  • Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease.

    D. Scheuner;C. Eckman;C. Eckman;M. Jensen;X. Song

  • Candidate gene for the chromosome 1 familial Alzheimer's disease locus

    Ephrat Levy-Lahad;Wilma Wasco;Parvoneh Poorkaj;Donna M. Romano

  • A polymorphic DNA marker genetically linked to Huntington's disease

    James F. Gusella;Nancy S. Wexler;P. Michael Conneally;Susan L. Naylor

  • Twenty years of the Alzheimer's disease amyloid hypothesis: a genetic perspective.

    Rudolph E. Tanzi;Lars Bertram

  • Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.

    Adam C. Naj;Gyungah Jun;Gary W. Beecham;Li-San Wang

  • Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database

    Lars Bertram;Matthew B McQueen;Matthew B McQueen;Kristina Mullin;Deborah Blacker

  • Amyloid beta protein gene: cDNA, mRNA distribution, and genetic linkage near the Alzheimer locus

    R. E. Tanzi;J. F. Gusella;P. C. Watkins;G. A. P. Bruns

  • Association between Microdeletion and Microduplication at 16p11.2 and Autism

    Lauren A. Weiss;Yiping Shen;Joshua M. Korn;Joshua M. Korn;Dan E. Arking

  • Rapid induction of Alzheimer A beta amyloid formation by zinc.

    Ashley I. Bush;Warren H. Pettingell;Gerd Multhaup;Marc D. Paradis

  • Treatment with a Copper-Zinc Chelator Markedly and Rapidly Inhibits β-Amyloid Accumulation in Alzheimer's Disease Transgenic Mice

    Robert A Cherny;Craig S Atwood;Michel E Xilinas;Danielle N Gray

  • Insulin-degrading enzyme regulates the levels of insulin, amyloid β-protein, and the β-amyloid precursor protein intracellular domain in vivo

    Wesley Farris;Stefan Mansourian;Yang Chang;Loren Lindsley

  • The Wilson disease gene is a copper transporting ATPase with homology to the Menkes disease gene.

    R E Tanzi;K Petrukhin;I Chernov;J L Pellequer

  • Mapping autism risk loci using genetic linkage and chromosomal rearrangements

    Peter Szatmari;Andrew D. Paterson;Lonnie Zwaigenbaum;Wendy Roberts

  • The genetic defect causing familial Alzheimer's disease maps on chromosome 21

    Peter H. St George-Hyslop;Rudolph E. Tanzi;Ronald J. Polinsky;Jonathan L. Haines

  • Protease inhibitor domain encoded by an amyloid protein precursor mRNA associated with Alzheimer's disease.

    Rudolph E. Tanzi;Andrea I. McClatchey;Edward D. Lamperti;Edward D. Lamperti;Edward D. Lamperti;Lydia Villa-Komaroff;Lydia Villa-Komaroff

  • The Aβ Peptide of Alzheimer's Disease Directly Produces Hydrogen Peroxide through Metal Ion Reduction†

    Xudong Huang;Craig S. Atwood;Mariana A. Hartshorn;Gerd Multhaup

  • A three-dimensional human neural cell culture model of Alzheimer’s disease

    Se Hoon Choi;Young Hye Kim;Matthias Hebisch;Christopher Sliwinski

  • Systematic meta-analyses and field synopsis of genetic association studies in schizophrenia: the SzGene database.

    Nicole C Allen;Sachin Bagade;Matthew B McQueen;John P A Ioannidis;John P A Ioannidis;John P A Ioannidis

  • Dramatic aggregation of Alzheimer abeta by Cu(II) is induced by conditions representing physiological acidosis.

    C. S. Atwood;R. D. Moir;Xudong Huang;R. C. Scarpa

Frequent Co-Authors

Lars Bertram
Lars Bertram University of Lübeck
Robert D. Moir
Robert D. Moir Harvard University
Ashley I. Bush
Ashley I. Bush Florey Institute of Neuroscience and Mental Health
James F. Gusella
James F. Gusella Harvard University
Deborah Blacker
Deborah Blacker Harvard University
Bradley T. Hyman
Bradley T. Hyman Harvard University
Xudong Huang
Xudong Huang Harvard University
Robert A. Cherny
Robert A. Cherny Florey Institute of Neuroscience and Mental Health
Marilyn S. Albert
Marilyn S. Albert Johns Hopkins University School of Medicine
Mikko Hiltunen
Mikko Hiltunen University of Eastern Finland

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