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Medicine

D-Index
107
Citations
42702
World Ranking
6248
National Ranking
608

Overview

Nicholas W. Morrell is affiliated with the University of Cambridge in the United Kingdom. Their research primarily focuses on the intersection of pulmonary and respiratory medicine, molecular biology, and cardiology and cardiovascular medicine, with significant contributions in genetics and cancer research subfields.

The scientist's work extensively covers subjects in pulmonary hypertension research and treatments. Other notable topics include medical imaging and pathology studies, interstitial lung diseases including idiopathic pulmonary fibrosis, cancer-related molecular mechanisms, TGF-β signaling in diseases, renin-angiotensin system studies, and congenital heart defects research.

Frequent co-authors collaborating with Nicholas W. Morrell include Stefan Gräf, Martin R. Wilkins, Paul D. Upton, Emilia M. Swietlik, and Christopher J. Rhodes.

Key publication venues for Morrell's research are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • European Respiratory Journal
  • Pulmonary Circulation
  • Circulation
  • American Journal of Respiratory and Critical Care Medicine

Recent papers published by Nicholas W. Morrell include:

  • Single-cell RNA sequencing profiling of mouse endothelial cells in response to pulmonary arterial hypertension, 2021, Cardiovascular Research
  • Potential long-term effects of SARS-CoV-2 infection on the pulmonary vasculature: a global perspective, 2021, Nature Reviews Cardiology
  • Mendelian randomisation and experimental medicine approaches to interleukin-6 as a drug target in pulmonary arterial hypertension, 2021, European Respiratory Journal
  • BMPR2 Mutation and Metabolic Reprogramming in Pulmonary Arterial Hypertension, 2023, Circulation Research
  • Circulating BMP9 Protects the Pulmonary Endothelium during Inflammation-induced Lung Injury in Mice, 2020, American Journal of Respiratory and Critical Care Medicine

Their body of work is situated primarily within medicine and biochemistry, genetics, and molecular biology, reflecting a multidisciplinary approach to understanding pulmonary diseases and cardiovascular conditions from genetic and molecular perspectives.

Best Publications

  • Cellular and molecular pathobiology of pulmonary arterial hypertension.

    Marc Humbert;Nicholas W. Morrell;Stephen L. Archer;Kurt R. Stenmark

  • Genomic atlas of the human plasma proteome.

    Benjamin Sun;Joseph C Maranville;James E Peters;James E Peters;David Stacey

  • Cellular and molecular basis of pulmonary arterial hypertension.

    Nicholas W. Morrell;Serge Adnot;Stephen L. Archer;Jocelyn Dupuis

  • Clinical and molecular genetic features of pulmonary hypertension in patients with hereditary hemorrhagic telangiectasia

    Richard Trembath;J R Thomson;Rajiv Machado;N Morgan

  • Inflammation, growth factors, and pulmonary vascular remodeling.

    Paul M. Hassoun;Luc Mouthon;Joan A. Barberà;Saadia Eddahibi

  • Elevated Levels of Inflammatory Cytokines Predict Survival in Idiopathic and Familial Pulmonary Arterial Hypertension

    Elaine Soon;Alan M. Holmes;Carmen M. Treacy;Natalie J. Doughty

  • Primary pulmonary hypertension is associated with reduced pulmonary vascular expression of type II bone morphogenetic protein receptor.

    Carl Atkinson;Susan Stewart;Paul D. Upton;Rajiv D. Machado

  • Altered growth responses of pulmonary artery smooth muscle cells from patients with primary pulmonary hypertension to transforming growth factor-beta(1) and bone morphogenetic proteins.

    Nicholas W. Morrell;Xudong Yang;Paul D. Upton;Karen B. Jourdan

  • Relevant issues in the pathology and pathobiology of pulmonary hypertension

    Rubin M Tuder;Stephen L Archer;Peter Dorfmüller;Serpil C Erzurum

  • Sildenafil Inhibits Hypoxia-Induced Pulmonary Hypertension

    L. Zhao;N.A. Mason;N.W. Morrell;B. Kojonazarov

  • Imatinib Mesylate as Add-On Therapy for Pulmonary Arterial Hypertension: Results of the Randomized IMPRES Study

    Marius M. Hoeper;Robyn J. Barst;Robert C. Bourge;Jeremy Feldman

  • Whole-genome sequencing of patients with rare diseases in a national health system.

    E Turro;W J Astle;W J Astle;K Megy;S Gräf

  • Mutations of the TGF-beta type II receptor BMPR2 in pulmonary arterial hypertension.

    Rajiv D. Machado;Micheala A. Aldred;Victoria James;Rachel E. Harrison

  • Molecular and cellular basis of pulmonary vascular remodeling in pulmonary hypertension

    T.K. Jeffery;N.W. Morrell

  • Selective enhancement of endothelial BMPR-II with BMP9 reverses pulmonary arterial hypertension.

    Lu Long;Mark Leonard Ormiston;XuDong Yang;Mark Southwood

  • ETA and ETB Receptors Modulate the Proliferation of Human Pulmonary Artery Smooth Muscle Cells

    Neil Davie;Stephen J. Haleen;Paul D. Upton;Julia M. Polak

  • Imatinib in Pulmonary Arterial Hypertension Patients with Inadequate Response to Established Therapy

    Hossein A. Ghofrani;Nicholas W. Morrell;Marius M. Hoeper;Horst Olschewski

  • Dysfunctional Smad Signaling Contributes to Abnormal Smooth Muscle Cell Proliferation in Familial Pulmonary Arterial Hypertension

    Xudong Yang;Lu Long;Mark Southwood;Nung Rudarakanchana

  • Molecular and functional analysis identifies ALK-1 as the predominant cause of pulmonary hypertension related to hereditary haemorrhagic telangiectasia

    R E Harrison;J A Flanagan;M Sankelo;S A Abdalla

  • Genetics and genomics of pulmonary arterial hypertension.

    Nicholas W. Morrell;Micheala A. Aldred;Wendy K. Chung;C. Gregory Elliott

Frequent Co-Authors

Richard C. Trembath
Richard C. Trembath King's College London
Marc Humbert
Marc Humbert University of Paris-Saclay
Kurt R. Stenmark
Kurt R. Stenmark University of Colorado Anschutz Medical Campus
Paul A. Corris
Paul A. Corris Newcastle University
Sheila E. Francis
Sheila E. Francis University of Sheffield
Florent Soubrier
Florent Soubrier Université Paris Cité
David Montani
David Montani University of Paris-Saclay
Hossein Ardeschir Ghofrani
Hossein Ardeschir Ghofrani University of Giessen
Edwin R. Chilvers
Edwin R. Chilvers Imperial College London
Ralph T. Schermuly
Ralph T. Schermuly University of Giessen

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