World's Best Scientists 2026 revealed!
Patrice Courvalin

Patrice Courvalin

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Genetics
France
2026
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Microbiology
France
2026

D-Index & Metrics

Microbiology

D-Index
132
Citations
57707
World Ranking
75
National Ranking
5

Genetics

D-Index
128
Citations
44717
World Ranking
279
National Ranking
5

Research.com Recognitions

  • 2026 - Research.com Genetics in France Leader Award
  • 2026 - Research.com Microbiology in France Leader Award
  • 2025 - Research.com Genetics in France Leader Award
  • 2025 - Research.com Microbiology in France Leader Award
  • 2024 - Research.com Genetics in France Leader Award
  • 2024 - Research.com Genetics and Molecular Biology in France Leader Award
  • 2017 - Member of Academia Europaea
  • 2012 - ASM Award for Research in Clinical Microbiology, American Society for Microbiology

Overview

Patrice Courvalin is affiliated with the Institut Pasteur in France and has contributed extensively to the study of antibiotic resistance and related fields. Their research encompasses multiple aspects of microbiology, biochemistry, and medicine, with a focus on molecular mechanisms underlying resistance, efficacy of antibiotics, and infection control.

Their recent publications include:

  • Antibiotic resistance: turning evolutionary principles into clinical reality, 2020, FEMS Microbiology Reviews
  • Reducing antibiotic prescribing and addressing the global problem of antibiotic resistance by targeted hygiene in the home and everyday life settings: A position paper, 2020, American Journal of Infection Control
  • Co-occurrence of aminoglycoside and β-lactam resistance mechanisms in aminoglycoside-non-susceptible Escherichia coli isolated in the Zurich area, Switzerland, 2020, International Journal of Antimicrobial Agents
  • Improvement of a disk diffusion method for antibiotic susceptibility testing of anaerobic bacteria. French recommendations revisited for 2020, 2020, Anaerobe
  • Evaluation of standardized automated rapid antimicrobial susceptibility testing of Enterobacterales-containing blood cultures: a proof-of-principle study, 2020, Journal of Antimicrobial Chemotherapy

The scientist frequently collaborates with:

  • Elias Bodendoerfer
  • Erik C. Böttger
  • Stefano Mancini
  • Sebastian Herren
  • Kim Röthlin

Major publication venues include:

  • Journal of Antimicrobial Chemotherapy
  • FEMS Microbiology Reviews
  • American Journal of Infection Control
  • International Journal of Antimicrobial Agents
  • Anaerobe

Patrice Courvalin's work spans several main fields of study:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Within these broader fields, their subfields of focus comprise:

  • Molecular Medicine
  • Pharmacology
  • Infectious Diseases
  • Clinical Biochemistry
  • Applied Microbiology and Biotechnology

Central topics in their research include:

  • Antibiotic Resistance in Bacteria
  • Antibiotics Pharmacokinetics and Efficacy
  • Bacterial Identification and Susceptibility Testing
  • Antibiotic Use and Resistance
  • Clostridium difficile and Clostridium perfringens research
  • Infection Control in Healthcare
  • Pharmaceutical and Antibiotic Environmental Impacts

They were recognized by election as a Member of Academia Europaea in 2017 and received the ASM Award for Research in Clinical Microbiology from the American Society for Microbiology in 2012.

Best Publications

  • Plasmid-mediated resistance to vancomycin and teicoplanin in Enterococcus faecium.

    Roland Leclercq;Eliane Derlot;Jean Duval;Patrice Courvalin

  • Tackling antibiotic resistance

    Karen Bush;Patrice Courvalin;Gautam Dantas;Julian Davies

  • Nomenclature for macrolide and macrolide-lincosamide-streptogramin B resistance determinants.

    Marilyn C Roberts;Joyce Sutcliffe;Patrice Courvalin;Lars Bogo Jensen

  • Detection of glycopeptide resistance genotypes and identification to the species level of clinically relevant enterococci by PCR

    Unknown

  • Vancomycin resistance in gram-positive cocci.

    Unknown

  • Genetics and mechanisms of glycopeptide resistance in enterococci.

