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Medicine

D-Index
90
Citations
34271
World Ranking
12105
National Ranking
6212

Overview

Ronald L. Hamilton is affiliated with the University of Pittsburgh in the United States. Their research spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, focusing particularly on Molecular Biology, Genetics, Physiology, Pulmonary and Respiratory Medicine, and Psychiatry and Mental Health as subfields.

Hamilton's scientific work covers several main topics including Alzheimer's disease research and treatments, Hedgehog signaling pathway studies, chromatin remodeling and cancer, genomics and chromatin dynamics, glioma diagnosis and treatment, brain metastases and treatment, and melanoma and MAPK pathways.

They have contributed to multiple publications, with recent papers including:

  • Exceptionally low likelihood of Alzheimer's dementia in APOE2 homozygotes from a 5,000-person neuropathological study (2020, Nature Communications)
  • The transcriptional landscape of Shh medulloblastoma (2021, Nature Communications)
  • Pattern of Relapse and Treatment Response in WNT-Activated Medulloblastoma (2020, Cell Reports Medicine)
  • Manifestations of Alzheimer's disease genetic risk in the blood are evident in a multiomic analysis in healthy adults aged 18 to 90 (2022, Scientific Reports)
  • LATE-NC risk alleles (in TMEM106B, GRN, and ABCC9 genes) among persons with African ancestry (2023, Journal of Neuropathology & Experimental Neurology)

Frequent coauthors of Hamilton include:

  • Nilüfer Ertekin-Taner
  • David W. Fardo
  • Wiesława Grajkowska
  • Ian F. Pollack
  • Vijay Ramaswamy

Hamilton's research is often published in venues such as UNC Libraries, Nature Communications, Cell Reports Medicine, Scientific Reports, and the Journal of Neuropathology & Experimental Neurology.

Best Publications

  • Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.

    Adam C. Naj;Gyungah Jun;Gary W. Beecham;Li-San Wang

  • Chronic traumatic encephalopathy in a National Football League player.

    Bennet I. Omalu;Steven T. DeKosky;Ryan L. Minster;M Ilyas Kamboh

  • Intertumoral Heterogeneity within Medulloblastoma Subgroups

    Florence M.G. Cavalli;Marc Remke;Marc Remke;Marc Remke;Ladislav Rampasek;John Peacock

  • Post-mortem Correlates of in Vivo PiB-PET Amyloid Imaging in a Typical Case of Alzheimer's Disease

    Milos D. Ikonomovic;William E. Klunk;Eric E. Abrahamson;Chester A. Mathis

  • Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

    Rebecca Sims;Sven J. Van Der Lee;Adam C. Naj;Céline Bellenguez;Céline Bellenguez

  • Expression of Nrf2 in Neurodegenerative Diseases

    Chenere P. Ramsey;Charles A. Glass;Marshall B. Montgomery;Kathryn A. Lindl

  • Induction of CD8+ T-cell responses against novel glioma-associated antigen peptides and clinical activity by vaccinations with {alpha}-type 1 polarized dendritic cells and polyinosinic-polycytidylic acid stabilized by lysine and carboxymethylcellulose in patients with recurrent malignant glioma.

    Hideho Okada;Pawel Kalinski;Ryo Ueda;Aki Hoji

  • Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions

    Vivianna M. Van Deerlin;Patrick M A Sleiman;Maria Martinez-Lage;Maria Martinez-Lage;Alice Chen-Plotkin

  • Co-morbidity of TDP-43 proteinopathy in Lewy body related diseases.

    Hanae Nakashima-Yasuda;Kunihiro Uryu;John Robinson;Sharon X. Xie

  • Multiple recurrent genetic events converge on control of histone lysine methylation in medulloblastoma

    Paul A. Northcott;Yukiko Nakahara;Xiaochong Wu;Lars Feuk

  • Emerging histomorphologic phenotypes of chronic traumatic encephalopathy in American athletes.

    Bennet Omalu;Bennet Omalu;Julian Bailes;Ronald L Hamilton;Ronald L Hamilton;M Ilyas Kamboh;M Ilyas Kamboh

  • APOE ε4 increases risk for dementia in pure synucleinopathies.

    Debby Tsuang;James B. Leverenz;Oscar L. Lopez;Ronald L. Hamilton

  • COX-2 Blockade Suppresses Gliomagenesis by Inhibiting Myeloid-Derived Suppressor Cells

    Mitsugu Fujita;Gary Kohanbash;Wendy Fellows-Mayle;Ronald L. Hamilton

  • Temozolomide in the treatment of high-grade gliomas in children: a report from the Children's Oncology Group

    Kenneth J. Cohen;Ian F. Pollack;Tianni Zhou;Allen Buxton

  • Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis

    David C. Whitcomb;Jessica LaRusch;Alyssa M. Krasinskas;Lambertus Klei

  • Divergent clonal selection dominates medulloblastoma at recurrence

    A. Sorana Morrissy;Livia Garzia;David J.H. Shih;Scott Zuyderduyn

  • Prognostic value of medulloblastoma extent of resection after accounting for molecular subgroup: a retrospective integrated clinical and molecular analysis

    Eric M. Thompson;Eric M. Thompson;Thomas Hielscher;Eric Bouffet;Marc Remke

  • The Binding of 2-(4′-Methylaminophenyl)Benzothiazole to Postmortem Brain Homogenates Is Dominated by the Amyloid Component

    William E. Klunk;Yanming Wang;Guo feng Huang;Manik L. Debnath

  • Brain membrane phospholipid alterations in Alzheimer's disease.

    Jay W. Pettegrew;Kanagasabai Panchalingam;Ronald L. Hamilton;Richard J. McClure

  • Increases in Bcl-2 and cleavage of caspase-1 and caspase-3 in human brain after head injury

    R. S. B. Clark;P. M. Kochanek;Minzhi Chen;S. C. Watkins

Frequent Co-Authors

Ian F. Pollack
Ian F. Pollack University of Pittsburgh
Steven T. DeKosky
Steven T. DeKosky University of Florida
Oscar L. Lopez
Oscar L. Lopez University of Pittsburgh
Hideho Okada
Hideho Okada University of California, San Francisco
William E. Klunk
William E. Klunk University of Pittsburgh
Milos D. Ikonomovic
Milos D. Ikonomovic University of Pittsburgh
Chester A. Mathis
Chester A. Mathis University of Pittsburgh
Marina N. Nikiforova
Marina N. Nikiforova University of Pittsburgh
Craig Horbinski
Craig Horbinski Northwestern University
Jeffrey Kaye
Jeffrey Kaye Oregon Health & Science University

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