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Immunology

D-Index
102
Citations
37737
World Ranking
674
National Ranking
389

Research.com Recognitions

  • 2019 - Distinguished Fellows of the American Association of Immunologists (AAI)
  • 2010 - American Association of Immunologists Lifetime Achievement Award
  • 2010 - AAI Lifetime Achievement Award, American Association of Immunologists
  • 2006 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Susan L. Swain is affiliated with the University of Massachusetts Chan Medical School in the United States. Their research primarily focuses on immunology and microbiology, with a specialization in immunology as indicated by the majority of their publications.

Their main fields of study include:

  • Immunology and Microbiology

Within these fields, their work covers several subfields such as:

  • Immunology
  • Epidemiology
  • Oncology
  • Molecular Biology
  • Radiology, Nuclear Medicine and Imaging

The scientist's topics of interest span a range of immune-related areas, including:

  • Immune Cell Function and Interaction
  • T-cell and B-cell Immunology
  • Immunotherapy and Immune Responses
  • Immune Response and Inflammation
  • IL-33, ST2, and ILC Pathways
  • Influenza Virus Research Studies
  • CAR-T cell therapy research

Frequent venues for their publications include:

  • The Journal of Immunology (6 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (3 publications)
  • Cell Reports (2 publications)
  • Proceedings of the National Academy of Sciences (1 publication)
  • Aging Cell (1 publication)

Selected recent publications by Susan L. Swain are:

  • Strong influenza-induced T FH generation requires CD4 effectors to recognize antigen locally and receive signals from continuing infection, 2022, Proceedings of the National Academy of Sciences
  • CD25-Targeted IL-2 Signals Promote Improved Outcomes of Influenza Infection and Boost Memory CD4 T Cell Formation, 2020, The Journal of Immunology
  • Influenza Vaccine-Induced CD4 Effectors Require Antigen Recognition at an Effector Checkpoint to Generate CD4 Lung Memory and Antibody Production, 2020, The Journal of Immunology
  • Bona Fide Th17 Cells without Th1 Functional Plasticity Protect against Influenza, 2022, The Journal of Immunology
  • IgD + age-associated B cells are the progenitors of the main T-independent B cell response to infection that generates protective Ab and can be induced by an inactivated vaccine in the aged, 2022, Aging Cell

Collaborators frequently working with Susan L. Swain include:

  • Priyadharshini Devarajan
  • Olivia Kugler-Umana
  • Catherine H. Castonguay
  • Michael C. Jones
  • Allen M. Vong

Over the course of their career, Susan L. Swain has been recognized with several awards:

  • Distinguished Fellows of the American Association of Immunologists (AAI), 2019
  • American Association of Immunologists Lifetime Achievement Award, 2010
  • AAI Lifetime Achievement Award, American Association of Immunologists, 2010
  • Fellow of the American Association for the Advancement of Science (AAAS), 2006

Best Publications

  • IL-23 and IL-17 in the establishment of protective pulmonary CD4 + T cell responses after vaccination and during Mycobacterium tuberculosis challenge

    Shabaana A Khader;Guy K Bell;John E Pearl;Jeffrey J Fountain

  • IL-4 directs the development of Th2-like helper effectors.

    S L Swain;A D Weinberg;M English;G Huston

  • Expanding roles for CD4 + T cells in immunity to viruses

    Susan L. Swain;K. Kai McKinstry;Tara M. Strutt

  • Reciprocal regulation of polarized cytokine production by effector B and T cells.

    David P. Harris;Laura Haynes;Peter C. Sayles;Debra K. Duso

  • T cell memory.

    R W Dutton;L M Bradley;S L Swain

  • T cell subsets and the recognition of MHC class.

    Susan L. Swain

  • Naive versus memory CD4 T cell response to antigen. Memory cells are less dependent on accessory cell costimulation and can respond to many antigen-presenting cell types including resting B cells.

    M Croft;L M Bradley;S L Swain

  • Preferential induction of a Th1 immune response and inhibition of specific IgE antibody formation by plasmid DNA immunization

    Eyal Raz;Helen Tighe;Yukio Sato;Maripat Corr

  • Generation of polarized antigen-specific CD8 effector populations: reciprocal action of interleukin (IL)-4 and IL-12 in promoting type 2 versus type 1 cytokine profiles.

    Michael Croft;Laura Carter;Susan L. Swain;Richard W. Dutton

  • Class II-Independent Generation of CD4 Memory T Cells from Effectors

    Susan L. Swain;Hui Hu;Gail Huston

  • Unequal Death in T Helper Cell (Th)1 and Th2 Effectors: Th1, but not Th2, Effectors Undergo Rapid Fas/FasL-mediated Apoptosis

    Xiaohong Zhang;Thomas Brunner;Laura Carter;Richard W. Dutton

  • Helper T-cell subsets: phenotype, function and the role of lymphokines in regulating their development.

    Susan L. Swain;Linda M. Bradley;Michael Croft;Susan Tonkonogy

  • Tc17, a Unique Subset of CD8 T Cells That Can Protect against Lethal Influenza Challenge

    Hiromasa Hamada;Maria de la Luz Garcia-Hernandez;Joyce B. Reome;Sara K. Misra

  • CD4 effector T cell subsets in the response to influenza: heterogeneity, migration, and function.

    Eulogia Román;Ellen Miller;Allen G. Harmsen;James Wiley

  • Interferon γ Eliminates Responding Cd4 T Cells during Mycobacterial Infection by Inducing Apoptosis of Activated Cd4 T Cells

    Dyana K. Dalton;Laura Haynes;Cong Qiu Chu;Susan L. Swain

  • Interleukin 12p40 is required for dendritic cell migration and T cell priming after Mycobacterium tuberculosis infection

    Shabaana A. Khader;Santiago Partida-Sanchez;Guy Bell;Dawn M. Jelley-Gibbs

  • Qualitative Changes Accompany Memory T Cell Generation: Faster, More Effective Responses at Lower Doses of Antigen

    Paul R. Rogers;Caroline Dubey;Susan L. Swain

  • IL-10 Deficiency Unleashes an Influenza-Specific Th17 Response and Enhances Survival against High-Dose Challenge

    K. Kai McKinstry;Tara M. Strutt;Amanda Buck;Jonathan D. Curtis

  • IL-7 promotes the transition of CD4 effectors to persistent memory cells.

    JiChu Li;Gail Huston;Susan L. Swain

  • Costimulatory requirements of naive CD4+ T cells. ICAM-1 or B7-1 can costimulate naive CD4 T cell activation but both are required for optimum response.

    C Dubey;M Croft;S L Swain

Frequent Co-Authors

Richard W. Dutton
Richard W. Dutton University of Massachusetts Chan Medical School
Laura Haynes
Laura Haynes University of Connecticut
Michael Croft
Michael Croft La Jolla Institute For Allergy & Immunology
David L. Woodland
David L. Woodland Trudeau Institute
Andrea M. Cooper
Andrea M. Cooper University of Leicester
Johan Alme
Johan Alme University of Bergen
Gunther Dennert
Gunther Dennert University of Southern California

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