    M Arthur;P Courvalin

  • Bacterial resistance to macrolide, lincosamide, and streptogramin antibiotics by target modification.

    R Leclercq;P Courvalin

  • Molecular basis for vancomycin resistance in Enterococcus faecium BM4147: biosynthesis of a depsipeptide peptidoglycan precursor by vancomycin resistance proteins VanH and VanA.

    Timothy D. H. Bugg;Gerard D. Wright;Sylvie Dutka-Malen;Michel Arthur

  • Resistance-Nodulation-Cell Division-Type Efflux Pump Involved in Aminoglycoside Resistance in Acinetobacter baumannii Strain BM4454

    Sophie Magnet;Patrice Courvalin;Thierry Lambert

  • Multidrug resistance in Yersinia pestis mediated by a transferable plasmid

    Marc Galimand;Annie Guiyoule;Guy Gerbaud;Bruno Rasoamanana

  • Detection of glycopeptide resistance genotypes and identification to the species level of clinically relevant enterococci by PCR

    Unknown

  • Efflux-Mediated Antibiotic Resistance in Acinetobacter spp.

    Sébastien Coyne;Patrice Courvalin;Bruno Périchon

  • Characterization of Tn1546, a Tn3-related transposon conferring glycopeptide resistance by synthesis of depsipeptide peptidoglycan precursors in Enterococcus faecium BM4147

    Unknown

  • Global distribution of Panton-Valentine leukocidin--positive methicillin-resistant Staphylococcus aureus, 2006.

    Anne Tristan;Michele Bes;Helene Meugnier;Gerard Lina

  • Nucleotide sequence of the Streptococcus faecalis plasmid gene encoding the 3'5"-aminoglycoside phosphotransferase type III.

    Patrick Trieu-Cuot;Patrice Courvalin

  • Expression of the RND-Type Efflux Pump AdeABC in Acinetobacter baumannii Is Regulated by the AdeRS Two-Component System

    Isabelle Marchand;Laurence Damier-Piolle;Patrice Courvalin;Thierry Lambert

  • Transferable resistance to third-generation cephalosporins in clinical isolates of Klebsiella pneumoniae: identification of CTX-1, a novel β-lactamase

    D. Sirot;J. Sirot;R. Labia;A. Morand

  • Modes and Modulations of Antibiotic Resistance Gene Expression

    Florence Depardieu;Isabelle Podglajen;Roland Leclercq;Ekkehard Collatz

  • AdeIJK, a Resistance-Nodulation-Cell Division Pump Effluxing Multiple Antibiotics in Acinetobacter baumannii

    Laurence Damier-Piolle;Sophie Magnet;Sylvie Brémont;Thierry Lambert

  • The VanS-VanR two-component regulatory system controls synthesis of depsipeptide peptidoglycan precursors in Enterococcus faecium BM4147

    M Arthur;C Molinas;P Courvalin

  • Plasmid-mediated high-level resistance to aminoglycosides in Enterobacteriaceae due to 16S rRNA methylation

    Marc Galimand;Patrice Courvalin;Thierry Lambert

  • Transfer of antibiotic resistance genes between gram-positive and gram-negative bacteria.

    P Courvalin

  • Antibiotic resistance in Listeria spp.

    Emmanuelle Charpentier;Patrice Courvalin

  • VanA-Type Vancomycin-Resistant Staphylococcus aureus

    Bruno Périchon;Patrice Courvalin

Frequent Co-Authors

Michel Arthur
Michel Arthur Centre de Recherche des Cordeliers
Patrick Trieu-Cuot
Patrick Trieu-Cuot Institut Pasteur
Antoine Andremont
Antoine Andremont Université Paris Cité
Erik C. Böttger
Erik C. Böttger University of Zurich
Alexei Savchenko
Alexei Savchenko University of Calgary
Wladimir Sougakoff
Wladimir Sougakoff Sorbonne University
Vincent Jarlier
Vincent Jarlier Sorbonne University
Roland Leclercq
Roland Leclercq Université Paris Cité
Guillaume Arlet
Guillaume Arlet Sorbonne University
Julian Davies
Julian Davies University of British Columbia

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