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Christopher M. Overall

Christopher M. Overall

University of British Columbia
Canada

Award Badge
Biology and Biochemistry
Canada
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
109
Citations
42112
World Ranking
1009
National Ranking
25

Christopher M. Overall publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Christopher M. Overall sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 339 publications — 84th percentile

84% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Christopher M. Overall D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Christopher M. Overall sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 109 D-Index — 95th percentile

95% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Canada Leader Award

Overview

Christopher M. Overall is affiliated with the University of British Columbia in Canada. Their research focuses primarily on the fields of Biochemistry, Genetics and Molecular Biology, and Medicine.

Within these broad fields, their subfields of specialization include Molecular Biology, Spectroscopy, Oncology, Immunology, and Infectious Diseases. Their work covers a range of topics, including Advanced Proteomics Techniques and Applications, Machine Learning in Bioinformatics, Peptidase Inhibition and Analysis, RNA and protein synthesis mechanisms, SARS-CoV-2 and COVID-19 Research, Protease and Inhibitor Mechanisms, and interferon and immune responses.

Christopher M. Overall has published in several scientific journals, with frequent contributions to the Journal of Proteome Research, bioRxiv (Cold Spring Harbor Laboratory), IUPHAR/BPS Guide to Pharmacology CITE, Cell Reports, and Journal of Virology.

The scientist's recent papers include:

  • A high-stringency blueprint of the human proteome (2020), published in Nature Communications
  • Mechanistic insights into COVID-19 by global analysis of the SARS-CoV-2 3CLpro substrate degradome (2021), published in Cell Reports
  • Classification and Nomenclature of Metacaspases and Paracaspases: No More Confusion with Caspases (2020), published in Molecular Cell
  • Experimental autoimmune encephalomyelitis is associated with changes of the microbiota composition in the gastrointestinal tract (2020), published in Scientific Reports
  • DIPPER, a spatiotemporal proteomics atlas of human intervertebral discs for exploring ageing and degeneration dynamics (2020), published in eLife

Frequent collaborators in their research include:

  • Nestor Solis
  • Gilbert S. Omenn
  • Cecilia Lindskog
  • Robert L. Moritz
  • Ruedi Aebersold

Best Publications

  • Strategies for MMP inhibition in cancer: innovations for the post-trial era

    Christopher Mark Overall;Carlos López-Otín

  • Validating matrix metalloproteinases as drug targets and anti-targets for cancer therapy

    Christopher M. Overall;Oded Kleifeld

  • Human and mouse proteases: a comparative genomic approach

    Xose S. Puente;Luis M. Sánchez;Christopher M. Overall;Carlos López-Otín

  • Multi-step pericellular proteolysis controls the transition from individual to collective cancer cell invasion

    Katarina Wolf;Yi I. Wu;Yi I. Wu;Yueying Liu;Jörg Geiger

  • Inflammation dampened by gelatinase A cleavage of monocyte chemoattractant protein-3.

    G. Angus McQuibban;Jiang-Hong Gong;Eric M. Tam;Christopher A. G. McCulloch

  • Protease degradomics: a new challenge for proteomics.

    Carlos López-Otín;Christopher M. Overall

  • Independent regulation of collagenase, 72-kDa progelatinase, and metalloendoproteinase inhibitor expression in human fibroblasts by transforming growth factor-beta.

    C M Overall;J L Wrana;J Sodek

  • Targeting Tumor Hypoxia: Suppression of Breast Tumor Growth and Metastasis by Novel Carbonic Anhydrase IX Inhibitors

    Yuanmei Lou;Paul C McDonald;Arusha Oloumi;Stephen K. Chia

  • Matrix Metalloproteinase Activity Inactivates the CXC Chemokine Stromal Cell-derived Factor-1

    G. Angus McQuibban;Georgina S. Butler;Jiang Hong Gong;Linda Bendall

  • Matrix metalloproteinase processing of monocyte chemoattractant proteins generates CC chemokine receptor antagonists with anti-inflammatory properties in vivo

    G. Angus McQuibban;Jiang-Hong Gong;Julie P. Wong;John L. Wallace

  • Molecular determinants of metalloproteinase substrate specificity: matrix metalloproteinase substrate binding domains, modules, and exosites.

