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Microbiology

D-Index
57
Citations
10907
World Ranking
3597
National Ranking
1418

Overview

Anthony T. Vella is affiliated with the University of Connecticut Health Center in the United States. Their research spans multiple areas within biomedical science, with a strong focus on immunology, molecular biology, and medicine. They have contributed extensively to the study of immune responses, inflammation, and cardiovascular diseases.

Their main fields of study include:

  • Medicine
  • Immunology and Microbiology
  • Biochemistry, Genetics and Molecular Biology

Within these domains, their subfields of research emphasize:

  • Immunology
  • Molecular Biology
  • Epidemiology
  • Oncology
  • Cancer Research

The scientist's primary research topics cover diverse immunological and molecular mechanisms, such as:

  • Interferon and immune responses
  • Immune cell function and interaction
  • Atherosclerosis and cardiovascular diseases
  • Cell adhesion molecules research
  • Immune response and inflammation
  • Inflammasome and immune disorders
  • Single-cell and spatial transcriptomics

Anthony T. Vella has frequently published in the following venues:

  • The Journal of Immunology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Circulation
  • Proceedings of the National Academy of Sciences
  • Scientific Reports

Some of their recent publications illustrate the breadth of their work:

  • "Bioactive polymeric materials and electrical stimulation strategies for musculoskeletal tissue repair and regeneration," 2020, Bioactive Materials
  • "Intracellular immune sensing promotes inflammation via gasdermin D-driven release of a lectin alarmin," 2021, Nature Immunology
  • "A high OXPHOS CD8 T cell subset is predictive of immunotherapy resistance in melanoma patients," 2021, The Journal of Experimental Medicine
  • "Astrocyte Support for Oligodendrocyte Differentiation can be Conveyed via Extracellular Vesicles but Diminishes with Age," 2020, Scientific Reports
  • "AtheroSpectrum Reveals Novel Macrophage Foam Cell Gene Signatures Associated With Atherosclerotic Cardiovascular Disease Risk," 2021, Circulation

Their collaborative research involves frequent coauthors, including:

  • Antoine Ménoret
  • Beiyan Zhou
  • Penghua Wang
  • Tingting Geng
  • Andrew G. Harrison

Best Publications

  • Cutting edge: 4-1BB is a bona fide CD8 T cell survival signal.

    Chikara Takahashi;Robert S. Mittler;Anthony T. Vella

  • Cytokine-induced survival of activated T cells in vitro and in vivo

    Anthony T. Vella;Steven Dow;Terry A. Potter;John Kappler

  • Macrophage polarization and meta-inflammation

    Chuan Li;Maria M. Xu;Kepeng Wang;Adam J. Adler

  • Interleukin 4 (IL-4) or IL-7 prevents the death of resting T cells: stat6 is probably not required for the effect of IL-4.

    Anthony Vella;T. Kent Teague;James Ihle;John Kappler

  • Danger and OX40 receptor signaling synergize to enhance memory T cell survival by inhibiting peripheral deletion.

    Joseph R. Maxwell;Andrew Weinberg;Rodney A. Prell;Anthony T. Vella

  • Lipopolysaccharide interferes with the induction of peripheral T cell death

    Anthony T. Vella;James E. McCormack;Peter S. Linsley;John W. Kappler;John W. Kappler

  • CCR6-mediated dendritic cell activation of pathogen-specific T cells in Peyer's patches.

    Rosa Maria Salazar-Gonzalez;Jan H. Niess;David J. Zammit;Rajesh Ravindran

  • IL-6 rescues resting mouse T cells from apoptosis.

    T K Teague;P Marrack;J W Kappler;A T Vella

  • Lymphatic endothelial cells induce tolerance via PD-L1 and lack of costimulation leading to high-level PD-1 expression on CD8 T cells.

    Eric F. Tewalt;Jarish N. Cohen;Sherin J. Rouhani;Cynthia J. Guidi

  • Gasdermin D Restrains Type I Interferon Response to Cytosolic DNA by Disrupting Ionic Homeostasis

    Ishita Banerjee;Bharat Behl;Morena Mendonca;Morena Mendonca;Gaurav Shrivastava

  • CD4+ Th2 response induced by Schistosoma mansoni eggs develops rapidly, through an early, transient, Th0-like stage.

    A T Vella;E J Pearce

  • OX-40: life beyond the effector T cell stage.

    Andrew D. Weinberg;Anthony T. Vella;Michael Croft

  • Development of eosinophilic airway inflammation and airway hyperresponsiveness requires interleukin-5 but not immunoglobulin E or B lymphocytes.

    Eckard Hamelmann;Katsuyuki Takeda;Jurgen Schwarze;Anthony T. Vella

  • CD28 engagement and proinflammatory cytokines contribute to T cell expansion and long-term survival in vivo.

    A T Vella;T Mitchell;B Groth;P S Linsley

  • Cytokine-mediated disruption of lymphocyte trafficking, hemopoiesis, and induction of lymphopenia, anemia, and thrombocytopenia in anti-CD137-treated mice.

    Liguo Niu;Simona Strahotin;Becker Hewes;Benyue Zhang

  • CD134 Plus CD137 Dual Costimulation Induces Eomesodermin in CD4 T Cells To Program Cytotoxic Th1 Differentiation

    Harry Z. Qui;Adam T. Hagymasi;Suman Bandyopadhyay;Marie-Clare St. Rose

  • Allergic airway sensitization induces T cell activation but not airway hyperresponsiveness in B cell-deficient mice

    E. Hamelmann;A. T. Vella;A. Oshiba;J. W. Kappler

  • 4-1BB and OX40 Dual Costimulation Synergistically Stimulate Primary Specific CD8 T Cells for Robust Effector Function

    Seung-Joo Lee;Lara Myers;Guruprasaadh Muralimohan;Jie Dai

  • Understanding how lipopolysaccharide impacts CD4 T-cell immunity.

    Jeremy P. McAleer;Anthony T. Vella

  • Peptide-Specific CD8 T Regulatory Cells Use IFN-γ to Elaborate TGF-β-Based Suppression

    Lara Myers;Michael Croft;Byoung S. Kwon;Robert S. Mittler

Frequent Co-Authors

Adam J. Adler
Adam J. Adler University of Connecticut Health Center
Robert S. Mittler
Robert S. Mittler Emory University
Philippa Marrack
Philippa Marrack National Jewish Health
Byoung S. Kwon
Byoung S. Kwon Tulane University
John W. Kappler
John W. Kappler National Jewish Health
Erol Fikrig
Erol Fikrig Yale University
Leo Lefrançois
Leo Lefrançois University of Connecticut Health Center
Michael Croft
Michael Croft La Jolla Institute For Allergy & Immunology
Reinhard Laubenbacher
Reinhard Laubenbacher University of Florida
Stephen J. McSorley
Stephen J. McSorley University of California, Davis

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