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Florent Soubrier

Florent Soubrier

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Genetics
France
2024

D-Index & Metrics

Genetics

D-Index
89
Citations
38016
World Ranking
1106
National Ranking
40

Research.com Recognitions

  • 2024 - Research.com Genetics in France Leader Award

Overview

Florent Soubrier is affiliated with Université Paris Cité in France. Their research primarily focuses on pulmonary and respiratory medicine, with extensive work in medicine overall.

The main fields of study for Soubrier include:

  • Medicine

Within medicine, their subfields of study encompass:

  • Pulmonary and Respiratory Medicine
  • Molecular Biology
  • Genetics
  • Cardiology and Cardiovascular Medicine
  • Surgery

Their research topics cover several areas related to pulmonary health and vascular conditions, including:

  • Pulmonary Hypertension Research and Treatments
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • Vascular Anomalies and Treatments
  • Medical Imaging and Pathology Studies
  • Renin-Angiotensin System Studies
  • Vascular Malformations Diagnosis and Treatment
  • Congenital Heart Disease Studies

Frequent venues where Soubrier's work has been published include:

  • European Respiratory Journal
  • Circulation
  • Nature Communications
  • American Journal of Respiratory Cell and Molecular Biology
  • American Journal of Respiratory and Critical Care Medicine

Some of the recent papers authored or co-authored by Soubrier are:

  • Screening for pulmonary arterial hypertension in adults carrying a BMPR2 mutation, 2020, European Respiratory Journal
  • Single-Cell Study of Two Rat Models of Pulmonary Arterial Hypertension Reveals Connections to Human Pathobiology and Drug Repositioning, 2020, American Journal of Respiratory and Critical Care Medicine
  • Mendelian randomisation and experimental medicine approaches to interleukin-6 as a drug target in pulmonary arterial hypertension, 2021, European Respiratory Journal
  • Rare variant analysis of 4241 pulmonary arterial hypertension cases from an international consortium implicates FBLN2, PDGFD, and rare de novo variants in PAH, 2021, Genome Medicine
  • Familial pulmonary arterial hypertension by KDR heterozygous loss of function, 2020, European Respiratory Journal

Frequent co-authors in their research collaborations include:

  • David Montani
  • Mélanie Eyries
  • Marc Humbert
  • Barbara Girerd
  • Stefan Gräf

Best Publications

  • An insertion/deletion polymorphism in the angiotensin I-converting enzyme gene accounting for half the variance of serum enzyme levels.

    B Rigat;C Hubert;F Alhenc-Gelas;F Cambien

  • Deletion polymorphism in the gene for angiotensin-converting enzyme is a potent risk factor for myocardial infarction.

    F Cambien;O Poirier;L Lecerf;A Evans

  • Molecular basis of human hypertension: Role of angiotensinogen

    Xavier Jeunemaitre;Florent Soubrier;Yuri V. Kotelevtsev;Richard P. Lifton;Richard P. Lifton

  • PCR detection of the insertion/deletion polymorphism of the human angiotensin converting enzyme gene (DCP1) (dipeptidyl carboxypeptidase 1)

    Brigitte Rigat;Christine Hubert;Pierre Corvol;Florent Soubrier

  • Evidence, from combined segregation and linkage analysis, that a variant of the angiotensin I-converting enzyme (ACE) gene controls plasma ACE levels.

    L Tiret;B Rigat;S Visvikis;C Breda

  • Angiotensin II type 1 receptor gene polymorphisms in human essential hypertension.

    Alain Bonnardeaux;Eleanor Davies;Xavier Jeunemaitre;Isabelle Fery

  • Two putative active centers in human angiotensin I-converting enzyme revealed by molecular cloning.

    Florent Soubrier;Francois Alhenc-Gelas;Christine Hubert;Jacqueline Allegrini

  • Genetics and genomics of pulmonary arterial hypertension

    Florent Soubrier;Wendy K. Chung;Rajiv Machado;Ekkehard Grünig

  • Chromosomal mapping of two genetic loci associated with blood-pressure regulation in hereditary hypertensive rats.

    P. Hilbert;K. Lindpaintner;K. Lindpaintner;J. S. Beckmann;T. Serikawa

  • Structure of the angiotensin I-converting enzyme gene. Two alternate promoters correspond to evolutionary steps of a duplicated gene.

    Christine Hubert;Anne-Marie Houot;Pierre Corvol;Florent Soubrier

  • Synergistic effects of angiotensin-converting enzyme and angiotensin-II type 1 receptor gene polymorphisms on risk of myocardial infarction.

    L Tiret;P Ducimetière;A Bonnardeaux;F Soubrier

  • The deletion/insertion polymorphism of the angiotensin converting enzyme gene and cardiovascular-renal risk

    Jan A. Staessen;Ji G. Wang;Giuliana Ginocchio;Victor Petrov

  • Mutations of the TGF-beta type II receptor BMPR2 in pulmonary arterial hypertension.

    Rajiv D. Machado;Micheala A. Aldred;Victoria James;Rachel E. Harrison

  • A novel channelopathy in pulmonary arterial hypertension.

    Lijiang Ma;Danilo Roman-Campos;Eric D. Austin;Mélanie Eyries

  • EIF2AK4 mutations cause pulmonary veno-occlusive disease, a recessive form of pulmonary hypertension

    Mélanie Eyries;David Montani;Barbara Girerd;Claire Perret

  • Pulmonary veno-occlusive disease

    David Montani;Edmund M Lau;Peter Dorfmüller;Barbara Girerd

  • Genetics and genomics of pulmonary arterial hypertension.

    Nicholas W. Morrell;Micheala A. Aldred;Wendy K. Chung;C. Gregory Elliott

  • Influence of Angiotensin-Converting Enzyme and Angiotensin II Type 1 Receptor Gene Polymorphisms on Aortic Stiffness in Normotensive and Hypertensive Patients

    Athanase Benetos;Sylvie Gautier;Sylvain Ricard;Jirar Topouchian

  • Peptidyl dipeptidase A : Angiotensin I-converting enzyme

    Pierre Corvol;Tracy A. Williams;Florent Soubrier

  • PCR DETECTION OF THE INSERTION/ DELETION POLYMORPHISM OF THE HUMAN ANGIOTENSIN CONVERTING ENZYME GENE

    B Rigat;C Hubert;P Corvol;F Soubrier

Frequent Co-Authors

Pierre Corvol
Pierre Corvol Collège de France
Marc Humbert
Marc Humbert University of Paris-Saclay
David Montani
David Montani University of Paris-Saclay
Gérald Simonneau
Gérald Simonneau University of Paris-Saclay
Olivier Sitbon
Olivier Sitbon University of Paris-Saclay
Richard C. Trembath
Richard C. Trembath King's College London
Xavier Jeunemaitre
Xavier Jeunemaitre Université Paris Cité
Nicholas W. Morrell
Nicholas W. Morrell University of Cambridge
Xavier Jaïs
Xavier Jaïs University of Paris-Saclay
David-Alexandre Trégouët
David-Alexandre Trégouët University of Bordeaux

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