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Medicine

D-Index
111
Citations
55471
World Ranking
5266
National Ranking
2841

Overview

Chester A. Mathis is affiliated with the University of Pittsburgh in the United States. Their research primarily centers on medicine, with a significant focus on psychiatry and mental health, physiology, radiology, nuclear medicine and imaging, cognitive neuroscience, and neurology.

The scientist's research encompasses several main topics, including:

  • Dementia and Cognitive Impairment Research
  • Alzheimer's disease research and treatments
  • Functional Brain Connectivity Studies
  • Down syndrome and intellectual disability research
  • Medical Imaging Techniques and Applications
  • Advanced Neuroimaging Techniques and Applications
  • Frailty in Older Adults

Their recent publications include the following papers:

  • "Spread of pathological tau proteins through communicating neurons in human Alzheimer's disease," 2020, Nature Communications
  • "Functional brain architecture is associated with the rate of tau accumulation in Alzheimer's disease," 2020, Nature Communications
  • "In vivo staging of regional amyloid deposition," 2022, Columbia Academic Commons (Columbia University)
  • "Longitudinal Associations of Blood Phosphorylated Tau181 and Neurofilament Light Chain With Neurodegeneration in Alzheimer Disease," 2021, JAMA Neurology
  • "Characterizing Heterogeneity in Neuroimaging, Cognition, Clinical Symptoms, and Genetics Among Patients With Late-Life Depression," 2022, JAMA Psychiatry

Chester A. Mathis has frequently collaborated with several co-authors, including:

  • John C. Morris
  • Michael Donohue
  • Andrew J. Saykin
  • Laurel Beckett
  • Karen Crawford

The scientist has published extensively in certain venues, with the most frequent being:

  • Alzheimer s & Dementia
  • Nature Communications
  • Scientific Reports
  • GeroScience
  • Nuclear Medicine and Biology

Best Publications

  • Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound-B.

    William E. Klunk;Henry Engler;Agneta Nordberg;Yanming Wang

  • Molecular, Structural, and Functional Characterization of Alzheimer's Disease: Evidence for a Relationship between Default Activity, Amyloid, and Memory

    Randy L. Buckner;Abraham Z. Snyder;Benjamin J. Shannon;Gina LaRossa

  • Inverse relation between in vivo amyloid imaging load and cerebrospinal fluid Abeta42 in humans.

    Anne M. Fagan;Mark A. Mintun;Robert H. Mach;Sang-Yoon Lee

  • Frequent Amyloid Deposition Without Significant Cognitive Impairment Among the Elderly

    Howard Jay Aizenstein;Robert D. Nebes;Judith A. Saxton;Julie C. Price

  • [11C]PIB in a nondemented population: potential antecedent marker of Alzheimer disease.

    M. A. Mintun;G. N. LaRossa;Y. I. Sheline;C. S. Dence

  • The Centiloid Project: Standardizing quantitative amyloid plaque estimation by PET

    William E. Klunk;William E. Klunk;Robert A. Koeppe;Julie C. Price;Tammie L. Benzinger;Tammie L. Benzinger

  • Early role of vascular dysregulation on late-onset Alzheimer’s disease based on multifactorial data-driven analysis

    Y. Iturria-Medina;R. C. Sotero;P. J. Toussaint;J. M. Mateos-Pérez

  • SYNTHESIS AND EVALUATION OF 11C-LABELED 6-SUBSTITUTED 2-ARYLBENZOTHIAZOLES AS AMYLOID IMAGING AGENTS

    Chester A. Mathis;Yanming Wang;Daniel P. Holt;Guo Feng Huang

  • Post-mortem Correlates of in Vivo PiB-PET Amyloid Imaging in a Typical Case of Alzheimer's Disease

    Milos D. Ikonomovic;William E. Klunk;Eric E. Abrahamson;Chester A. Mathis

  • 11C PiB and structural MRI provide complementary information in imaging of Alzheimer's disease and amnestic mild cognitive impairment.

    Clifford R. Jack;Val J. Lowe;Matthew L. Senjem;Stephen D. Weigand

  • C-11-PiB PET assessment of change in fibrillar amyloid-beta load in patients with Alzheimer's disease treated with bapineuzumab: a phase 2, double-blind, placebo-controlled, ascending-dose study

    Juha O Rinne;David J Brooks;Martin N Rossor;Nick C Fox

  • Longitudinal Assessment of Aβ and Cognition in Aging and Alzheimer Disease

    Victor L Villemagne;Kerryn E Pike;Gaël Chételat;Kathryn A Ellis

  • Fibrillar amyloid-β burden in cognitively normal people at 3 levels of genetic risk for Alzheimer's disease

    Eric M. Reiman;Kewei Chen;Xiaofen Liu;Daniel Bandy

  • Beta-amyloid imaging and memory in non-demented individuals: evidence for preclinical Alzheimer's disease.

    Kerryn Elizabeth Pike;Gregory Raymond Savage;Victor L Villemagne;Steven Ng

  • Amphetamine-induced dopamine release in human ventral striatum correlates with euphoria

    Wayne C. Drevets;Clara H. Gautier;Julie C Price;David J. Kupfer

  • PET imaging of serotonin 1A receptor binding in depression

    Wayne C Drevets;Ellen Frank;Julie C Price;David J Kupfer

  • Kinetic Modeling of Amyloid Binding in Humans using PET Imaging and Pittsburgh Compound-B:

    Julie C Price;William E Klunk;Brian J Lopresti;Xueling Lu

  • Cortical cholinergic function is more severely affected in parkinsonian dementia than in Alzheimer disease: an in vivo positron emission tomographic study.

    Nicolaas I. Bohnen;Daniel I. Kaufer;Larry S. Ivanco;Brian Lopresti

  • Simplified quantification of Pittsburgh Compound B amyloid imaging PET studies: a comparative analysis.

    Brian J. Lopresti;William E. Klunk;Chester A. Mathis;Jessica A. Hoge

  • Uncharged thioflavin-T derivatives bind to amyloid-beta protein with high affinity and readily enter the brain.

    William E. Klunk;Yanming Wang;Guo feng Huang;Manik L. Debnath

Frequent Co-Authors

William E. Klunk
William E. Klunk University of Pittsburgh
Julie C. Price
Julie C. Price Harvard University
Steven T. DeKosky
Steven T. DeKosky University of Florida
Beth E. Snitz
Beth E. Snitz University of Pittsburgh
Oscar L. Lopez
Oscar L. Lopez University of Pittsburgh
Howard J. Aizenstein
Howard J. Aizenstein University of Pittsburgh
Milos D. Ikonomovic
Milos D. Ikonomovic University of Pittsburgh
Carolyn C. Meltzer
Carolyn C. Meltzer Emory University
William J. Jagust
William J. Jagust University of California, Berkeley
Judith Saxton
Judith Saxton University of Pittsburgh

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