2023 - Research.com Biology and Biochemistry in United Kingdom Leader Award
Matrix metalloproteinase, Biochemistry, Cell biology, Extracellular matrix and Matrix Metalloproteinase 3 are his primary areas of study. Hideaki Nagase has included themes like Molecular biology, Matrix and Immunology, Arthritis in his Matrix metalloproteinase study. The concepts of his Biochemistry study are interwoven with issues in Aggrecan and Aggrecanase.
His Cell biology research includes elements of Cell, Morphogenesis, Cell growth and Connective tissue. His Extracellular matrix research is multidisciplinary, incorporating perspectives in Cell migration, Substrate specificity, Ternary complex, Signal transduction and Metastasis. His Matrix Metalloproteinase 3 research is multidisciplinary, incorporating elements of Plasmin, Collagenase and Protein precursor.
Hideaki Nagase mainly investigates Matrix metalloproteinase, Biochemistry, Cell biology, Extracellular matrix and Molecular biology. Hideaki Nagase combines subjects such as Stereochemistry and Collagenase, Enzyme with his study of Matrix metalloproteinase. His Biochemistry study deals with Type I collagen intersecting with Triple helix.
His Cell biology study combines topics in areas such as Cell, Cell migration, Cell membrane and Morphogenesis. His Extracellular matrix study integrates concerns from other disciplines, such as Extracellular, Receptor, Wound healing and Arthritis. His Molecular biology research includes themes of Activator, Gelatinase A, Zebrafish and Tissue inhibitor of metalloproteinase.
His primary areas of study are Cell biology, Matrix metalloproteinase, Cartilage, Biochemistry and Internal medicine. He interconnects Chondrocyte, Endochondral ossification and Osteoblast lineage in the investigation of issues within Cell biology. Hideaki Nagase combines subjects such as Extracellular matrix, Immunology and Enzyme with his study of Matrix metalloproteinase.
His biological study spans a wide range of topics, including Extracellular, Anatomy and Thrombospondin. His study on Cartilage also encompasses disciplines like
His primary areas of investigation include Biochemistry, ADAMTS, Molecular biology, Cell biology and Aggrecan. The Biochemistry study combines topics in areas such as Cartilage metabolism and In vivo. His studies deal with areas such as Plasma protein binding, Disintegrin and Aggrecanase as well as ADAMTS.
His Cell biology research integrates issues from Proteases and Adenocarcinoma. His work carried out in the field of Extracellular matrix brings together such families of science as Proteolysis, Matrix metalloproteinase, Collagenase and Motility. His Matrix metalloproteinase research includes themes of Protein kinase B, Human umbilical vein endothelial cell, Downregulation and upregulation, Tube formation and PI3K/AKT/mTOR pathway.
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Matrix metalloproteinases and tissue inhibitors of metalloproteinases: structure, function, and biochemistry.
Robert Visse;Hideaki Nagase.
Circulation Research (2003)
Structure and function of matrix metalloproteinases and TIMPs
Hideaki Nagase;Robert Visse;Gillian Murphy.
Cardiovascular Research (2006)
Tissue inhibitors of metalloproteinases: evolution, structure and function.
Keith Brew;Deendayal Dinakarpandian;Hideaki Nagase;Hideaki Nagase.
Biochimica et Biophysica Acta (2000)
Activation mechanisms of matrix metalloproteinases.
Biological Chemistry (1997)
The tissue inhibitors of metalloproteinases (TIMPs): An ancient family with structural and functional diversity
Keith Brew;Hideaki Nagase.
Biochimica et Biophysica Acta (2010)
Activation of Matrix Metalloproteinase-9 (MMP-9) via a Converging Plasmin/Stromelysin-1 Cascade Enhances Tumor Cell Invasion
Noemi Ramos-DeSimone;Elizabeth Hahn-Dantona;John Sipley;Hideaki Nagase.
Journal of Biological Chemistry (1999)
Purification and cloning of aggrecanase-1: a member of the ADAMTS family of proteins.
M. D. Tortorella;T. C. Burn;M. A. Pratta;I. Abbaszade.
Mechanism of inhibition of the human matrix metalloproteinase stromelysin-1 by TIMP-1.
Franz-Xaver Gomis-Rüth;Klaus Maskos;Michael Betz;Andreas Bergner.
Progress in matrix metalloproteinase research.
Gillian Murphy;Hideaki Nagase.
Molecular Aspects of Medicine (2008)
Matrix metalloproteinase 3 (stromelysin) activates the precursor for the human matrix metalloproteinase 9.
Y Ogata;J.J. Enghild;H Nagase.
Journal of Biological Chemistry (1992)
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