World's Best Scientists 2026 revealed!

Overview

Adam J. Adler is affiliated with the University of Connecticut Health Center in the United States. Their research primarily focuses on the field of medicine, with a specialization in pulmonary and respiratory medicine, surgery, immunology, ophthalmology, and cardiology and cardiovascular medicine.

Their recent publications cover topics related to autoimmune diseases, genetic factors, and immunology, including studies on psoriasis, multiple sclerosis, and genetic epilepsy. Notable papers include:

  • "Serum Levels of miR-146a in Patients with Psoriasis" (2021) published in Molecular Diagnosis & Therapy
  • "Depression and anxiety in multiple sclerosis patients: The role of genetic variability of interleukin 1β" (2021) published in Multiple Sclerosis and Related Disorders
  • "Multiple autoimmune syndrome: Clinical, immunological and genotypic characterization" (2023) published in European Journal of Internal Medicine
  • "Immunogenetic protective factors in Genetic Generalized Epilepsy" (2020) published in Epilepsy Research
  • "Predictive Factors of Severe Behçet's disease: A Longitudinal, Prospective Cohort Followed Between 1981-2020" (2021) published in Reumatología Clínica

The research includes focus areas on lipoproteins and cardiovascular health, epilepsy research and treatment, ocular diseases including Behçet's syndrome, vasculitis and related conditions, retinal and optic conditions, antiplatelet therapy and cardiovascular diseases, as well as cytokine signaling pathways and interactions.

Frequent co-authors in Adam J. Adler's publications include Bárbara Leal, Ana Marta Ferreira, Sandra Brás, Paulo Costa, and Cláudia Carvalho.

The venues where they have published work include Molecular Diagnosis & Therapy, Multiple Sclerosis and Related Disorders, European Journal of Internal Medicine, Epilepsy Research, and Reumatología Clínica.

Adler has also authored a book titled Boas práticas para produção de alimentos seguros published by Even3 Publicações eBooks, scheduled for 2025.

Best Publications

  • Variants at multiple loci implicated in both innate and adaptive immune responses are associated with Sjogren's syndrome.

    Christopher J. Lessard;Christopher J. Lessard;He Li;He Li;Indra Adrianto;John A. Ice

  • CD4+ T Cell Tolerance to Parenchymal Self-Antigens Requires Presentation by Bone Marrow–derived Antigen-presenting Cells

    Adam J. Adler;David W. Marsh;Gregory S. Yochum;James L. Guzzo

  • Androgen ablation mitigates tolerance to a prostate/prostate cancer-restricted antigen

    Charles G. Drake;Amy D.H. Doody;Marianne A. Mihalyo;Ching Tai Huang

  • Macrophage polarization and meta-inflammation

    Chuan Li;Maria M. Xu;Kepeng Wang;Adam J. Adler

  • Evaluation of the TREX1 gene in a large multi-ancestral lupus cohort

    B. Namjou;P. H. Kothari;J. A. Kelly;S. B. Glenn

  • Lymphatic endothelial cells induce tolerance via PD-L1 and lack of costimulation leading to high-level PD-1 expression on CD8 T cells.

    Eric F. Tewalt;Jarish N. Cohen;Sherin J. Rouhani;Cynthia J. Guidi

  • High-density genotyping of immune-related loci identifies new SLE risk variants in individuals with Asian ancestry

    Celi Sun;Julio E. Molineros;Loren L. Looger;Xu Jie Zhou

  • Tc17 CD8 T cells: functional plasticity and subset diversity.

    Hung Rong Yen;Timothy J. Harris;Satoshi Wada;Joseph F. Grosso

  • Association of Genetic Variants in Complement Factor H and Factor H-Related Genes with Systemic Lupus Erythematosus Susceptibility

    Jian Zhao;Hui Wu;Melanie Khosravi;Huijuan Cui

  • Identification of IRF8, TMEM39A, and IKZF3-ZPBP2 as Susceptibility Loci for Systemic Lupus Erythematosus in a Large-Scale Multiracial Replication Study

    Christopher J. Lessard;Christopher J. Lessard;Christopher J. Lessard;Indra Adrianto;John A. Ice;Graham B. Wiley

  • Androgen-specific gene activation via a consensus glucocorticoid response element is determined by interaction with nonreceptor factors

    Adam J. Adler;Mark Danielsen;Diane M. Robins

  • CD134 Plus CD137 Dual Costimulation Induces Eomesodermin in CD4 T Cells To Program Cytotoxic Th1 Differentiation

    Harry Z. Qui;Adam T. Hagymasi;Suman Bandyopadhyay;Marie-Clare St. Rose

  • Glycoprotein 96 can chaperone both MHC class I- and class II-restricted epitopes for in vivo presentation, but selectively primes CD8+ T cell effector function.

    Amy D. H. Doody;Joseph T. Kovalchin;Marianne A. Mihalyo;Adam T. Hagymasi

  • Genome‐Wide Association Study in an Amerindian Ancestry Population Reveals Novel Systemic Lupus Erythematosus Risk Loci and the Role of European Admixture

    Marta E. Alarcón-Riquelme;Julie T. Ziegler;Julio Molineros;Timothy D. Howard

  • The stringency and magnitude of androgen-specific gene activation are combinatorial functions of receptor and nonreceptor binding site sequences.

    Adam J. Adler;Arno Scheller;Diane M. Robins

  • Multiple components of a complex androgen-dependent enhancer.

    Adam J. Adler;Arno Scheller;Yetta Hoffman;Diane M. Robins

  • Development and characterization of a cytokine-secreting pancreatic adenocarcinoma vaccine from primary tumors for use in clinical trials.

    Elizabeth M. Jaffee;Mieke Schutte;Jeanette Gossett;Laura A. Morsberger

  • Genome-Wide Association Study of African and European Americans Implicates Multiple Shared and Ethnic Specific Loci in Sarcoidosis Susceptibility

    Indra Adrianto;Chee Paul Lin;Jessica J. Hale;Albert M. Levin

  • Admixture Mapping in Lupus Identifies Multiple Functional Variants within IFIH1 Associated with Apoptosis, Inflammation, and Autoantibody Production

    Julio E. Molineros;Amit K. Maiti;Celi Sun;Loren L. Looger

  • In Vivo CD4+ T Cell Tolerance Induction Versus Priming Is Independent of the Rate and Number of Cell Divisions

    Adam J. Adler;Ching Tai Huang;Gregory S. Yochum;David W. Marsh;David W. Marsh

Frequent Co-Authors

Anthony T. Vella
Anthony T. Vella University of Connecticut Health Center
Suzanne L. Topalian
Suzanne L. Topalian Johns Hopkins University
Stephen K. Wikel
Stephen K. Wikel Quinnipiac University
Robert S. Mittler
Robert S. Mittler Emory University
Elizabeth M. Jaffee
Elizabeth M. Jaffee Johns Hopkins University
Alexander C. Lichtler
Alexander C. Lichtler University of Connecticut Health Center
Michael G. Tovey
Michael G. Tovey École Normale Supérieure Paris-Saclay
Kevin P. Claffey
Kevin P. Claffey University of Connecticut Health Center
Constance A. Griffin
Constance A. Griffin Johns Hopkins University

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