Hsin-Chen Lee

Overview

Best Publications

• Mitochondrial biogenesis and mitochondrial DNA maintenance of mammalian cells under oxidative stress.

  Hsin Chen Lee;Yau Huei Wei

  835
  Citations

• Oxidative Stress, Mitochondrial DNA Mutation, and Impairment of Antioxidant Enzymes in Aging

  Yau Huei Wei;Hsin Chen Lee

  810
  Citations

• Increase of mitochondria and mitochondrial DNA in response to oxidative stress in human cells.

  Hsin Chen Lee;Pen Hui Yin;Ching You Lu;Chin Wen Chi

  665
  Citations

• Mitochondrial DNA Mutations and Mitochondrial DNA Depletion in Breast Cancer

  Ling Ming Tseng;Pen Hui Yin;Pen Hui Yin;Chin Wen Chi;Chin Wen Chi;Chih Yi Hsu

  522
  Citations

• Mitochondrial role in life and death of the cell.

  Hsin Chen Lee;Yau Huei Wei

  421
  Citations

• Increase in Mitochondrial Mass in Human Fibroblasts under Oxidative Stress and during Replicative Cell Senescence

  Hsin Chen Lee;Pen Hui Yin;Chin Wen Chi;Yau Huei Wei

  377
  Citations

• Oxidative Damage and Mutation to Mitochondrial DNA and Age-dependent Decline of Mitochondrial Respiratory Functiona

  Yau Huei Wei;Ching You Lu;Hsin Chen Lee;Cheng Yoong Pang

  374
  Citations

• Somatic mutations in the D-loop and decrease in the copy number of mitochondrial DNA in human hepatocellular carcinoma

  Hsin Chen Lee;Shu Hui Li;Jin Ching Lin;Cheng Chung Wu

  362
  Citations

• Mitochondrial genome instability and mtDNA depletion in human cancers.

  Hsin Chen Lee;Pen Hui Yin;Jin Ching Lin;Cheng Chung Wu

  357
  Citations

• Oxidative stress, mitochondrial DNA mutation, and apoptosis in aging.

  Hsin Chen Lee;Yau Huei Wei

  353
  Citations

• Differential accumulations of 4,977 bp deletion in mitochondrial DNA of various tissues in human ageing

  Hsin Chen Lee;Cheng Yoong Pang;Hueih Shing Hsu;Yau Huei Wei

  330
  Citations

• Mitochondria and aging.

  Hsin Chen Lee;Yau Huei Wei;Yau Huei Wei

  294
  Citations

• Role of mitochondrial dysfunction in cancer progression

  Chia Chi Hsu;Ling Ming Tseng;Hsin Chen Lee

  293
  Citations

• CHAC1 degradation of glutathione enhances cystine-starvation-induced necroptosis and ferroptosis in human triple negative breast cancer cells via the GCN2-eIF2α-ATF4 pathway.

  Meng-Shian Chen;Sheng-Fan Wang;Sheng-Fan Wang;Chih-Yi Hsu;Pen-Hui Yin

  266
  Citations

• Alteration of the copy number and deletion of mitochondrial DNA in human hepatocellular carcinoma

  P H Yin;H C Lee;H C Lee;G Y Chau;G Y Chau;Y T Wu

  247
  Citations

• Oxidative damage elicited by imbalance of free radical scavenging enzymes is associated with large-scale mtDNA deletions in aging human skin.

  Ching You Lu;Hsin Chen Lee;Huei Jyh Fahn;Yau Huei Wei

  245
  Citations

• Aging- and smoking-associated alteration in the relative content of mitochondrial DNA in human lung

  Hsin Chen Lee;Ching You Lu;Huei Jyh Fahn;Yau Huei Wei

  209
  Citations

• Oxidative stress in human aging and mitochondrial disease-consequences of defective mitochondrial respiration and impaired antioxidant enzyme system.

  Yau Huei Wei;Ching You Lu;Chia Yu Wei;Yi Shing Ma

  205
  Citations

• Enhanced oxidative stress and aberrant mitochondrial biogenesis in human neuroblastoma SH-SY5Y cells during methamphetamine induced apoptosis.

  Chi Wei Wu;Yueh Hsin Ping;Yueh Hsin Ping;Jiin Cherng Yen;Jiin Cherng Yen;Chia Yu Chang

  183
  Citations

• Mitochondrial DNA mutations and mitochondrial DNA depletion in breast cancer. Genes Chromosomes Cancer

  Ling-Ming Tseng;Pen-Hui Yin;Chin-Wen Chi;Chih-Yi Hsu

  14
  Citations