2026 Dennis J. Selkoe: Medicine Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Best Scientists	203	250	235	165	154	736	238016
Medicine	206	142	130	97	88	721	243617

Research.com Recognitions

2026 - Research.com Medicine in United States Leader Award
2025 - Research.com Best Scientists Award
2025 - Research.com Medicine in United States Leader Award
2023 - Research.com Biology and Biochemistry in United States Leader Award
2005 - Member of the National Academy of Medicine (NAM)
2003 - Fellow of the American Association for the Advancement of Science (AAAS)
1989 - Sedgwick Memorial Medal, American Public Health Association
1989 - Potamkin Prize for Research in Pick's, Alzheimer's, and Related Diseases, American Academy of Neurology
1986 - Metlife Foundation Award for Medical Research in Alzheimer's Disease
Member of the Association of American Physicians
Member of the Association of American Physicians
Member of the Association of American Physicians

Overview

Dennis J. Selkoe is affiliated with Brigham and Women's Hospital in the United States. Their research primarily spans the field of medicine, with significant contributions to physiology, neurology, molecular biology, psychiatry and mental health, and cellular and molecular neuroscience.

The main research topics addressed by Selkoe include:

Alzheimer's disease research and treatments
Parkinson's Disease Mechanisms and Treatments
Dementia and Cognitive Impairment Research
Neuroscience and Neuropharmacology Research
Cholinesterase and Neurodegenerative Diseases
Neuroinflammation and Neurodegeneration Mechanisms
Cellular transport and secretion

Selkoe has published extensively in several notable scientific journals. The most frequent publication venues include:

Alzheimer's & Dementia
bioRxiv (Cold Spring Harbor Laboratory)
npj Parkinson's Disease
JAMA Neurology
The Journal of Prevention of Alzheimer's Disease

Some recent papers from their work are:

"A mechanistic hypothesis for the impairment of synaptic plasticity by soluble Aβ oligomers from Alzheimer's brain," 2020, Journal of Neurochemistry
"Parkinson's disease: proteinopathy or lipidopathy?", 2020, npj Parkinson's Disease
"Evaluating the Safety and Efficacy of Crenezumab vs Placebo in Adults With Early Alzheimer Disease," 2022, JAMA Neurology
"Aducanumab: Appropriate Use Recommendations Update," 2022, The Journal of Prevention of Alzheimer's Disease
"Stem cell-derived neurons reflect features of protein networks, neuropathology, and cognitive outcome of their aged human donors," 2021, Neuron

Frequent co-authors collaborating with Selkoe include:

Lei Liu
Jasmeer P. Chhatwal
Ulf Dettmer
Hyun-Sik Yang
Silke Nuber

Over the course of their career, Selkoe has received various awards, including:

Member of the National Academy of Medicine (NAM), 2005
Fellow of the American Association for the Advancement of Science (AAAS), 2003
Potamkin Prize for Research in Pick's, Alzheimer's, and Related Diseases, American Academy of Neurology, 1989
Sedgwick Memorial Medal, American Public Health Association, 1989
Metlife Foundation Award for Medical Research in Alzheimer's Disease, 1986
Member of the Association of American Physicians

Best Publications

The Amyloid Hypothesis of Alzheimer's Disease: Progress and Problems on the Road to Therapeutics

John Hardy;Dennis J. Selkoe

16561
Citations
Alzheimer's Disease: Genes, Proteins, and Therapy

Dennis J. Selkoe

9655
Citations
Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide.

Christian Haass;Dennis J. Selkoe

6812
Citations
The amyloid hypothesis of Alzheimer's disease at 25 years

Dennis J Selkoe;John Hardy

6410
Citations
Alzheimer's Disease Is a Synaptic Failure

Dennis J. Selkoe

6130
Citations
Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory.

Ganesh M Shankar;Shaomin Li;Tapan H Mehta;Amaya Garcia-Munoz

4513
Citations
Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease.

D. Scheuner;C. Eckman;C. Eckman;M. Jensen;X. Song

4221
Citations
The molecular pathology of Alzheimer's disease.

Dennis J. Selkoe

4002
Citations
Advancing research diagnostic criteria for Alzheimer's disease: the IWG-2 criteria

Bruno Dubois;Bruno Dubois;Howard H Feldman;Claudia Jacova;Harald Hampel;Harald Hampel

3702
Citations
Complement and microglia mediate early synapse loss in Alzheimer mouse models

Soyon Hong;Victoria F. Beja-Glasser;Bianca M. Nfonoyim;Arnaud Frouin

3297
Citations
A beta oligomers - a decade of discovery.

Dominic M. Walsh;Dennis J. Selkoe

2832
Citations
Mutation of the β-amyloid precursor protein in familial Alzheimer's disease increases β-protein production

Martin Citron;Tilman Oltersdorf;Christian Haass;Lisa McConlogue

2528
Citations
Translating cell biology into therapeutic advances in Alzheimer's disease

Dennis J. Selkoe

2382
Citations
Isolation and quantification of soluble Alzheimer's β-peptide from biological fluids

Peter Seubert;Carmen Vigo-Pelfrey;Fred Esch;Michael Lee

2333
Citations
Natural oligomers of the amyloid-|[beta]| protein specifically disrupt cognitive function

James P Cleary;Dominic M Walsh;Dominic M Walsh;Jacki J Hofmeister;Ganesh M Shankar

2190
Citations
Folding proteins in fatal ways

Dennis J. Selkoe

2055
Citations
Natural Oligomers of the Alzheimer Amyloid-β Protein Induce Reversible Synapse Loss by Modulating an NMDA-Type Glutamate Receptor-Dependent Signaling Pathway

Ganesh M. Shankar;Brenda L. Bloodgood;Matthew Townsend;Dominic M. Walsh

2047
Citations
Microtubule-associated protein tau (tau) is a major antigenic component of paired helical filaments in Alzheimer disease

Kenneth S. Kosik;Catharine L. Joachim;Dennis J. Selkoe

1849
Citations
Insulin-degrading enzyme regulates the levels of insulin, amyloid β-protein, and the β-amyloid precursor protein intracellular domain in vivo

Wesley Farris;Stefan Mansourian;Yang Chang;Loren Lindsley

1836
Citations
Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid β-protein in both transfected cells and transgenic mice

Martin Citron;David Westaway;Weiming Xia;George Carlson

1800
Citations

Frequent Co-Authors

Dominic M. Walsh Brigham and Women's Hospital

Michael S. Wolfe University of Kansas

Kenneth S. Kosik University of California, Santa Barbara

Christian Haass Ludwig-Maximilians-Universität München

Weiming Xia United States Department of Veterans Affairs

Martin Citron Amgen (United States)

David B. Teplow University of California, Los Angeles

Carmela R. Abraham Boston University

Reisa A. Sperling Brigham and Women's Hospital

Bradley T. Hyman Harvard University

External Links

Wikipedia of Dennis J. Selkoe Personal website of Dennis J. Selkoe

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