World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
85
Citations
26685
World Ranking
2661
National Ranking
921

Research.com Recognitions

  • 2007 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Shahriar Mobashery is affiliated with the University of Notre Dame in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with a specific focus on subfields including Molecular Biology, Infectious Diseases, Pharmacology, Molecular Medicine, and Organic Chemistry.

The scientist's main research topics include:

  • Antibiotic Resistance in Bacteria
  • Bacterial Genetics and Biotechnology
  • Clostridium difficile and Clostridium perfringens research
  • Antibiotics Pharmacokinetics and Efficacy
  • Antimicrobial Resistance in Staphylococcus
  • Bacterial biofilms and quorum sensing
  • Glycosylation and Glycoproteins Research

Shahriar Mobashery has contributed to several peer-reviewed publications, with selected recent papers being:

  • β-Lactams against the Fortress of the Gram-Positive Staphylococcus aureus Bacterium, 2020, Chemical Reviews
  • Exploration of the Structural Space in 4(3H)-Quinazolinone Antibacterials, 2020, Journal of Medicinal Chemistry
  • Unconventional Antibacterials and Adjuvants, 2021, Accounts of Chemical Research
  • An Atypical ABC Transporter Is Involved in Antifungal Resistance and Host Interactions in the Pathogenic Fungus Cryptococcus neoformans, 2022, mBio
  • A type VI secretion system delivers a cell wall amidase to target bacterial competitors, 2020, Molecular Microbiology

The scientist frequently collaborates with colleagues in various research projects. Their most frequent co-authors include:

  • Mayland Chang
  • Choon Kim
  • Jed F. Fisher
  • Mijoon Lee
  • Yuanyuan Qian

Mobashery's work is regularly published in several specialized venues, with multiple contributions to the following journals and platforms:

  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature
  • Journal of Medicinal Chemistry
  • ACS Pharmacology & Translational Science
  • Chemical Biology & Drug Design
  • Protein Science

In recognition of professional achievements, Shahriar Mobashery was named a Fellow of the American Association for the Advancement of Science (AAAS) in 2007.

Best Publications

  • Bacterial Resistance to β-Lactam Antibiotics: Compelling Opportunism, Compelling Opportunity†

    Jed F. Fisher;Samy O. Meroueh;Shahriar Mobashery

  • Aminoglycosides: perspectives on mechanisms of action and resistance and strategies to counter resistance.

    Lakshmi P. Kotra;Jalal Haddad;Shahriar Mobashery

  • Kinship and Diversification of Bacterial Penicillin-Binding Proteins and β-Lactamases

    Irina Massova;Shahriar Mobashery

  • A Highly Specific Inhibitor of Matrix Metalloproteinase-9 Rescues Laminin from Proteolysis and Neurons from Apoptosis in Transient Focal Cerebral Ischemia

    Zezong Gu;Jiankun Cui;Stephen Brown;Rafael Fridman

  • Three-dimensional structure of the bacterial cell wall peptidoglycan

    Samy O. Meroueh;Krisztina Z. Bencze;Dusan Hesek;Mijoon Lee

  • Activation of Progelatinase B (MMP-9) by Gelatinase A (MMP-2)

    Rafael Fridman;Marta Toth;Daniel Peña;Shahriar Mobashery

  • Kinetic analysis of the binding of human matrix metalloproteinase-2 and -9 to tissue inhibitor of metalloproteinase (TIMP)-1 and TIMP-2.

    Matthew W. Olson;David C. Gervasi;Shahriar Mobashery;Rafael Fridman

  • The Basis for Resistance to β-Lactam Antibiotics by Penicillin-binding Protein 2a of Methicillin-resistant Staphylococcus aureus

    Cosimo Fuda;Maxim Suvorov;Sergei B. Vakulenko;Shahriar Mobashery

  • Bacterial cell-wall recycling

    Jarrod W. Johnson;Jed F. Fisher;Shahriar Mobashery

  • Recent advances in MMP inhibitor design.

    Jed F. Fisher;Shahriar Mobashery

  • Penicillin-binding protein 2a of methicillin-resistant Staphylococcus aureus.

    Jennifer Fishovitz;Juan A. Hermoso;Mayland Chang;Shahriar Mobashery

  • Critical involvement of a carbamylated lysine in catalytic function of class D beta-lactamases.

    Dasantila Golemi;Laurent Maveyraud;Sergei Vakulenko;Jean-Pierre Samama

  • How allosteric control of Staphylococcus aureus penicillin binding protein 2a enables methicillin resistance and physiological function

    Lisandro H. Otero;Alzoray Rojas-Altuve;Leticia I. Llarrull;Cesar Carrasco-López

  • Discoidin domain receptors: unique receptor tyrosine kinases in collagen-mediated signaling.

    Hsueh Liang Fu;Rajeshwari R. Valiathan;Richard Arkwright;Anjum Sohail

  • Aminoglycosides Modified by Resistance Enzymes Display Diminished Binding to the Bacterial Ribosomal Aminoacyl-tRNA Site

    Beatriz Llano-Sotelo;Eduardo F. Azucena;Lakshmi P. Kotra;Shahriar Mobashery

  • Potent and Selective Mechanism-Based Inhibition of Gelatinases

    Stephen Brown;M. Margarida Bernardo;§ Zhi-Hong Li;Lakshmi P. Kotra

  • Substrate Hydrolysis by Matrix Metalloproteinase-9*

    Steven J. Kridel;Emily Chen;Lakshmi P. Kotra;Eric W. Howard

  • Mechanism of anchoring of OmpA protein to the cell wall peptidoglycan of the gram-negative bacterial outer membrane

    Jeong Soon Park;Woo Cheol Lee;Kwon Joo Yeo;Kyoung-Seok Ryu

  • Cell surface association of matrix metalloproteinase-9 (gelatinase B)

    Rafael Fridman;Marta Toth;Irina Chvyrkova;Samy O. Meroueh

  • Characterization of the Monomeric and Dimeric Forms of Latent and Active Matrix Metalloproteinase-9 DIFFERENTIAL RATES FOR ACTIVATION BY STROMELYSIN 1

    Matthew W. Olson;M. Margarida Bernardo;Martin Pietila;David C. Gervasi

  • Ab initio QM/MM study of class a β-lactamase acylation : Dual participation of Glu166 and Lys73 in a concerted base promotion of Ser70

    Samy O. Meroueh;Jed F. Fisher;H. Bernhard Schlegel;Shahriar Mobashery

Frequent Co-Authors

Rafael Fridman
Rafael Fridman Wayne State University
Jed F. Fisher
Jed F. Fisher University of Notre Dame
Juan A. Hermoso
Juan A. Hermoso Spanish National Research Council
H. Bernhard Schlegel
H. Bernhard Schlegel Wayne State University
Se Won Suh
Se Won Suh Seoul National University
Waldemar Vollmer
Waldemar Vollmer Newcastle University
Lionel Mourey
Lionel Mourey Federal University of Toulouse Midi-Pyrénées
Alex Y. Strongin
Alex Y. Strongin Sanford Burnham Prebys Medical Discovery Institute
Irit Sagi
Irit Sagi Weizmann Institute of Science
Birgitta Henriques-Normark
Birgitta Henriques-Normark Karolinska Institute

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