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Biology and Biochemistry
UK
2026

D-Index & Metrics

Biology and Biochemistry

D-Index
112
Citations
59515
World Ranking
880
National Ranking
48

Hideaki Nagase publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Hideaki Nagase sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 383 publications — 88th percentile

88% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Hideaki Nagase D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Hideaki Nagase sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 112 D-Index — 96th percentile

96% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in United Kingdom Leader Award
  • 2025 - Research.com Biology and Biochemistry in United Kingdom Leader Award
  • 2023 - Research.com Biology and Biochemistry in United Kingdom Leader Award

Overview

Hideaki Nagase is affiliated with the University of Oxford in the United Kingdom and has an extensive publication record in the fields of Medicine and Biochemistry, Genetics, and Molecular Biology. Their work spans various subfields, including Cancer Research, Molecular Biology, Cell Biology, Rheumatology, and Immunology and Allergy.

The scientist's research addresses multiple topics such as Protease and Inhibitor Mechanisms, Calpain Protease Function and Regulation, Osteoarthritis Treatment and Mechanisms, Cell Adhesion Molecules Research, Ion Channel Regulation and Function, Pain Mechanisms and Treatments, and Blood Coagulation and Thrombosis Mechanisms.

Notable recent papers include:

  • TIMP-3 facilitates binding of target metalloproteinases to the endocytic receptor LRP-1 and promotes scavenging of MMP-1 (2020, Scientific Reports)
  • A top-down approach to uncover the hidden ligandome of low-density lipoprotein receptor-related protein 1 in cartilage (2022, Matrix Biology)
  • Interleukin 13 (IL-13)-regulated expression of the chondroprotective metalloproteinase ADAM15 is reduced in aging cartilage (2020, Osteoarthritis and Cartilage Open)
  • ADAM17 Mediates Proteolytic Maturation of Voltage-Gated Calcium Channel Auxiliary α2δ Subunits, and Enables Calcium Current Enhancement (2022, Function)
  • Uncovering the ligandome of low-density lipoprotein receptor-related protein 1 in cartilage: a top-down approach to identify therapeutic targets (2022, bioRxiv [Cold Spring Harbor Laboratory])

Frequent collaborators in their research include Simone Bonelli, Linda Troeberg, Simone Dario Scilabra, Kazuhiro Yamamoto, and Abdulrahman M E Gremida. These collaborations are reflected in multiple joint publications.

Common venues for publishing Hideaki Nagase's research are bioRxiv (Cold Spring Harbor Laboratory), Scientific Reports, Matrix Biology, Osteoarthritis and Cartilage Open, and Function, showing a consistent presence in journals covering molecular biology and medical research.

Best Publications

  • Matrix metalloproteinases and tissue inhibitors of metalloproteinases: structure, function, and biochemistry.

    Robert Visse;Hideaki Nagase

  • Structure and function of matrix metalloproteinases and TIMPs

    Hideaki Nagase;Robert Visse;Gillian Murphy

  • Tissue inhibitors of metalloproteinases: evolution, structure and function.

    Keith Brew;Deendayal Dinakarpandian;Hideaki Nagase;Hideaki Nagase

  • Activation mechanisms of matrix metalloproteinases.

    Nagase H

  • The tissue inhibitors of metalloproteinases (TIMPs): An ancient family with structural and functional diversity

    Keith Brew;Hideaki Nagase

  • Progress in matrix metalloproteinase research.

    Gillian Murphy;Hideaki Nagase

  • Purification and cloning of aggrecanase-1: a member of the ADAMTS family of proteins.

    M. D. Tortorella;T. C. Burn;M. A. Pratta;I. Abbaszade

  • Activation of Matrix Metalloproteinase-9 (MMP-9) via a Converging Plasmin/Stromelysin-1 Cascade Enhances Tumor Cell Invasion

    Noemi Ramos-DeSimone;Elizabeth Hahn-Dantona;John Sipley;Hideaki Nagase

  • Mechanism of inhibition of the human matrix metalloproteinase stromelysin-1 by TIMP-1.

    Franz-Xaver Gomis-Rüth;Klaus Maskos;Michael Betz;Andreas Bergner

  • Matrix metalloproteinase 3 (stromelysin) activates the precursor for the human matrix metalloproteinase 9.

    Y Ogata;J.J. Enghild;H Nagase

  • Proteases involved in cartilage matrix degradation in osteoarthritis

    Linda Troeberg;Hideaki Nagase

  • TIMP-3 Is a Potent Inhibitor of Aggrecanase 1 (ADAM-TS4) and Aggrecanase 2 (ADAM-TS5)

    Masahide Kashiwagi;Masahide Kashiwagi;Micky Tortorella;Hideaki Nagase;Keith Brew

  • Mechanisms of activation of tissue procollagenase by matrix metalloproteinase 3 (stromelysin).

    Ko Suzuki;Jan J. Enghild;Tatsuhisa Morodomi;Guy Salvesen

  • Inhibition of apoptosis of activated hepatic stellate cells by tissue inhibitor of metalloproteinase-1 is mediated via effects on matrix metalloproteinase inhibition. Implications for reversibility of liver fibrosis

    Frank R. Murphy;Razao Issa;Xiaoying Zhou;Shabna Ratnarajah

  • Cloning and characterization of ADAMTS11, an aggrecanase from the ADAMTS family.

    Ilgar Abbaszade;Rui-Qin Liu;Fude Yang;Stuart A. Rosenfeld

  • Aggrecanases and cartilage matrix degradation.

    Hideaki Nagase;Masahide Kashiwagi

  • Collagenase unwinds triple-helical collagen prior to peptide bond hydrolysis

    Linda Chung;Linda Chung;Deendayal Dinakarpandian;Naoto Yoshida;Janelle L Lauer-Fields;Janelle L Lauer-Fields

  • Degradation of interleukin 1beta by matrix metalloproteinases.

    Akira Ito;Akihira Mukaiyama;Yoshifumi Itoh;Hideaki Nagase

  • Regulation of matrix metalloproteinases (MMP-2, -3, -9, and -13) by interleukin-1 and interleukin-6 in mouse calvaria : Association of MMP induction with bone resorption

    Kenichiro Kusano;Chisato Miyaura;Masaki Inada;Tatsuya Tamura

  • Matrix metalloproteinases and TIMPs

    J. F. Woessner;Hideaki Nagase

Frequent Co-Authors

Yoshifumi Itoh
Yoshifumi Itoh University of Oxford
Gillian Murphy
Gillian Murphy University of Cambridge
Jan J. Enghild
Jan J. Enghild Aarhus University
Keith Brew
Keith Brew Florida Atlantic University
Gregg B. Fields
Gregg B. Fields Florida Atlantic University
Jeremy Saklatvala
Jeremy Saklatvala University of Oxford
Motoharu Seiki
Motoharu Seiki University of Tokyo
Guy S. Salvesen
Guy S. Salvesen Sanford Burnham Prebys Medical Discovery Institute
George Bou-Gharios
George Bou-Gharios University of Liverpool
Klaus Maskos
Klaus Maskos Proteros biostructures GmbH

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