What is he best known for?
The fields of study he is best known for:
Matrix metalloproteinase, Biochemistry, Cell biology, Extracellular matrix and Matrix Metalloproteinase 3 are his primary areas of study.
Hideaki Nagase has included themes like Molecular biology, Matrix and Immunology, Arthritis in his Matrix metalloproteinase study.
The concepts of his Biochemistry study are interwoven with issues in Aggrecan and Aggrecanase.
His Cell biology research includes elements of Cell, Morphogenesis, Cell growth and Connective tissue.
His Extracellular matrix research is multidisciplinary, incorporating perspectives in Cell migration, Substrate specificity, Ternary complex, Signal transduction and Metastasis.
His Matrix Metalloproteinase 3 research is multidisciplinary, incorporating elements of Plasmin, Collagenase and Protein precursor.
His most cited work include:
- Matrix metalloproteinases and tissue inhibitors of metalloproteinases: structure, function, and biochemistry. (3599 citations)
- Structure and function of matrix metalloproteinases and TIMPs (2211 citations)
- Tissue inhibitors of metalloproteinases: evolution, structure and function. (1612 citations)
What are the main themes of his work throughout his whole career to date?
Hideaki Nagase mainly investigates Matrix metalloproteinase, Biochemistry, Cell biology, Extracellular matrix and Molecular biology.
Hideaki Nagase combines subjects such as Stereochemistry and Collagenase, Enzyme with his study of Matrix metalloproteinase.
His Biochemistry study deals with Type I collagen intersecting with Triple helix.
His Cell biology study combines topics in areas such as Cell, Cell migration, Cell membrane and Morphogenesis.
His Extracellular matrix study integrates concerns from other disciplines, such as Extracellular, Receptor, Wound healing and Arthritis.
His Molecular biology research includes themes of Activator, Gelatinase A, Zebrafish and Tissue inhibitor of metalloproteinase.
He most often published in these fields:
- Matrix metalloproteinase (61.77%)
- Biochemistry (37.95%)
- Cell biology (24.38%)
What were the highlights of his more recent work (between 2013-2021)?
- Cell biology (24.38%)
- Matrix metalloproteinase (61.77%)
- Cartilage (9.42%)
In recent papers he was focusing on the following fields of study:
His primary areas of study are Cell biology, Matrix metalloproteinase, Cartilage, Biochemistry and Internal medicine.
He interconnects Chondrocyte, Endochondral ossification and Osteoblast lineage in the investigation of issues within Cell biology.
Hideaki Nagase combines subjects such as Extracellular matrix, Immunology and Enzyme with his study of Matrix metalloproteinase.
His biological study spans a wide range of topics, including Extracellular, Anatomy and Thrombospondin.
His study on Cartilage also encompasses disciplines like
- In vivo which intersects with area such as Pathology and Arthritis,
- Aggrecan, which have a strong connection to Glycosaminoglycan, Proteoglycan, Western blot and Gene expression.
In his study, Osteoclast and Androgen receptor is strongly linked to Endocrinology, which falls under the umbrella field of Internal medicine.
Between 2013 and 2021, his most popular works were:
- YAP is essential for tissue tension to ensure vertebrate 3D body shape (149 citations)
- Tissue inhibitor of metalloproteinases-1 induces a pro-tumourigenic increase of miR-210 in lung adenocarcinoma cells and their exosomes. (96 citations)
- Tissue inhibitor of metalloproteinases (TIMP)‐1 creates a premetastatic niche in the liver through SDF‐1/CXCR4‐dependent neutrophil recruitment in mice (86 citations)
In his most recent research, the most cited papers focused on:
His primary areas of investigation include Biochemistry, ADAMTS, Molecular biology, Cell biology and Aggrecan.
The Biochemistry study combines topics in areas such as Cartilage metabolism and In vivo.
His studies deal with areas such as Plasma protein binding, Disintegrin and Aggrecanase as well as ADAMTS.
His Cell biology research integrates issues from Proteases and Adenocarcinoma.
His work carried out in the field of Extracellular matrix brings together such families of science as Proteolysis, Matrix metalloproteinase, Collagenase and Motility.
His Matrix metalloproteinase research includes themes of Protein kinase B, Human umbilical vein endothelial cell, Downregulation and upregulation, Tube formation and PI3K/AKT/mTOR pathway.
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