    Christopher M Overall

  • Matrix metalloproteinases: what do they not do? New substrates and biological roles identified by murine models and proteomics.

    David Rodríguez;Charlotte J. Morrison;Christopher M. Overall

  • Transcriptional and post-transcriptional regulation of 72-kDa gelatinase/type IV collagenase by transforming growth factor-beta 1 in human fibroblasts. Comparisons with collagenase and tissue inhibitor of matrix metalloproteinase gene expression.

    C M Overall;J L Wrana;J Sodek

  • Isotopic labeling of terminal amines in complex samples identifies protein N-termini and protease cleavage products

    Oded Kleifeld;Alain Doucet;Ulrich auf dem Keller;Anna Prudova

  • Antisense RNA-induced reduction in murine TIMP levels confers oncogenicity on Swiss 3T3 cells.

    Rama Khokha;Paul Waterhouse;Simcha Yagel;Peeyush K. Lala

  • Loss of collagenase-2 confers increased skin tumor susceptibility to male mice

    Milagros Balbín;Antonio Fueyo;Angus M Tester;Alberto M Pendás

  • Microbiota and crevicular fluid collagenase activity in the osseointegrated dental implant sulcus: a comparison of sites in edentulous and partially edentulous patients.

    P. Apse;R. P. Ellen;C. M. Overall;G. A. Zarb

  • Proteome-derived, database-searchable peptide libraries for identifying protease cleavage sites.

    Oliver Schilling;Christopher M Overall

  • Towards third generation matrix metalloproteinase inhibitors for cancer therapy.

    Christopher M Overall;Oded Kleifeld

  • In search of partners: linking extracellular proteases to substrates

    Christopher M. Overall;Carl P. Blobel

Frequent Co-Authors

Gilbert S. Omenn
Gilbert S. Omenn University of Michigan–Ann Arbor
Jaro Sodek
Jaro Sodek University of Toronto
Eric W. Deutsch
Eric W. Deutsch University of Washington
Oliver Schilling
Oliver Schilling University of Freiburg
Young Ki Paik
Young Ki Paik Yonsei University
Christopher A. McCulloch
Christopher A. McCulloch University of Toronto
Jayachandran N. Kizhakkedathu
Jayachandran N. Kizhakkedathu University of British Columbia
Mark S. Baker
Mark S. Baker Macquarie University
Jennifer E. Van Eyk
Jennifer E. Van Eyk Cedars-Sinai Medical Center
Carlos López-Otín
Carlos López-Otín University of Oviedo

External Links

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Related Online Degrees & Career Pathways

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Best Scientists Citing Christopher M. Overall

Claudiu T. Supuran

Claudiu T. Supuran

University of Florence

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Timo Sorsa

Timo Sorsa

University of Helsinki

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Gregg B. Fields

Gregg B. Fields

Florida Atlantic University

Publications: 108

Carlos López-Otín

Carlos López-Otín

University of Oviedo

Publications: 84

Ghislain Opdenakker

Ghislain Opdenakker

Rega Institute for Medical Research

Publications: 80

Tuula Salo

Tuula Salo

University of Helsinki

Publications: 77

Oliver Schilling

Oliver Schilling

University of Freiburg

Publications: 68

Dylan R. Edwards

Dylan R. Edwards

University of East Anglia

Publications: 62

Peter Friedl

Peter Friedl

Radboud University Medical Center

Publications: 60

Hideaki Nagase

Hideaki Nagase

University of Oxford

Publications: 60

Gillian Murphy

Gillian Murphy

University of Cambridge

Publications: 59

Motoharu Seiki

Motoharu Seiki

University of Tokyo

Publications: 59

Agnès Noël

Agnès Noël

University of Liège

Publications: 57

Merry L. Lindsey

Merry L. Lindsey

University of Nebraska Medical Center

Publications: 50

Fabrizio Carta

Fabrizio Carta

University of Florence

Publications: 50

Alex Y. Strongin

Alex Y. Strongin

Sanford Burnham Prebys Medical Discovery Institute

Publications: 48

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