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Microbiology

D-Index
71
Citations
16185
World Ranking
1869
National Ranking
106

Overview

Michel Arthur is affiliated with the Centre de Recherche des Cordeliers in France. Their research spans biochemistry, genetics, and molecular biology, with significant focus on medicine. The scientist's work is concentrated in subfields including molecular biology, molecular medicine, genetics, infectious diseases, and organic chemistry.

The research topics they have extensively explored include antibiotic resistance in bacteria, bacterial genetics and biotechnology, RNA and protein synthesis mechanisms, antimicrobial resistance in Staphylococcus, antibiotics pharmacokinetics and efficacy, click chemistry and applications, and tuberculosis research and epidemiology.

Their recent published papers include:

  • Molecular basis of β-lactam antibiotic resistance of ESKAPE bacterium E. faecium Penicillin Binding Protein PBP5, 2023, Nature Communications
  • Role of endopeptidases in peptidoglycan synthesis mediated by alternative cross-linking enzymes in Escherichia coli, 2021, The EMBO Journal
  • Genome-wide identification of genes required for alternative peptidoglycan cross-linking in Escherichia coli revealed unexpected impacts of β-lactams, 2022, Nature Communications
  • Heavy isotope labeling and mass spectrometry reveal unexpected remodeling of bacterial cell wall expansion in response to drugs, 2022, eLife
  • Diazabicyclooctane Functionalization for Inhibition of β-Lactamases from Enterobacteria, 2020, Journal of Medicinal Chemistry

Frequent co-authors collaborating with Michel Arthur are:

  • Jean-Emmanuel Hugonnet
  • Filippo Rusconi
  • Mélanie Ethève-Quelquejeu
  • Laura Iannazzo
  • Yucheng Liang

The scientist's publications most frequently appear in the following venues:

  • Nature Communications
  • Antimicrobial Agents and Chemotherapy
  • Chemistry - A European Journal
  • bioRxiv (Cold Spring Harbor Laboratory)
  • eLife

Best Publications

  • Genetics and mechanisms of glycopeptide resistance in enterococci.

    M Arthur;P Courvalin

  • Molecular basis for vancomycin resistance in Enterococcus faecium BM4147: biosynthesis of a depsipeptide peptidoglycan precursor by vancomycin resistance proteins VanH and VanA.

    Timothy D. H. Bugg;Gerard D. Wright;Sylvie Dutka-Malen;Michel Arthur

  • Characterization of Tn1546, a Tn3-related transposon conferring glycopeptide resistance by synthesis of depsipeptide peptidoglycan precursors in Enterococcus faecium BM4147

    Unknown

  • Glycopeptide resistance in enterococci

    Michel Arthur;Peter Reynolds;Patrice Courvalin

  • The Peptidoglycan of Stationary-Phase Mycobacterium tuberculosis Predominantly Contains Cross-Links Generated by l,d-Transpeptidation

    Marie Lavollay;Michel Arthur;Michel Arthur;Michel Arthur;Martine Fourgeaud;Martine Fourgeaud;Martine Fourgeaud;Lionel Dubost

  • The VanS-VanR two-component regulatory system controls synthesis of depsipeptide peptidoglycan precursors in Enterococcus faecium BM4147

    M Arthur;C Molinas;P Courvalin

  • Resolution of Recent Evolutionary Divergence among Escherichia coli from Related Lineages: The Application of Pulsed Field Electrophoresis to Molecular Epidemiology

    Robert D. Arbeit;Michel Arthur;Roberta Dunn;Cheung Kim

  • The Mycobacterium tuberculosis protein LdtMt2 is a nonclassical transpeptidase required for virulence and resistance to amoxicillin

    Radhika Gupta;Marie Lavollay;Marie Lavollay;Marie Lavollay;Jean Luc Mainardi;Michel Arthur;Michel Arthur;Michel Arthur

  • A novel peptidoglycan cross-linking enzyme for a beta-lactam-resistant transpeptidation pathway

    Jean-Luc Mainardi;Jean-Luc Mainardi;Martine Fourgeaud;Jean-Emmanuel Hugonnet;Lionel Dubost

  • Glycopeptide resistance mediated by enterococcal transposon Tn1546 requires production of VanX for hydrolysis of D-alanyl-D-alanine

    Peter E. Reynolds;Florence Depardieu;Sylvie Dutka-Malen;Michel Arthur

  • Identification of the L,D-transpeptidases responsible for attachment of the Braun lipoprotein to Escherichia coli peptidoglycan.

