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Immunology

D-Index
54
Citations
12766
World Ranking
3869
National Ranking
1772

Overview

Laura Haynes is affiliated with the University of Connecticut in the United States. Their scholarly work primarily focuses on the fields of Medicine and Immunology and Microbiology, with a significant number of publications in these domains.

The areas of study that feature prominently in their research include Immunology, Epidemiology, Physiology, Neurology, and Genetics. Their work addresses several specific topics such as Immune cells in cancer, Influenza Virus Research Studies, Immune Cell Function and Interaction, Telomeres, Telomerase, and Senescence, Neutrophil, Myeloperoxidase and Oxidative Mechanisms, Neuroinflammation and Neurodegeneration Mechanisms, and Immune Response and Inflammation.

Their recent notable publications consist of:

  • The immune response to influenza in older humans: beyond immune senescence, 2020, Immunity & Ageing
  • An inducible p21-Cre mouse model to monitor and manipulate p21-highly-expressing senescent cells in vivo, 2021, Nature Aging
  • Aging of the Immune System: Research Challenges to Enhance the Health Span of Older Adults, 2020, Frontiers in Aging
  • Moving geroscience from the bench to clinical care and health policy, 2021, Journal of the American Geriatrics Society
  • Age-related factors that affect B cell responses to vaccination in mice and humans, 2020, Immunological Reviews

Frequent co-authors in their body of work include:

  • Blake L. Torrance
  • George A. Kuchel
  • Jenna M. Bartley
  • Erica C. Lorenzo
  • Chris P. Verschoor

Their publications are often featured in several venues, notably:

  • Frontiers in Aging
  • Innovation in Aging
  • Immunity & Ageing
  • Frontiers in Immunology
  • bioRxiv (Cold Spring Harbor Laboratory)

Best Publications

  • IL-23 and IL-17 in the establishment of protective pulmonary CD4 + T cell responses after vaccination and during Mycobacterium tuberculosis challenge

    Shabaana A Khader;Guy K Bell;John E Pearl;Jeffrey J Fountain

  • Reciprocal regulation of polarized cytokine production by effector B and T cells.

    David P. Harris;Laura Haynes;Peter C. Sayles;Debra K. Duso

  • The induction of antibody production by IL-6 is indirectly mediated by IL-21 produced by CD4+ T cells.

    Oliver Dienz;Sheri M. Eaton;Jeffrey P. Bond;Wendy Neveu

  • Interferon γ Eliminates Responding Cd4 T Cells during Mycobacterial Infection by Inducing Apoptosis of Activated Cd4 T Cells

    Dyana K. Dalton;Laura Haynes;Cong Qiu Chu;Susan L. Swain

  • Age-related defects in CD4 T cell cognate helper function lead to reductions in humoral responses.

    Sheri M. Eaton;Eve M. Burns;Kimberly Kusser;Troy D. Randall

  • IL-7: maintaining T-cell memory and achieving homeostasis

    Linda M. Bradley;Laura Haynes;Susan L. Swain

  • Essential role of IL-6 in protection against H1N1 influenza virus by promoting neutrophil survival in the lung.

    Oliver Dienz;Jonathan G. Rud;Sheri M. Eaton;Paula A. Lanthier

  • From Naive to Memory T Cells

    Susan L. Swain;Michael Croft;Caroline Dubey;Laura Haynes

  • CD4 T cell memory derived from young naive cells functions well into old age, but memory generated from aged naive cells functions poorly.

    Laura Haynes;Sheri M. Eaton;Eve M. Burns;Troy D. Randall

  • Antigen-independent changes in naive CD4 T cells with aging.

    P J Linton;L Haynes;N R Klinman;S L Swain

  • Effects of aging on T cell function

    Laura Haynes;Alexander C Maue

  • Interleukin 2, but not other common gamma chain-binding cytokines, can reverse the defect in generation of CD4 effector T cells from naive T cells of aged mice.

    Laura Haynes;Phyllis-Jean Linton;Sheri M. Eaton;Susan L. Tonkonogy

  • Unexpected prolonged presentation of influenza antigens promotes CD4 T cell memory generation.

    Dawn M. Jelley-Gibbs;Deborah M. Brown;John P. Dibble;Laura Haynes

  • Contributions of Antinucleoprotein IgG to Heterosubtypic Immunity against Influenza Virus

    Mark W. LaMere;Ho-Tak Lam;Amy Moquin;Laura Haynes

  • T-cell immunosenescence: lessons learned from mouse models of aging

    Alexander C. Maue;Eric J. Yager;Susan L. Swain;David L. Woodland

  • Inflammatory cytokines overcome age-related defects in CD4 T cell responses in vivo

    Laura Haynes;Sheri M. Eaton;Eve M. Burns;Mercedes Rincon

  • Why Aging T Cells Fail: Implications for Vaccination

    Laura Haynes;Susan L. Swain

  • Age-associated increase in lifespan of naïve CD4 T cells contributes to T-cell homeostasis but facilitates development of functional defects

    Hirotake Tsukamoto;Karen Clise-Dwyer;Gail E. Huston;Debra K. Duso

  • Interdisciplinary Critique of Sipuleucel-T as Immunotherapy in Castration-Resistant Prostate Cancer

    Marie L. Huber;Laura Haynes;Chris Parker;Peter Iversen

  • From naive to effector--alterations with aging.

    Phyllis-Jean Linton;Laura Haynes;Lisa Tsui;Xiaohong Zhang

Frequent Co-Authors

Susan L. Swain
Susan L. Swain University of Massachusetts Chan Medical School
Janet E. McElhaney
Janet E. McElhaney Health Sciences North
Troy D. Randall
Troy D. Randall University of Alabama at Birmingham
Mercedes Rincon
Mercedes Rincon University of Vermont
Graham Pawelec
Graham Pawelec University of Tübingen
David L. Woodland
David L. Woodland Trudeau Institute
Nicholas Cohen
Nicholas Cohen University of Rochester
Shelly A. McNeil
Shelly A. McNeil Dalhousie University
Steven G. Reed
Steven G. Reed Infectious Disease Research Institute
Frances E. Lund
Frances E. Lund University of Alabama at Birmingham

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