    Sophie Magnet;Samuel Bellais;Samuel Bellais;Samuel Bellais;Lionel Dubost;Martine Fourgeaud;Martine Fourgeaud;Martine Fourgeaud

  • Molecular epidemiology of adhesin and hemolysin virulence factors among uropathogenic Escherichia coli.

    M. Arthur;C. E. Johnson;R. H. Rubin;R. D. Arbeit

  • Evolution of peptidoglycan biosynthesis under the selective pressure of antibiotics in Gram-positive bacteria

    Jean-Luc Mainardi;Régis Villet;Régis Villet;Régis Villet;Timothy D. Bugg;Claudine Mayer;Claudine Mayer;Claudine Mayer

  • Identification of the l,d-Transpeptidases for Peptidoglycan Cross-Linking in Escherichia coli

    Sophie Magnet;Sophie Magnet;Sophie Magnet;Lionel Dubost;Arul Marie;Michel Arthur;Michel Arthur;Michel Arthur

  • Covalent attachment of proteins to peptidoglycan.

    Shaynoor Dramsi;Shaynoor Dramsi;Sophie Magnet;Sophie Magnet;Sophie Magnet;Sophie Davison;Sophie Davison;Michel Arthur;Michel Arthur;Michel Arthur

  • Contribution of VanY D,D-carboxypeptidase to glycopeptide resistance in Enterococcus faecalis by hydrolysis of peptidoglycan precursors.

    M Arthur;F Depardieu;H A Snaith;P E Reynolds

  • THE VANA GLYCOPEPTIDE RESISTANCE PROTEIN IS RELATED TO D-ALANYL-D-ALANINE LIGASE CELL WALL BIOSYNTHESIS ENZYMES

    S Dutka-Malen;C Molinas;M Arthur;P Courvalin

  • Quantitative analysis of the metabolism of soluble cytoplasmic peptidoglycan precursors of glycopeptide‐resistant enterococci

    Michel Arthur;Florence Depardieu;Peter Reynolds;Patrice Courvalin

  • Glycopeptide resistance in enterococci.

    Unknown

  • In Vitro Cross-Linking of Mycobacterium tuberculosis Peptidoglycan by l,d-Transpeptidases and Inactivation of These Enzymes by Carbapenems

    Mathilde Cordillot;Mathilde Cordillot;Mathilde Cordillot;Vincent Dubée;Vincent Dubée;Vincent Dubée;Sébastien Triboulet;Sébastien Triboulet;Sébastien Triboulet;Lionel Dubost

  • Inactivation of Mycobacterium tuberculosis l,d-Transpeptidase LdtMt1 by Carbapenems and Cephalosporins

    Vincent Dubée;Vincent Dubée;Vincent Dubée;Sébastien Triboulet;Sébastien Triboulet;Sébastien Triboulet;Jean-Luc Mainardi;Mélanie Ethève-Quelquejeu

  • Novel Mechanism of β-Lactam Resistance Due to Bypass of DD-Transpeptidation in Enterococcus faecium

    Jean-Luc Mainardi;Raymond Legrand;Michel Arthur;Bernard Schoot

  • Origin and evolution of genes specifying resistance to macrolide, lincosamide and streptogramin antibiotics: data and hypotheses

    M Arthur;A Brisson-Noël;P Courvalin

Frequent Co-Authors

Jean-Luc Mainardi
Jean-Luc Mainardi Université Paris Cité
Patrice Courvalin
Patrice Courvalin Institut Pasteur
Laurent Gutmann
Laurent Gutmann Université Paris Cité
Dominique Mengin-Lecreulx
Dominique Mengin-Lecreulx University of Paris-Saclay
Didier Blanot
Didier Blanot University of Paris-Saclay
Louis B. Rice
Louis B. Rice Brown University
Herman van Tilbeurgh
Herman van Tilbeurgh University of Paris-Saclay
Jean-Louis Herrmann
Jean-Louis Herrmann Versailles Saint-Quentin-en-Yvelines University
Christiane Bouchier
Christiane Bouchier Institut Pasteur
Wladimir Sougakoff
Wladimir Sougakoff Sorbonne University

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